(Q28560450)

http://www.ebi.ac.uk/interpro/protein/Q9QYH7

Motilin/ghrelin-associated peptide family

1 reference

based on heuristic

inferred from protein domain or family

Motilin/ghrelin, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

G protein-coupled receptor binding

1 reference

14 February 2019

Ghrelin is a growth-hormone-releasing acylated peptide from stomach

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

growth hormone-releasing hormone activity

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

14 February 2019

Ghrelin is a growth-hormone-releasing acylated peptide from stomach

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

14 February 2019

Central effects of ghrelin on serum growth hormone and morphology of pituitary somatotropes in rats

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

14 February 2019

Ghrelin is a growth-hormone-releasing acylated peptide from stomach

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

2 references

Schaffer collateral - CA1 synapse

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

Ghrelin promotes reorganization of dendritic spines in cultured rat hippocampal slices

glutamatergic synapse

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

14 February 2019

Involvement of PKA and ERK pathways in ghrelin-induced long-lasting potentiation of excitatory synaptic transmission in the CA1 area of rat hippocampus.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

14 February 2019

Ghrelin promotes reorganization of dendritic spines in cultured rat hippocampal slices

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

14 February 2019

Involvement of PKA and ERK pathways in ghrelin-induced long-lasting potentiation of excitatory synaptic transmission in the CA1 area of rat hippocampus.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

G protein-coupled receptor signaling pathway

EXP

biological process

1 reference

14 February 2019

Ghrelin is a growth-hormone-releasing acylated peptide from stomach

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

positive regulation of cytosolic calcium ion concentration

1 reference

14 February 2019

Ghrelin is present in pancreatic alpha-cells of humans and rats and stimulates insulin secretion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

HUGO Gene Nomenclature Committee

adult feeding behavior

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

2 references

regulation of signaling receptor activity

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

response to nutrient levels

1 reference

14 February 2019

Obesity in MENX Rats Is Accompanied by High Circulating Levels of Ghrelin and Improved Insulin Sensitivity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

positive regulation of insulin secretion

IEP

1 reference

14 February 2019

Ghrelin is present in pancreatic alpha-cells of humans and rats and stimulates insulin secretion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

positive regulation of response to food

1 reference

14 February 2019

Ghrelin attenuates the inhibitory effects of glucagon-like peptide-1 and peptide YY(3-36) on food intake and gastric emptying in rats

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

positive regulation of appetite

3 references

14 February 2019

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

14 February 2019

Anti-ghrelin Spiegelmer NOX-B11 inhibits neurostimulatory and orexigenic effects of peripheral ghrelin in rats

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

negative regulation of interleukin-1 beta production

3 references

1 reference

14 February 2019

Comparison of the gastroprokinetic effects of ghrelin, GHRP-6 and motilin in rats in vivo and in vitro.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

positive regulation of insulin secretion involved in cellular response to glucose stimulus

1 reference

14 February 2019

Unacylated ghrelin is active on the INS-1E rat insulinoma cell line independently of the growth hormone secretagogue receptor type 1a and the corticotropin releasing factor 2 receptor.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

positive regulation of growth rate

1 reference

14 February 2019

Influence of ghrelin on gastric and duodenal growth and expression of digestive enzymes in young mature rats.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

negative regulation of locomotion

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

negative regulation of circadian sleep/wake cycle, REM sleep

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

negative regulation of apoptotic process

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

14 February 2019

Ghrelin inhibits apoptosis signal-regulating kinase 1 activity via upregulating heat-shock protein 70

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

2 references

positive regulation of growth

1 reference

14 February 2019

Pattern-dependent suppression of growth hormone (GH) pulsatility by ghrelin and GH-releasing peptide-6 in moderately GH-deficient rats.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

positive regulation of circadian sleep/wake cycle, non-REM sleep

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

2 references

negative regulation of inflammatory response

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

positive regulation of corticotropin secretion

IBA

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

positive regulation of cortisol secretion

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

response to electrical stimulus

1 reference

14 February 2019

Effects of ghrelin on gastric distension sensitive neurons and gastric motility in the lateral septum and arcuate nucleus regulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

positive regulation of synapse assembly

IEP

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

regulation of transmission of nerve impulse

1 reference

14 February 2019

Effects of ghrelin on gastric distension sensitive neurons and gastric motility in the lateral septum and arcuate nucleus regulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

excitatory postsynaptic potential

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

positive regulation of growth hormone secretion

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

14 February 2019

Ghrelin is a growth-hormone-releasing acylated peptide from stomach

GOA

curator

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

positive regulation of protein tyrosine kinase activity

IBA

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

postsynaptic modulation of chemical synaptic transmission

EXP

positive regulation of small intestinal transit

1 reference

14 February 2019

Down-regulation of ghrelin receptors in the small intestine delays small intestinal transit in vagotomized rats

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

positive regulation of bone development

1 reference

14 February 2019

Pattern-dependent suppression of growth hormone (GH) pulsatility by ghrelin and GH-releasing peptide-6 in moderately GH-deficient rats.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

positive regulation of sprouting angiogenesis

1 reference

14 February 2019

Ghrelin modulates physiologic and pathologic retinal angiogenesis through GHSR-1a

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

positive regulation of eating behavior

1 reference

14 February 2019

Ghrelin and des-octanoyl ghrelin promote adipogenesis directly in vivo by a mechanism independent of the type 1a growth hormone secretagogue receptor.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

positive regulation of adipose tissue development

1 reference

14 February 2019

Ghrelin and des-octanoyl ghrelin promote adipogenesis directly in vivo by a mechanism independent of the type 1a growth hormone secretagogue receptor.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

positive regulation of gastro-intestinal system smooth muscle contraction

1 reference

14 February 2019

Comparison of the gastroprokinetic effects of ghrelin, GHRP-6 and motilin in rats in vivo and in vitro.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

positive regulation of gastric mucosal blood circulation

1 reference

14 February 2019

Influence of ghrelin on gastric and duodenal growth and expression of digestive enzymes in young mature rats.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

positive regulation of small intestine smooth muscle contraction

regulation of gastric motility

1 reference

14 February 2019

Effects of ghrelin on gastric distension sensitive neurons and gastric motility in the lateral septum and arcuate nucleus regulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

positive regulation of vascular endothelial cell proliferation

1 reference

14 February 2019

Ghrelin modulates physiologic and pathologic retinal angiogenesis through GHSR-1a

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

positive regulation of feeding behavior

1 reference

14 February 2019

Influence of ghrelin on gastric and duodenal growth and expression of digestive enzymes in young mature rats.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7

Motilin/ghrelin-associated peptide

has part(s)

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9QYH7

Motilin/ghrelin

1 reference

stated in

InterPro Release 71.0