(Q28568440)

31 January 2017

title

Characterization of thyrotropin receptor antibody-induced signaling cascades (English)

1 reference

31 January 2017

Syed A. Morshed

1

1 reference

31 January 2017

Rauf Latif

series ordinal

2

1 reference

31 January 2017

Terry F. Davies

series ordinal

3

1 reference

31 January 2017

language of work or name

English

0 references

publication date

1 January 2009

1 reference

31 January 2017

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31 January 2017

volume

150

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31 January 2017

issue

1

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31 January 2017

page(s)

519–529

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Crystal structure of the TSH receptor in complex with a thyroid-stimulating autoantibody

31 January 2017

cites work

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A human monoclonal autoantibody to the thyrotropin receptor with thyroid-stimulating blocking activity

7 April 2017

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Integrating signals from RTKs to ERK/MAPK.

29 September 2017

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Convergence of the SUMO and MAPK pathways on the ETS-domain transcription factor Elk-1.

29 September 2017

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Differential functions of PKC-delta and PKC-zeta in cisplatin response of normal and transformed thyroid cells.

29 September 2017

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Requirement of thyrotropin-dependent complex formation of protein kinase A catalytic subunit with inhibitor of {kappa}B proteins for activation of p65 nuclear factor-{kappa}B by tumor necrosis factor-{alpha}.

29 September 2017

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Dissecting linear and conformational epitopes on the native thyrotropin receptor.

29 September 2017

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Concentration-dependent regulation of thyrotropin receptor function by thyroid-stimulating antibody.

29 September 2017

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A monoclonal thyroid-stimulating antibody

29 September 2017

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Phosphatidylcholine-specific phospholipase C and RhoA are involved in the thyrotropin-induced activation of phospholipase D in FRTL-5 thyroid cells

29 September 2017

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Differential signaling of cyclic AMP: opposing effects of exchange protein directly activated by cyclic AMP and cAMP-dependent protein kinase on protein kinase B activation

29 September 2017

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Regulation of thyroid cell proliferation by TSH and other factors: a critical evaluation of in vitro models

29 September 2017

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Further evidence that 3-phosphoinositide-dependent protein kinase-1 (PDK1) is required for the stability and phosphorylation of protein kinase C (PKC) isoforms.

29 September 2017

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Cellular signaling: pivoting around PDK-1.

29 September 2017

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Thyrotropin-dependent proliferation of in vitro rat thyroid cell systems

29 September 2017

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Protein kinase A-dependent and -independent signaling pathways contribute to cyclic AMP-stimulated proliferation.

29 September 2017

1 reference

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Role and regulation of 90 kDa ribosomal S6 kinase (RSK) in signal transduction.

29 September 2017

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Intracellular signalling: PDK1--a kinase at the hub of things

29 September 2017

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MAP kinase kinase kinase, MAP kinase kinase and MAP kinase

29 September 2017

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Culture of hormone-dependent functional epithelial cells from rat thyroids

29 September 2017

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Thyroid-stimulating monoclonal antibodies

29 September 2017

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Mechanisms and consequences of activation of protein kinase B/Akt

3 June 2018

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An N-linked glycosylation motif from the noncleaving luteinizing hormone receptor substituted for the homologous region (Gly367 to Glu369) of the thyrotropin receptor prevents cleavage at its second, downstream site

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630889

Stimulation of cell proliferation and inhibition of differentiation expression by tumor-promoting phorbol esters in dog thyroid cells in primary culture.

3 June 2018

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Phorbol esters stimulate growth and inhibit differentiation in cultured thyroid cells

3 June 2018

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Graves' IgG recognizes linear epitopes in the human thyrotropin receptor

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630889

Suppression of thyrotropin receptor constitutive activity by a monoclonal antibody with inverse agonist activity.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630889

Effects of TSH receptor mutations on binding and biological activity of monoclonal antibodies and TSH.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630889

Monoclonal pathogenic antibodies to the thyroid-stimulating hormone receptor in Graves' disease with potent thyroid-stimulating activity but differential blocking activity activate multiple signaling pathways.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630889

Characteristics of a monoclonal antibody to the thyrotropin receptor that acts as a powerful thyroid-stimulating autoantibody antagonist.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630889

Characteristics of a human monoclonal autoantibody to the thyrotropin receptor: sequence structure and function

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630889

Antibodies to TSH-receptor in thyroid autoimmune disease interact with monoclonal antibodies whose epitopes are broadly distributed on the receptor

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630889

The effect of thyrotropin-receptor blocking antibodies on stimulating autoantibodies from patients with Graves' disease

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630889

Thyrotropin-mediated repression of class II trans-activator expression in thyroid cells: involvement of STAT3 and suppressor of cytokine signaling.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630889

The cysteine-rich amino terminus of the thyrotropin receptor is the immunodominant linear antibody epitope in mice immunized using naked deoxyribonucleic acid or adenovirus vectors

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630889

Evidence for a simplified view of autoantibody interactions with the thyrotropin receptor.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630889

Role of cAMP, PKA and Rap1A in thyroid follicular cell survival

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630889

Antibodies against neural, nuclear, cytoskeletal, and streptococcal epitopes in children and adults with Tourette's syndrome, Sydenham's chorea, and autoimmune disorders.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630889

Thyrotropin activates mitogen-activated protein kinase pathway in FRTL-5 by a cAMP-dependent protein kinase A-independent mechanism

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630889

The thyrotropin (TSH) receptor: interaction with TSH and autoantibodies

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630889

27 November 2018

New exchange, new target

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630889

Patient with monoclonal gammopathy, thyrotoxicosis, pretibial myxedema and thyroid-associated ophthalmopathy; demonstration of direct binding of autoantibodies to the thyrotropin receptor.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630889

Activation of the small G protein Rap1 in dog thyroid cells by both cAMP-dependent and -independent pathways

27 November 2018

1 reference

12 December 2020

Detection of functionally different types of pathological autoantibodies against thyrotropin receptor in Graves' patients sera by luminescent immunoprecipitation analysis

1 reference

12 December 2020

Cyclic adenosine 3',5'-monophosphate (cAMP)-dependent protein kinases, but not exchange proteins directly activated by cAMP (Epac), mediate thyrotropin/cAMP-dependent regulation of thyroid cells

1 reference

12 December 2020

Regulation of the phosphatidylinositol 3-kinase, Akt/protein kinase B, FRAP/mammalian target of rapamycin, and ribosomal S6 kinase 1 signaling pathways by thyroid-stimulating hormone (TSH) and stimulating type TSH receptor antibodies in the thyroid

1 reference

12 December 2020

The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells

1 reference

12 December 2020

Identifiers

DOI

10.1210/EN.2008-0878

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1 reference

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