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DNA-damage-inducible transcript 4
mammalian protein found in Rattus norvegicus
protein regulated in development and DNA damage response 1
HIF-1 responsive protein RTP801
REDD-1
DNA damage-inducible transcript 4 protein
HIF-1 responsive RTP801
Ddit4
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q8VHZ9
subclass of
protein
1 reference
stated in
UniProt
retrieved
19 January 2017
UniProt protein ID
Q8VHZ9
part of
RTP801-like
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8VHZ9
RTP801-like, C-terminal domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8VHZ9
found in taxon
brown rat
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q8VHZ9
encoded by
Ddit4
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q8VHZ9
molecular function
14-3-3 protein binding
determination method
IBA
1 reference
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VHZ9
determination method
IBA
cell component
cytoplasm
determination method
IEA
ISS
3 references
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8VHZ9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VHZ9
determination method
ISS
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8VHZ9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VHZ9
determination method
IEA
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VHZ9
determination method
IEA
mitochondrion
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8VHZ9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VHZ9
determination method
IEA
cytosol
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8VHZ9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VHZ9
determination method
IEA
biological process
response to hypoxia
determination method
IDA
1 reference
retrieved
14 February 2019
stated in
Identification of a novel hypoxia-inducible factor 1-responsive gene, RTP801, involved in apoptosis.
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VHZ9
determination method
IDA
neuron migration
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
RTP801/REDD1 regulates the timing of cortical neurogenesis and neuron migration
GOA
curator
UniProt
UniProt protein ID
Q8VHZ9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VHZ9
determination method
IMP
apoptotic process
determination method
IDA
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8VHZ9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VHZ9
determination method
IEA
retrieved
14 February 2019
stated in
Identification of a novel hypoxia-inducible factor 1-responsive gene, RTP801, involved in apoptosis.
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VHZ9
determination method
IDA
brain development
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
RTP801/REDD1 regulates the timing of cortical neurogenesis and neuron migration
GOA
curator
UniProt
UniProt protein ID
Q8VHZ9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VHZ9
determination method
IMP
cell population proliferation
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
RTP801/REDD1 regulates the timing of cortical neurogenesis and neuron migration
GOA
curator
UniProt
UniProt protein ID
Q8VHZ9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VHZ9
determination method
IMP
negative regulation of signal transduction
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VHZ9
determination method
IEA
negative regulation of peptidyl-threonine phosphorylation
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
RTP801 is induced in Parkinson's disease and mediates neuron death by inhibiting Akt phosphorylation/activation
GOA
curator
UniProt
UniProt protein ID
Q8VHZ9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VHZ9
determination method
IMP
neuron differentiation
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
RTP801/REDD1 regulates the timing of cortical neurogenesis and neuron migration
GOA
curator
UniProt
UniProt protein ID
Q8VHZ9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VHZ9
determination method
IMP
negative regulation of TOR signaling
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
RTP801/REDD1 regulates the timing of cortical neurogenesis and neuron migration
GOA
curator
UniProt
UniProt protein ID
Q8VHZ9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VHZ9
determination method
IMP
negative regulation of peptidyl-serine phosphorylation
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
RTP801 is induced in Parkinson's disease and mediates neuron death by inhibiting Akt phosphorylation/activation
GOA
curator
UniProt
UniProt protein ID
Q8VHZ9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VHZ9
determination method
IMP
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
determination method
ISS
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8VHZ9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VHZ9
determination method
ISS
neurotrophin TRK receptor signaling pathway
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
RTP801/REDD1 regulates the timing of cortical neurogenesis and neuron migration
GOA
curator
UniProt
UniProt protein ID
Q8VHZ9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VHZ9
determination method
IMP
defense response to virus
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8VHZ9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VHZ9
determination method
IEA
positive regulation of neuron death
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
RTP801 is induced in Parkinson's disease and mediates neuron death by inhibiting Akt phosphorylation/activation
GOA
curator
UniProt
UniProt protein ID
Q8VHZ9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VHZ9
determination method
IMP
negative regulation of intracellular signal transduction
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
RTP801 is induced in Parkinson's disease and mediates neuron death by inhibiting Akt phosphorylation/activation
GOA
curator
UniProt
UniProt protein ID
Q8VHZ9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VHZ9
determination method
IMP
response to hypoxia
determination method
IBA
IDA
2 references
retrieved
9 May 2019
stated in
Identification of a novel hypoxia-inducible factor 1-responsive gene, RTP801, involved in apoptosis.
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VHZ9
determination method
IDA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VHZ9
determination method
IBA
apoptotic process
determination method
IBA
IDA
IEA
3 references
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8VHZ9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VHZ9
determination method
IEA
retrieved
9 May 2019
stated in
Identification of a novel hypoxia-inducible factor 1-responsive gene, RTP801, involved in apoptosis.
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VHZ9
determination method
IDA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VHZ9
determination method
IBA
regulation of TOR signaling
determination method
IBA
1 reference
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VHZ9
determination method
IBA
negative regulation of TOR signaling
determination method
IBA
IMP
2 references
retrieved
9 May 2019
stated in
RTP801/REDD1 regulates the timing of cortical neurogenesis and neuron migration
GOA
curator
UniProt
UniProt protein ID
Q8VHZ9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VHZ9
determination method
IMP
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VHZ9
determination method
IBA
Identifiers
RefSeq protein ID
NP_543182
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
140942
UniProt protein ID
Q8VHZ9
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q8VHZ9
Ensembl protein ID
ENSRNOP00000073198
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSRNOP00000073198
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