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The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells
scientific article published on 01 April 2000
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1 reference
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Europe PubMed Central
PubMed ID
10801415
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10801415%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
title
The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells
(English)
1 reference
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Europe PubMed Central
PubMed ID
10801415
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10801415%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
author
Simon J. Arthur
series ordinal
2
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Europe PubMed Central
PubMed ID
10801415
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10801415%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
Valeria Poli
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5
1 reference
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Europe PubMed Central
PubMed ID
10801415
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10801415%20AND%20SRC:MED&resulttype=core&format=json
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6 November 2019
Dario Alessi
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7
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Europe PubMed Central
PubMed ID
10801415
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10801415%20AND%20SRC:MED&resulttype=core&format=json
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6 November 2019
author name string
M R Williams
series ordinal
1
1 reference
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Europe PubMed Central
PubMed ID
10801415
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10801415%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
A Balendran
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3
1 reference
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Europe PubMed Central
PubMed ID
10801415
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10801415%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
J van der Kaay
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed ID
10801415
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10801415%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
P Cohen
series ordinal
6
1 reference
stated in
Europe PubMed Central
PubMed ID
10801415
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10801415%20AND%20SRC:MED&resulttype=core&format=json
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6 November 2019
language of work or name
English
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publication date
1 April 2000
1 reference
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Europe PubMed Central
PubMed ID
10801415
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10801415%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
number of pages
10
1 reference
based on heuristic
inferred from page(s)
published in
Current Biology
1 reference
stated in
Europe PubMed Central
PubMed ID
10801415
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10801415%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
volume
10
1 reference
stated in
Europe PubMed Central
PubMed ID
10801415
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10801415%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
page(s)
439-448
1 reference
stated in
Europe PubMed Central
PubMed ID
10801415
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10801415%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
issue
8
1 reference
stated in
Europe PubMed Central
PubMed ID
10801415
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10801415%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
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Role and regulation of 90 kDa ribosomal S6 kinase (RSK) in signal transduction.
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Mechanism of activation of protein kinase B by insulin and IGF-1
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7 January 2021
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Multiple pathways control protein kinase C phosphorylation
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reference URL
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7 January 2021
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The principal target of rapamycin-induced p70s6k inactivation is a novel phosphorylation site within a conserved hydrophobic domain.
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7 January 2021
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Identification of regulatory phosphorylation sites in mitogen-activated protein kinase (MAPK)-activated protein kinase-1a/p90rsk that are inducible by MAPK
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Serum and glucocorticoid-inducible kinase (SGK) is a target of the PI 3-kinase-stimulated signaling pathway
1 reference
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7 January 2021
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Activation of serum- and glucocorticoid-regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2
1 reference
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7 January 2021
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Intracellular signalling: PDK1--a kinase at the hub of things
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Kinase phosphorylation: Keeping it all in the family
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7 January 2021
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Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha
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7 January 2021
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3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase
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7 January 2021
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Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B
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7 January 2021
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Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B
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3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro
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Phosphorylation and activation of p70s6k by PDK1
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7 January 2021
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Ribosomal S6 kinase 1 (RSK1) activation requires signals dependent on and independent of the MAP kinase ERK.
1 reference
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Crossref
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7 January 2021
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inferred from DOI database lookup
90-kDa ribosomal S6 kinase is phosphorylated and activated by 3-phosphoinositide-dependent protein kinase-1.
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900441-3
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7 January 2021
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Regulation of conventional protein kinase C isozymes by phosphoinositide-dependent kinase 1 (PDK-1)
1 reference
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7 January 2021
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Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1
1 reference
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7 January 2021
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Regulation of protein kinase C zeta by PI 3-kinase and PDK-1
1 reference
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Primary structure, tissue distribution, and expression of mouse phosphoinositide-dependent protein kinase-1, a protein kinase that phosphorylates and activates protein kinase Czeta
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900441-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation and activation of cAMP-dependent protein kinase by phosphoinositide-dependent protein kinase
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900441-3
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7 January 2021
based on heuristic
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Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900441-3
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7 January 2021
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The regulation of AMP-activated protein kinase by phosphorylation
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
PDK1 acquires PDK2 activity in the presence of a synthetic peptide derived from the carboxyl terminus of PRK2.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900441-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence That 3-Phosphoinositide-dependent Protein Kinase-1 Mediates Phosphorylation of p70 S6 Kinasein Vivoat Thr-412 as well as Thr-252
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900441-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanism of activation and function of protein kinase B.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900441-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rapamycin suppresses 5'TOP mRNA translation through inhibition of p70s6k.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900441-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitogen inactivation of glycogen synthase kinase-3 beta in intact cells via serine 9 phosphorylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900441-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of protein kinase B and the MAP kinase cascade in mediating the EGF-dependent inhibition of glycogen synthase kinase 3 in Swiss 3T3 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900441-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The AMP-activated protein kinase--fuel gauge of the mammalian cell?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900441-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of the AMP-activated protein kinase in the cellular stress response
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900441-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PDK1 homologs activate the Pkc1-mitogen-activated protein kinase pathway in yeast
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900441-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional counterparts of mammalian protein kinases PDK1 and SGK in budding yeast
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900441-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A Schizosaccharomyces pombe gene, ksg1, that shows structural homology to the human phosphoinositide-dependent protein kinase PDK1, is essential for growth, mating and sporulation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900441-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Modulation of insulin receptor substrate-1 tyrosine phosphorylation by an Akt/phosphatidylinositol 3-kinase pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900441-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a pocket in the PDK1 kinase domain that interacts with PIF and the C-terminal residues of PKA
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900441-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900441-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900441-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
EGF induced SOS phosphorylation in PC12 cells involves P90 RSK-2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900441-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation and regulation of Raf by Akt (protein kinase B)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900441-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Akt, a pleckstrin homology domain containing kinase, is activated primarily by phosphorylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900441-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0960-9822(00)00441-3
1 reference
stated in
Europe PubMed Central
PubMed ID
10801415
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10801415%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
PubMed ID
10801415
1 reference
stated in
Europe PubMed Central
PubMed ID
10801415
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10801415%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
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