(Q28539153)

English

Platelet aggregation unchanged by lipoprotein-associated phospholipase A₂ inhibition: results from an in vitro study and two randomized phase I trials

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scholarly article

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Platelet aggregation unchanged by lipoprotein-associated phospholipase A₂ inhibition: results from an in vitro study and two randomized phase I trials (English)

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phase I clinical trial

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platelet aggregation

1 reference

based on heuristic

inferred from title

author name string

Bonnie C Shaddinger

1

author given names

Bonnie C

author last names

Shaddinger

1 reference

PubMed publication ID

5 December 2023

Yanmei Xu

2

author given names

Yanmei

author last names

Xu

1 reference

PubMed publication ID

5 December 2023

James H Roger

3

author given names

James H

author last names

Roger

1 reference

PubMed publication ID

5 December 2023

Colin H Macphee

4

author given names

Colin H

author last names

Macphee

1 reference

PubMed publication ID

5 December 2023

Malcolm Handel

5

author given names

Malcolm

author last names

Handel

1 reference

PubMed publication ID

5 December 2023

Charlotte A Baidoo

6

author given names

Charlotte A

author last names

Baidoo

1 reference

PubMed publication ID

5 December 2023

Mindy Magee

7

author given names

Mindy

author last names

Magee

1 reference

PubMed publication ID

5 December 2023

John J Lepore

8

author given names

John J

author last names

Lepore

1 reference

PubMed publication ID

5 December 2023

Dennis L Sprecher

9

author given names

Dennis L

author last names

Sprecher

1 reference

PubMed publication ID

5 December 2023

language of work or name

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publication date

2014

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9

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1

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e83094

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copyright license

Creative Commons Attribution 4.0 International

27 January 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

The Ile198Thr and Ala379Val variants of plasmatic PAF-acetylhydrolase impair catalytical activities and are associated with atopy and asthma

1 reference

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19 March 2017

Platelet-activating factor acetylhydrolase deficiency. A missense mutation near the active site of an anti-inflammatory phospholipase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3903475

19 March 2017

A specific acetylhydrolase for 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine (a hypotensive and platelet-activating lipid)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3903475

19 March 2017

CONSORT 2010 statement: updated guidelines for reporting parallel group randomized trials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3903475

7 April 2017

Circulating platelet-activating factor is primarily cleared by transport, not intravascular hydrolysis by lipoprotein-associated phospholipase A2/ PAF acetylhydrolase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3903475

29 September 2017

Lipoprotein-associated phospholipase A(2) and atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3903475

29 September 2017

The effect of darapladib on plasma lipoprotein-associated phospholipase A2 activity and cardiovascular biomarkers in patients with stable coronary heart disease or coronary heart disease risk equivalent: the results of a multicenter, randomized, dou

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3903475

29 September 2017

Platelet-activating factor, PAF acetylhydrolase, and severe anaphylaxis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3903475

29 September 2017

Deficiency of platelet-activating factor acetylhydrolase is a severity factor for asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3903475

29 September 2017

Platelet-activating factor and its analogs: metabolic pathways and related intracellular processes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3903475

29 September 2017

Human plasma platelet-activating factor acetylhydrolase. Association with lipoprotein particles and role in the degradation of platelet-activating factor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3903475

29 September 2017

Characterization of serum platelet-activating factor (PAF) acetylhydrolase. Correlation between deficiency of serum PAF acetylhydrolase and respiratory symptoms in asthmatic children

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3903475

29 September 2017

Specific receptors of platelet-activating factor, receptor heterogeneity, and signal transduction mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3903475

29 September 2017

Letter: Aggregation of human platelets by platelet-activating factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3903475

29 September 2017

Increased plasma level of platelet-activating factor (PAF) and decreased serum PAF acetylhydrolase (PAFAH) activity in adults with bronchial asthma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3903475

3 June 2018

Platelet-activating factor is a general membrane perturbant

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3903475

3 June 2018

Concurrent morning increase in platelet aggregability and the risk of myocardial infarction and sudden cardiac death.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3903475

20 June 2018

Study design and rationale for the clinical outcomes of the STABILITY Trial (STabilization of Atherosclerotic plaque By Initiation of darapLadIb TherapY) comparing darapladib versus placebo in patients with coronary heart disease

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0083094

21 January 2018

Secondary prevention and risk factor target achievement in a global, high-risk population with established coronary heart disease: baseline results from the STABILITY study

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0083094

21 January 2018

PAF responsiveness in Japanese subjects with plasma PAF acetylhydrolase deficiency

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0083094

21 January 2018

Lipoprotein-associated phospholipase A2 activity is associated with risk of coronary heart disease and ischemic stroke: the Rotterdam Study

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0083094

21 January 2018

Study design and rationale for the Stabilization of pLaques usIng Darapladib—Thrombolysis in Myocardial Infarction (SOLID-TIMI 52) trial in patients after an acute coronary syndrome

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0083094

21 January 2018

Evidence for an association between plasma platelet-activating factor acetylhydrolase deficiency and increased risk of childhood atopic asthma

1 reference

https://pubmed.ncbi.nlm.nih.gov/24475026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preliminary studies of an acid-labile factor (ALF) in human sera that inactivates platelet-activating factor (PAF)

1 reference

https://pubmed.ncbi.nlm.nih.gov/24475026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of platelet-activating factor (PAF) on human platelets

1 reference

https://pubmed.ncbi.nlm.nih.gov/24475026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human plasma platelet-activating factor acetylhydrolase. Purification and properties

1 reference

https://pubmed.ncbi.nlm.nih.gov/24475026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deficiency of plasma platelet-activating factor acetylhydrolase: roles of blood cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/24475026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of platelet-activating factor acetylhydrolase in human bronchoalveolar lavage

1 reference

https://pubmed.ncbi.nlm.nih.gov/24475026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma platelet-activating factor acetylhydrolase deficiency in Japanese patients with asthma

1 reference

https://pubmed.ncbi.nlm.nih.gov/24475026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of recombinant human platelet-activating factor-acetylhydrolase on allergen-induced asthmatic responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/24475026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0083094

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2014PLoSO...983094S

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PMC publication ID

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PubMed publication ID

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ResearchGate publication ID

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