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Neurotrophin 3
mammalian protein found in Rattus norvegicus
neurotrophic factor
NGF-2
neurotrophin-3
NT-3
neurotrophin-3 (HDNF/NT-3)
HDNF
Ntf3
nerve growth factor 2
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P18280
subclass of
protein
1 reference
stated in
UniProt
retrieved
19 January 2017
UniProt protein ID
P18280
part of
Cystine-knot cytokine
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P18280
Neurotrophin-3
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P18280
Nerve growth factor-related, protein family
1 reference
based on heuristic
inferred from protein domain or family
Nerve growth factor conserved site, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
brown rat
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P18280
encoded by
Ntf3
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P18280
molecular function
signaling receptor binding
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18280
determination method
IEA
neurotrophin receptor binding
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18280
determination method
IEA
growth factor activity
determination method
IBA
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P18280
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18280
determination method
IEA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18280
determination method
IBA
nerve growth factor binding
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Molecular cloning and neurotrophic activities of a protein with structural similarities to nerve growth factor: developmental and topographical expression in the brain
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18280
determination method
IMP
cell component
extracellular region
determination method
IEA
TAS
2 references
retrieved
14 February 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18280
determination method
TAS
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P18280
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18280
determination method
IEA
extracellular space
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18280
determination method
IBA
synaptic vesicle
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18280
determination method
IBA
axon
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18280
determination method
IBA
dendrite
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18280
determination method
IBA
cytoplasmic vesicle
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18280
determination method
IBA
biological process
transmembrane receptor protein tyrosine kinase signaling pathway
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18280
determination method
IBA
nervous system development
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Molecular cloning and neurotrophic activities of a protein with structural similarities to nerve growth factor: developmental and topographical expression in the brain
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18280
determination method
IMP
peripheral nervous system development
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18280
determination method
IBA
memory
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18280
determination method
IBA
regulation of signaling receptor activity
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18280
determination method
IEA
nerve development
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18280
determination method
IBA
nerve growth factor signaling pathway
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18280
determination method
IBA
myelination
determination method
IDA
1 reference
retrieved
14 February 2019
stated in
In vitro myelination by oligodendrocyte precursor cells transfected with the neurotrophin-3 gene
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18280
determination method
IDA
negative regulation of neuron apoptotic process
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18280
determination method
IBA
regulation of neuron differentiation
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18280
determination method
IBA
positive regulation of glial cell differentiation
determination method
IDA
1 reference
retrieved
14 February 2019
stated in
In vitro myelination by oligodendrocyte precursor cells transfected with the neurotrophin-3 gene
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18280
determination method
IDA
neuron projection morphogenesis
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18280
determination method
IBA
modulation of chemical synaptic transmission
determination method
IBA
IDA
2 references
retrieved
14 February 2019
stated in
Chronic Neurotrophin-3 Strengthens Synaptic Connections to Motoneurons in the Neonatal Rat
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18280
determination method
IDA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18280
determination method
IBA
has part(s)
Nerve growth factor-related
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P18280
Nerve growth factor conserved site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P18280
Identifiers
RefSeq protein ID
NP_001257797
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
81737
NP_001257798
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
81737
NP_001257799
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
81737
NP_112335
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
81737
UniProt protein ID
P18280
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P18280
Ensembl protein ID
ENSRNOP00000026685
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSRNOP00000026685
ENSRNOP00000069580
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSRNOP00000069580
ENSRNOP00000070420
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSRNOP00000070420
ENSRNOP00000090293
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSRNOP00000090293
Sitelinks
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Multilingual sites
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