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Thyroid stimulating hormone receptor
mammalian protein found in Rattus norvegicus
thyrotropin receptor
TSH-R
Tshr
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P21463
part of
Leucine-rich repeat domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P21463
Thyrotropin receptor
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P21463
membrane protein
1 reference
based on heuristic
inferred from GOA cell component → membrane
GPCR, rhodopsin-like, 7TM, protein family
1 reference
based on heuristic
inferred from protein domain or family
BspA type Leucine rich repeat region, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
brown rat
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P21463
encoded by
Tshr
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P21463
molecular function
G protein-coupled receptor activity
determination method
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P21463
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21463
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21463
determination method
IEA
thyroid-stimulating hormone receptor activity
determination method
IBA
IEA
IMP
ISS
4 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P21463
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21463
determination method
ISS
retrieved
14 February 2019
stated in
Cloning, chromosomal assignment, and regulation of the rat thyrotropin receptor: expression of the gene is regulated by thyrotropin, agents that increase cAMP levels, and thyroid autoantibodies
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21463
determination method
IMP
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21463
determination method
IEA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21463
determination method
IBA
G protein-coupled peptide receptor activity
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21463
determination method
IBA
protein-hormone receptor activity
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21463
determination method
IEA
signaling receptor activity
determination method
ISS
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P21463
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21463
determination method
ISS
protein-containing complex binding
determination method
ISS
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P21463
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21463
determination method
ISS
cell component
plasma membrane
determination method
IEA
ISS
2 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P21463
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21463
determination method
ISS
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P21463
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21463
determination method
IEA
integral component of plasma membrane
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21463
determination method
IBA
membrane
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P21463
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21463
determination method
IEA
integral component of membrane
determination method
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P21463
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21463
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21463
determination method
IEA
basolateral plasma membrane
determination method
IEA
ISS
2 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P21463
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21463
determination method
ISS
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P21463
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21463
determination method
IEA
membrane raft
determination method
IDA
1 reference
retrieved
14 February 2019
stated in
Lipid rafts are triage centers for multimeric and monomeric thyrotropin receptor regulation
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21463
determination method
IDA
biological process
signal transduction
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P21463
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21463
determination method
IEA
cell surface receptor signaling pathway
determination method
ISS
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P21463
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21463
determination method
ISS
G protein-coupled receptor signaling pathway
determination method
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P21463
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21463
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21463
determination method
IEA
adenylate cyclase-activating G protein-coupled receptor signaling pathway
determination method
IBA
ISS
2 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P21463
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21463
determination method
ISS
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21463
determination method
IBA
activation of adenylate cyclase activity
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21463
determination method
IBA
positive regulation of cell population proliferation
determination method
IDA
1 reference
retrieved
14 February 2019
stated in
Characterization of thyrotropin receptor antibody-induced signaling cascades
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21463
determination method
IDA
hormone-mediated signaling pathway
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21463
determination method
IBA
thyroid-stimulating hormone signaling pathway
determination method
ISS
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P21463
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21463
determination method
ISS
positive regulation of adenylate cyclase activity
determination method
ISS
1 reference
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P21463
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P21463&geneProductId=UniProtKB:P21463
determination method
ISS
positive regulation of cold-induced thermogenesis
determination method
ISS
1 reference
retrieved
14 February 2019
stated in
Thyroid-stimulating hormone receptor in brown adipose tissue is involved in the regulation of thermogenesis
GOA
curator
YuBioLab
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21463
determination method
ISS
cellular response to glycoprotein
determination method
ISS
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P21463
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21463
determination method
ISS
cellular response to thyrotropin-releasing hormone
determination method
ISS
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P21463
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21463
determination method
ISS
has part(s)
BspA type Leucine rich repeat region
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P21463
GPCR, rhodopsin-like, 7TM
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P21463
Identifiers
RefSeq protein ID
NP_037020
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
25360
XP_038967730
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
25360
UniProt protein ID
P21463
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P21463
Ensembl protein ID
ENSRNOP00000005671
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSRNOP00000005671
ENSRNOP00000084487
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSRNOP00000084487
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Wikiquote
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Wikiversity
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Multilingual sites
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