(Q28557128)

Calpain large subunit, domain III superfamily

1 reference

EF-hand domain pair

1 reference

Papain-like cysteine peptidase superfamily

1 reference

EF-hand domain, protein family

1 reference

Peptidase C2, calpain, large subunit, domain III, protein family

1 reference

Peptidase C2, calpain, domain III, protein family

1 reference

Calpain subdomain III, protein family

1 reference

Peptidase C2, calpain, catalytic domain, protein family

1 reference

Cysteine peptidase, cysteine active site, protein family

1 reference

EF-Hand 1, calcium-binding site, protein family

1 reference

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16259

1 reference

17 November 2021

1 reference

17 November 2021

1 reference

8 April 2019

calcium-dependent cysteine-type endopeptidase activity

4 references

8 April 2019

Calpain 3 is expressed in astrocytes of rat and Microcebus brain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16259

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16259

8 April 2019

Characterization and regulation of lens-specific calpain Lp82

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16259

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16259

signaling receptor binding

IBA

1 reference

8 April 2019

Novel role of calpain-3 in the triad-associated protein complex regulating calcium release in skeletal muscle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16259

1 reference

8 April 2019

Detection and localization of calpain 3-like protease in a neuronal cell line: possible regulation of apoptotic cell death through degradation of nuclear IkappaBalpha

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16259

cysteine-type peptidase activity

IPI

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16259

structural constituent of muscle

IEA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16259

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16259

1 reference

8 April 2019

Novel role of calpain-3 in the triad-associated protein complex regulating calcium release in skeletal muscle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16259

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16259

1 reference

8 April 2019

Endogenous calpain-3 activation is primarily governed by small increases in resting cytoplasmic [Ca2+] and is not dependent on stretch

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16259

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16259

ligase regulator activity

IEA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16259

1 reference

8 April 2019

Detection and localization of calpain 3-like protease in a neuronal cell line: possible regulation of apoptotic cell death through degradation of nuclear IkappaBalpha

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16259

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16259

8 April 2019

Detection and localization of calpain 3-like protease in a neuronal cell line: possible regulation of apoptotic cell death through degradation of nuclear IkappaBalpha

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16259

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16259

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16259

1 reference

8 April 2019

Endogenous calpain-3 activation is primarily governed by small increases in resting cytoplasmic [Ca2+] and is not dependent on stretch

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16259

1 reference

8 April 2019

Endogenous calpain-3 activation is primarily governed by small increases in resting cytoplasmic [Ca2+] and is not dependent on stretch

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16259

1 reference

8 April 2019

Endogenous calpain-3 activation is primarily governed by small increases in resting cytoplasmic [Ca2+] and is not dependent on stretch

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16259

protein-containing complex

IDA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16259

5 references

8 April 2019

Calpain 3 is expressed in astrocytes of rat and Microcebus brain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16259

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16259

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16259

8 April 2019

Novel role of calpain-3 in the triad-associated protein complex regulating calcium release in skeletal muscle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16259

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16259

positive regulation of satellite cell activation involved in skeletal muscle regeneration

IBA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16259

response to muscle activity

1 reference

8 April 2019

Endogenous calpain-3 activation is primarily governed by small increases in resting cytoplasmic [Ca2+] and is not dependent on stretch

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16259

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16259

negative regulation of protein sumoylation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16259

regulation of I-kappaB kinase/NF-kappaB signaling

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16259

positive regulation of proteolysis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16259

negative regulation of transcription, DNA-templated

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16259

positive regulation of transcription, DNA-templated

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16259

regulation of catalytic activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16259

positive regulation of NF-kappaB transcription factor activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16259

positive regulation of release of sequestered calcium ion into cytosol

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16259

Characterization and regulation of lens-specific calpain Lp82

response to calcium ion

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16259

muscle structure development

IDA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16259

protein-containing complex assembly

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16259

cellular response to calcium ion

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16259

cellular response to salt stress

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16259

protein localization to membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16259

sodium-dependent self proteolysis

1 reference

8 April 2019

Skeletal muscle-specific calpain is an intracellular Na+-dependent protease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16259

calcium-dependent self proteolysis

IDA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16259

Peptidase C2, calpain, large subunit, domain III

has part(s)

1 reference

Peptidase C2, calpain, domain III

1 reference

Cysteine peptidase, cysteine active site

1 reference

EF-hand domain

1 reference

Calpain subdomain III

1 reference

Peptidase C2, calpain, catalytic domain

1 reference

EF-hand 1, calcium-binding site

1 reference