(Q28559464)

English

Myostatin

mammalian protein found in Rattus norvegicus

GDF-8
growth/differentiation factor 8
Mstn

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

Cystine-knot cytokine

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O35312

growth/differentiation factor 8

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O35312

Transforming growth factor-beta, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

TGF-beta, propeptide family

1 reference

based on heuristic

inferred from protein domain or family

Transforming growth factor beta, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

molecular function

determination method

1 reference

14 February 2019

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35312

determination method

signaling receptor binding

determination method

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35312

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35312

determination method

transforming growth factor beta receptor binding

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35312

determination method

growth factor activity

determination method

2 references

heparin binding

determination method

2 references

identical protein binding

determination method

2 references

protein homodimerization activity

determination method

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35312

determination method

extracellular region

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35312

determination method

extracellular space

determination method

4 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35312

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35312

determination method

14 February 2019

Role of serum myostatin during the lactation period

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35312

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35312

determination method

determination method

1 reference

14 February 2019

Spatiotemporal expression of decorin and myostatin during rat skeletal muscle development

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35312

determination method

biological process

transforming growth factor beta receptor signaling pathway

determination method

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35312

determination method

response to heat

determination method

1 reference

14 February 2019

Regulation of myostatin by glucocorticoids after thermal injury

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35312

determination method

response to gravity

determination method

1 reference

14 February 2019

Myostatin and insulin-like growth factor-I and -II expression in the muscle of rats exposed to the microgravity environment of the NeuroLab space shuttle flight

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35312

determination method

regulation of signaling receptor activity

determination method

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35312

determination method

positive regulation of pathway-restricted SMAD protein phosphorylation

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35312

determination method

skeletal muscle atrophy

determination method

1 reference

14 February 2019

Myostatin expression in age and denervation-induced skeletal muscle atrophy

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35312

determination method

negative regulation of muscle hypertrophy

determination method

1 reference

14 February 2019

Myostatin short interfering hairpin RNA gene transfer increases skeletal muscle mass

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35312

determination method

response to muscle activity

determination method

1 reference

14 February 2019

Short-term endurance training results in a muscle-specific decrease of myostatin mRNA content in the rat

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35312

determination method

ovulation cycle process

determination method

1 reference

14 February 2019

Presence, actions, and regulation of myostatin in rat uterus and myometrial cells

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35312

determination method

response to testosterone

determination method

1 reference

14 February 2019

Muscle expressions of MGF, IGF-IEa, and myostatin in intact and hypophysectomized rats: effects of rhGH and testosterone alone or combined

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35312

determination method

negative regulation of kinase activity

determination method

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35312

determination method

regulation of apoptotic process

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35312

determination method

skeletal muscle tissue regeneration

determination method

1 reference

14 February 2019

Myostatin levels in regenerating rat muscles and in myogenic cell cultures

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35312

determination method

regulation of MAPK cascade

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35312

determination method

response to estrogen

determination method

1 reference

14 February 2019

Presence, actions, and regulation of myostatin in rat uterus and myometrial cells

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35312

determination method

response to ethanol

determination method

1 reference

14 February 2019

IGF-I/IGFBP-3 ameliorates alterations in protein synthesis, eIF4E availability, and myostatin in alcohol-fed rats

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35312

determination method

negative regulation of myoblast differentiation

determination method

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35312

determination method

positive regulation of transcription, DNA-templated

determination method

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35312

determination method

negative regulation of insulin receptor signaling pathway

determination method

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35312

determination method

muscle cell cellular homeostasis

determination method

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35312

determination method

cell development

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35312

determination method

response to glucocorticoid

determination method

1 reference

14 February 2019

The effect of glutamine on prevention of glucocorticoid-induced skeletal muscle atrophy is associated with myostatin suppression

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35312

determination method

response to electrical stimulus

determination method

1 reference

14 February 2019

Muscle and nerve responses after different intervals of electrical stimulation sessions on denervated rat muscle

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35312

determination method

negative regulation of protein kinase B signaling

determination method

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35312

determination method

SMAD protein signal transduction

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35312

determination method

cellular response to dexamethasone stimulus

determination method

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35312

determination method

negative regulation of skeletal muscle satellite cell proliferation

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35312

determination method

negative regulation of satellite cell differentiation

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35312

determination method

negative regulation of myoblast proliferation

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35312

determination method

TGF-beta, propeptide

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O35312

Transforming growth factor-beta, C-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O35312

Transforming growth factor beta, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O35312

Identifiers

RefSeq protein ID

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSRNOP00000038159

1 reference

ensembl Release 106

Ensembl protein ID

ENSRNOP00000038159

Sitelinks

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Multilingual sites(0 entries)

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