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Matrix metallopeptidase 8
mammalian protein found in Rattus norvegicus
Mmp8
matrix metalloproteinase-8
neutrophil collagenease
MMP-8
neutrophil collagenase
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
O88766
subclass of
protein
1 reference
stated in
UniProt
retrieved
19 January 2017
UniProt protein ID
O88766
part of
Hemopexin-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/O88766
Metallopeptidase, catalytic domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/O88766
PGBD-like superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/O88766
Peptidase M10A, catalytic domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Hemopexin-like domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Peptidase, metallopeptidase family
1 reference
based on heuristic
inferred from protein domain or family
Peptidase M10, metallopeptidase family
1 reference
based on heuristic
inferred from protein domain or family
Peptidoglycan binding-like, protein family
1 reference
based on heuristic
inferred from protein domain or family
Peptidase M10A, cysteine switch, zinc binding site, protein family
1 reference
based on heuristic
inferred from protein domain or family
Hemopexin, conserved site, protein family
1 reference
based on heuristic
inferred from protein domain or family
Hemopexin-like repeats, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
brown rat
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
O88766
encoded by
Mmp8
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
O88766
molecular function
metalloendopeptidase activity
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O88766&geneProductId=UniProtKB:O88766
determination method
IEA
serine-type endopeptidase activity
determination method
ISS
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O88766
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88766
determination method
ISS
calcium ion binding
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Repair after cholestatic liver injury correlates with neutrophil infiltration and matrix metalloproteinase 8 activity
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88766
determination method
IMP
peptidase activity
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O88766
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88766
determination method
IEA
metallopeptidase activity
determination method
IDA
IEA
3 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O88766
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88766
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88766
determination method
IEA
retrieved
14 February 2019
stated in
Repair after cholestatic liver injury correlates with neutrophil infiltration and matrix metalloproteinase 8 activity
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88766
determination method
IDA
zinc ion binding
determination method
IEA
IMP
2 references
retrieved
14 February 2019
stated in
Repair after cholestatic liver injury correlates with neutrophil infiltration and matrix metalloproteinase 8 activity
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88766
determination method
IMP
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88766
determination method
IEA
hydrolase activity
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O88766
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88766
determination method
IEA
metal ion binding
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O88766
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88766
determination method
IEA
metalloendopeptidase activity
determination method
IBA
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88766
determination method
IEA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88766
determination method
IBA
cell component
extracellular region
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O88766
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88766
determination method
IEA
extracellular space
determination method
IBA
IDA
ISS
3 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O88766
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88766
determination method
ISS
retrieved
14 February 2019
stated in
Up-regulation of trypsin and mesenchymal MMP-8 during development of hyperoxic lung injury in the rat
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88766
determination method
IDA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88766
determination method
IBA
extracellular matrix
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88766
determination method
IEA
biological process
ossification
determination method
IEP
1 reference
retrieved
14 February 2019
stated in
Osteoblasts and osteocytes express MMP2 and -8 and TIMP1, -2, and -3 along with extracellular matrix molecules during appositional bone formation
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88766
determination method
IEP
proteolysis
determination method
IDA
IEA
ISS
4 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O88766
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88766
determination method
ISS
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O88766
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88766
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88766
determination method
IEA
retrieved
14 February 2019
stated in
Repair after cholestatic liver injury correlates with neutrophil infiltration and matrix metalloproteinase 8 activity
GOA
curator
Rat genome database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88766
determination method
IDA
collagen catabolic process
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
O88766
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O88766&geneProductId=UniProtKB:O88766
determination method
IEA
positive regulation of nitric oxide biosynthetic process
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Matrix metalloproteinase-8 plays a pivotal role in neuroinflammation by modulating TNF-α activation.
GOA
curator
ARUK-UCL
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88766
determination method
IMP
positive regulation of neuroinflammatory response
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Matrix metalloproteinase-8 plays a pivotal role in neuroinflammation by modulating TNF-α activation.
GOA
curator
ARUK-UCL
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88766
determination method
IMP
extracellular matrix organization
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88766
determination method
IBA
collagen catabolic process
determination method
IBA
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O88766
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88766
determination method
IEA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88766
determination method
IBA
has part(s)
Peptidase M10A, cysteine switch, zinc binding site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/O88766
Hemopexin-like domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/O88766
Peptidase M10, metallopeptidase
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/O88766
Peptidase, metallopeptidase
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/O88766
Peptidase M10A, catalytic domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/O88766
Peptidoglycan binding-like
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/O88766
Hemopexin, conserved site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/O88766
Hemopexin-like repeats
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/O88766
Identifiers
RefSeq protein ID
NP_071557
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
63849
UniProt protein ID
O88766
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
O88766
Ensembl protein ID
ENSRNOP00000013936
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSRNOP00000013936
Sitelinks
Wikipedia
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Wikinews
(0 entries)
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Wikiquote
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Wikisource
(0 entries)
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Wikiversity
(0 entries)
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Wikivoyage
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Wiktionary
(0 entries)
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Multilingual sites
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