(Q28558525)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

14 February 2019

Association of HAP1 isoforms with a unique cytoplasmic structure

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

14 February 2019

Huntingtin phosphorylation acts as a molecular switch for anterograde/retrograde transport in neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

14 February 2019

Huntingtin-associated protein 1 (HAP1) interacts with the p150Glued subunit of dynactin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

14 February 2019

14-3-3 protein interacts with Huntingtin-associated protein 1 and regulates its trafficking

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

14 February 2019

Huntingtin-associated protein 1 (HAP1) binds to a Trio-like polypeptide, with a rac1 guanine nucleotide exchange factor domain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

protein domain specific binding

1 reference

14 February 2019

Huntingtin and huntingtin-associated protein 1 influence neuronal calcium signaling mediated by inositol-(1,4,5) triphosphate receptor type 1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

transmembrane transporter binding

IPI

1 reference

14 February 2019

Huntingtin and huntingtin-associated protein 1 influence neuronal calcium signaling mediated by inositol-(1,4,5) triphosphate receptor type 1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

brain-derived neurotrophic factor binding

2 references

14 February 2019

Huntingtin-associated protein-1 interacts with pro-brain-derived neurotrophic factor and mediates its transport and release

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

14 February 2019

Precursor of brain-derived neurotrophic factor (proBDNF) forms a complex with Huntingtin-associated protein-1 (HAP1) and sortilin that modulates proBDNF trafficking, degradation, and processing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

1 reference

14 February 2019

Huntingtin-associated protein 1 interacts with hepatocyte growth factor-regulated tyrosine kinase substrate and functions in endosomal trafficking

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

1 reference

14 February 2019

Huntingtin-associated protein 1 interacts with hepatocyte growth factor-regulated tyrosine kinase substrate and functions in endosomal trafficking

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

endoplasmic reticulum

1 reference

14 February 2019

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

1 reference

14 February 2019

Expression of huntingtin-associated protein-1 in neuronal cells implicates a role in neuritic growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

1 reference

14 February 2019

Expression of huntingtin-associated protein-1 in neuronal cells implicates a role in neuritic growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

1 reference

14 February 2019

Expression of huntingtin-associated protein-1 in neuronal cells implicates a role in neuritic growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

perinuclear region of cytoplasm

1 reference

14 February 2019

Expression of huntingtin-associated protein-1 in neuronal cells implicates a role in neuritic growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

1 reference

14 February 2019

The cellular and subcellular localization of huntingtin-associated protein 1 (HAP1): comparison with huntingtin in rat and human.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

1 reference

14 February 2019

The cellular and subcellular localization of huntingtin-associated protein 1 (HAP1): comparison with huntingtin in rat and human.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

anterograde axonal transport

3 references

14 February 2019

Huntingtin-associated protein-1 interacts with pro-brain-derived neurotrophic factor and mediates its transport and release

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

14 February 2019

Huntingtin associated protein 1 regulates trafficking of the amyloid precursor protein and modulates amyloid beta levels in neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

retrograde axonal transport

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

positive regulation of neuron projection development

1 reference

14 February 2019

Expression of huntingtin-associated protein-1 in neuronal cells implicates a role in neuritic growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

regulation of exocytosis

1 reference

14 February 2019

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

cell projection organization

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity

1 reference

14 February 2019

Huntingtin and huntingtin-associated protein 1 influence neuronal calcium signaling mediated by inositol-(1,4,5) triphosphate receptor type 1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

positive regulation of synaptic transmission, GABAergic

positive regulation of neurotrophin production

IMP

2 references

14 February 2019

Huntingtin-associated protein-1 interacts with pro-brain-derived neurotrophic factor and mediates its transport and release

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

14 February 2019

Precursor of brain-derived neurotrophic factor (proBDNF) forms a complex with Huntingtin-associated protein-1 (HAP1) and sortilin that modulates proBDNF trafficking, degradation, and processing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

early endosome to late endosome transport

1 reference

14 February 2019

Huntingtin-associated protein 1 interacts with hepatocyte growth factor-regulated tyrosine kinase substrate and functions in endosomal trafficking

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

positive regulation of epidermal growth factor receptor signaling pathway

TAS

1 reference

14 February 2019

Lack of huntingtin-associated protein-1 causes neuronal death resembling hypothalamic degeneration in Huntington's disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

vesicle transport along microtubule

IMP

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

mitochondrion distribution

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

cellular response to growth factor stimulus

1 reference

14 February 2019

Expression of huntingtin-associated protein-1 in neuronal cells implicates a role in neuritic growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

anterograde axonal transport of mitochondrion

IEP

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

regulation of postsynaptic neurotransmitter receptor internalization

EXP

negative regulation of amyloid-beta formation

1 reference

14 February 2019

Huntingtin associated protein 1 regulates trafficking of the amyloid precursor protein and modulates amyloid beta levels in neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

regulation of organelle transport along microtubule

IMP

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

positive regulation of non-motile cilium assembly

ISS

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54256

1 reference

InterPro Release 71.0