(Q28559401)

http://www.ebi.ac.uk/interpro/protein/P05182

Cytochrome P450, E-class, group I, CYP2E-like

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P05182

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

cytochrome P450, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

17 November 2021

1 reference

17 November 2021

monooxygenase activity

3 references

14 February 2019

Increased cytochrome P-450 2E1 expression sensitizes hepatocytes to c-Jun-mediated cell death from TNF-alpha

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05182

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05182

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05182

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05182

arachidonic acid epoxygenase activity

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05182

steroid hydroxylase activity

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05182

1 reference

14 February 2019

Enzyme-specific transport of rat liver cytochrome P450 to the Golgi apparatus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05182

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

IC

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05182

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05182

14 February 2019

Enzyme-specific transport of rat liver cytochrome P450 to the Golgi apparatus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05182

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05182

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05182

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05182

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05182

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05182

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05182

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05182

Mitochondrial targeting of cytochrome P450 proteins containing NH2-terminal chimeric signals involves an unusual TOM20/TOM22 bypass mechanism

Hsp70 protein binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05182

Mitochondrial targeting of cytochrome P450 proteins containing NH2-terminal chimeric signals involves an unusual TOM20/TOM22 bypass mechanism

Hsp90 protein binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05182

1 reference

14 February 2019

Enzyme-specific transport of rat liver cytochrome P450 to the Golgi apparatus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05182

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05182

1 reference

14 January 2019

Ethanol increases mitochondrial cytochrome P450 2E1 in mouse liver and rat hepatocytes

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05182&geneProductId=UniProtKB:P05182

endoplasmic reticulum

endoplasmic reticulum membrane

2 references

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05182&geneProductId=UniProtKB:P05182

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05182

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05182

intrinsic component of endoplasmic reticulum membrane

1 reference

14 February 2019

Identification of sequences responsible for intracellular targeting and membrane binding of rat CYP2E1 in yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05182

intracellular membrane-bounded organelle

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05182

14 February 2019

Expression of P450 enzymes in rat whole skin and cultured epidermal keratinocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05182

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05182

mitochondrial inner membrane

1 reference

14 January 2019

Mitochondrial targeting of cytochrome P450 proteins containing NH2-terminal chimeric signals involves an unusual TOM20/TOM22 bypass mechanism

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05182&geneProductId=UniProtKB:P05182

organic acid metabolic process

biological process

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05182

triglyceride metabolic process

1 reference

14 February 2019

The role of ethanol metabolism in development of alcoholic steatohepatitis in the rat

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05182

xenobiotic metabolic process

IMP

3 references

14 February 2019

Expression of P450 enzymes in rat whole skin and cultured epidermal keratinocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05182

14 February 2019

Identification of rat cytochromes P450 metabolizing N-(2-methoxyphenyl)hydroxylamine, a human metabolite of the environmental pollutants and carcinogens o-anisidine and o-nitroanisole

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05182

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05182

steroid metabolic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05182

response to bacterium

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05182

1 reference

14 February 2019

Cytochrome P450 2E1 in rat tracheobronchial airways: response to ozone exposure

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05182

response to organonitrogen compound

IEP

1 reference

14 February 2019

Effect of taurine supplementation on cytochrome P450 2E1 and oxidative stress in the liver and kidneys of rats with streptozotocin-induced diabetes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05182

monoterpenoid metabolic process

IEP

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05182

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

epoxygenase P450 pathway

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05182

1 reference

14 February 2019

Ethanol increases mitochondrial cytochrome P450 2E1 in mouse liver and rat hepatocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05182

heterocycle metabolic process

IEP

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05182

cytochrome P450, conserved site

has part(s)

1 reference

stated in

InterPro Release 71.0