(Q28557265)

English

Drebrin 1

mammalian protein found in Rattus norvegicus

drebrin
Dbn1
drebrin E
developmentally-regulated brain protein

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

ADF-H/Gelsolin-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q07266

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q07266

Actin-depolymerising factor homology domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

protein binding

determination method

7 references

8 April 2019

Connexin43 Forms Supramolecular Complexes through Non-Overlapping Binding Sites for Drebrin, Tubulin, and ZO-1.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

8 April 2019

Spikar, a novel drebrin-binding protein, regulates the formation and stabilization of dendritic spines

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

8 April 2019

Proteomic analysis of TRPC5- and TRPC6-binding partners reveals interaction with the plasmalemmal Na(+)/K(+)-ATPase

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

8 April 2019

Phosphorylation of the actin binding protein Drebrin at S647 is regulated by neuronal activity and PTEN

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

8 April 2019

Phosphorylation of the actin binding protein Drebrin at S647 is regulated by neuronal activity and PTEN

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

8 April 2019

Spikar, a novel drebrin-binding protein, regulates the formation and stabilization of dendritic spines

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

8 April 2019

F-actin-binding protein drebrin regulates CXCR4 recruitment to the immune synapse

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

profilin binding

determination method

1 reference

8 April 2019

Interactions of drebrin and gephyrin with profilin

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

cytoskeletal protein binding

determination method

1 reference

8 April 2019

Actin-binding protein drebrin E is involved in junction dynamics during spermatogenesis

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

actin filament binding

determination method

1 reference

8 April 2019

Drebrin attenuates the interaction between actin and myosin-V

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

determination method

1 reference

8 April 2019

Change in the shape of dendritic spines caused by overexpression of drebrin in cultured cortical neurons

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

plasma membrane

determination method

1 reference

8 April 2019

Drebrin A is a postsynaptic protein that localizes in vivo to the submembranous surface of dendritic sites forming excitatory synapses

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

cell-cell junction

determination method

1 reference

8 April 2019

Actin-binding protein drebrin E is involved in junction dynamics during spermatogenesis

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

postsynaptic density

determination method

1 reference

8 April 2019

Drebrin A is a postsynaptic protein that localizes in vivo to the submembranous surface of dendritic sites forming excitatory synapses

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

actin cytoskeleton

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

determination method

1 reference

8 April 2019

Drebrin E is involved in the regulation of axonal growth through actin-myosin interactions

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

determination method

1 reference

8 April 2019

Drebrin E is involved in the regulation of axonal growth through actin-myosin interactions

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

asymmetric synapse

determination method

1 reference

8 April 2019

Drebrin A is a postsynaptic protein that localizes in vivo to the submembranous surface of dendritic sites forming excitatory synapses

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

cell projection

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

neuronal cell body

determination method

1 reference

8 April 2019

Expression of drebrin E in migrating neuroblasts in adult rat brain: coincidence between drebrin E disappearance from cell body and cessation of migration

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

dendritic spine

determination method

1 reference

8 April 2019

Drebrin-dependent actin clustering in dendritic filopodia governs synaptic targeting of postsynaptic density-95 and dendritic spine morphogenesis

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

dendritic shaft

determination method

1 reference

8 April 2019

Drebrin-dependent actin clustering in dendritic filopodia governs synaptic targeting of postsynaptic density-95 and dendritic spine morphogenesis

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

axonal growth cone

determination method

1 reference

8 April 2019

Drebrin E is involved in the regulation of axonal growth through actin-myosin interactions

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

determination method

1 reference

8 April 2019

Drebrin A is a postsynaptic protein that localizes in vivo to the submembranous surface of dendritic sites forming excitatory synapses

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

determination method

1 reference

8 April 2019

Change in the shape of dendritic spines caused by overexpression of drebrin in cultured cortical neurons

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

postsynaptic membrane

determination method

perinuclear region of cytoplasm

determination method

1 reference

8 April 2019

Actin-binding protein drebrin E is involved in junction dynamics during spermatogenesis

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

excitatory synapse

determination method

1 reference

8 April 2019

Drebrin A is a postsynaptic protein that localizes in vivo to the submembranous surface of dendritic sites forming excitatory synapses

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

postsynaptic actin cytoskeleton

determination method

1 reference

8 April 2019

Modulatory role of drebrin on the cytoskeleton within dendritic spines in the rat cerebral cortex.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

glutamatergic synapse

determination method

4 references

8 April 2019

Drebrin-dependent actin clustering in dendritic filopodia governs synaptic targeting of postsynaptic density-95 and dendritic spine morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

8 April 2019

Drebrin-dependent actin clustering in dendritic filopodia governs synaptic targeting of postsynaptic density-95 and dendritic spine morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

8 April 2019

Modulatory role of drebrin on the cytoskeleton within dendritic spines in the rat cerebral cortex.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

8 April 2019

Drebrin-dependent actin clustering in dendritic filopodia governs synaptic targeting of postsynaptic density-95 and dendritic spine morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

dendritic filopodium

determination method

1 reference

8 April 2019

Drebrin-dependent actin clustering in dendritic filopodia governs synaptic targeting of postsynaptic density-95 and dendritic spine morphogenesis

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

biological process

multicellular organism development

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

spermatogenesis

determination method

1 reference

8 April 2019

Actin-binding protein drebrin E is involved in junction dynamics during spermatogenesis

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

brain development

determination method

1 reference

8 April 2019

Drebrin A is a postsynaptic protein that localizes in vivo to the submembranous surface of dendritic sites forming excitatory synapses

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

determination method

1 reference

8 April 2019

Differential expression of rat brain synaptic proteins in development and aging

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

positive regulation of cell-substrate adhesion

determination method

1 reference

8 April 2019

Effect of a neuron-specific actin-binding protein, drebrin A, on cell-substratum adhesion

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

positive regulation of neuron projection development

determination method

response to activity

determination method

1 reference

8 April 2019

Guided motor training induces dendritic spine plastic changes in adult rat cerebellar purkinje cells

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

cell differentiation

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

regulation of actin filament polymerization

determination method

1 reference

8 April 2019

Drebrin E is involved in the regulation of axonal growth through actin-myosin interactions

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

positive regulation of synaptic plasticity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

negative regulation of actin filament bundle assembly

determination method

1 reference

8 April 2019

Inhibition by drebrin of the actin-bundling activity of brain fascin, a protein localized in filopodia of growth cones

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

positive regulation of axon extension

determination method

1 reference

8 April 2019

Drebrin E is involved in the regulation of axonal growth through actin-myosin interactions

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

lung alveolus development

determination method

1 reference

8 April 2019

Temporal expression of alpha-smooth muscle actin and drebrin in septal interstitial cells during alveolar maturation

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

cytoplasmic sequestering of protein

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

regulation of filopodium assembly

determination method

1 reference

8 April 2019

Drebrin-dependent actin clustering in dendritic filopodia governs synaptic targeting of postsynaptic density-95 and dendritic spine morphogenesis

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

prepulse inhibition

determination method

1 reference

8 April 2019

Antisense knockdown of drebrin A, a dendritic spine protein, causes stronger preference, impaired pre-pulse inhibition, and an increased sensitivity to psychostimulant

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

cellular response to tumor necrosis factor

determination method

1 reference

8 April 2019

Actin-binding protein drebrin E is involved in junction dynamics during spermatogenesis

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

cellular response to X-ray

determination method

1 reference

8 April 2019

X irradiation changes dendritic spine morphology and density through reduction of cytoskeletal proteins in mature neurons

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

cellular response to transforming growth factor beta stimulus

determination method

1 reference

8 April 2019

Actin-binding protein drebrin E is involved in junction dynamics during spermatogenesis

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

negative regulation of locomotion involved in locomotory behavior

determination method

1 reference

8 April 2019

Antisense knockdown of drebrin A, a dendritic spine protein, causes stronger preference, impaired pre-pulse inhibition, and an increased sensitivity to psychostimulant

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

modulation of inhibitory postsynaptic potential

determination method

1 reference

8 April 2019

Drebrin A regulates dendritic spine plasticity and synaptic function in mature cultured hippocampal neurons

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

postsynaptic actin cytoskeleton organization

determination method

3 references

8 April 2019

Drebrin-dependent actin clustering in dendritic filopodia governs synaptic targeting of postsynaptic density-95 and dendritic spine morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

8 April 2019

Drebrin-dependent actin clustering in dendritic filopodia governs synaptic targeting of postsynaptic density-95 and dendritic spine morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

8 April 2019

Drebrin-dependent actin clustering in dendritic filopodia governs synaptic targeting of postsynaptic density-95 and dendritic spine morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

positive regulation of substrate adhesion-dependent cell spreading

determination method

1 reference

8 April 2019

Effect of a neuron-specific actin-binding protein, drebrin A, on cell-substratum adhesion

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

positive regulation of receptor localization to synapse

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

regulation of postsynaptic density protein 95 clustering

determination method

1 reference

8 April 2019

Drebrin-dependent actin clustering in dendritic filopodia governs synaptic targeting of postsynaptic density-95 and dendritic spine morphogenesis

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

negative regulation of muscle filament sliding

determination method

1 reference

8 April 2019

Drebrin attenuates the interaction between actin and myosin-V

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

positive regulation of excitatory postsynaptic potential

determination method

1 reference

8 April 2019

Drebrin A regulates dendritic spine plasticity and synaptic function in mature cultured hippocampal neurons

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07266

determination method

Actin-depolymerising factor homology domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q07266

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSRNOP00000019393

1 reference

ensembl Release 106

Ensembl protein ID

ENSRNOP00000019393

ENSRNOP00000019569

1 reference

ensembl Release 106

Ensembl protein ID

ENSRNOP00000019569

Sitelinks

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Wiktionary(0 entries)

Multilingual sites(0 entries)

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