(Q28561868)

double-stranded methylated DNA binding

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

14 February 2019

Structure-specific binding of MeCP2 to four-way junction DNA through its methyl CpG-binding domain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

14 February 2019

MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

1 reference

14 February 2019

Methyl-CpG-binding protein, MeCP2, is a target molecule for maintenance DNA methyltransferase, Dnmt1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

protein domain specific binding

IPI

1 reference

14 February 2019

MeCP2 suppresses nuclear microRNA processing and dendritic growth by regulating the DGCR8/Drosha complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin

IPI

chromatin DNA binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

Structure-specific binding of MeCP2 to four-way junction DNA through its methyl CpG-binding domain

unmethylated CpG binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

promoter-specific chromatin binding

1 reference

14 February 2019

IUGR differentially alters MeCP2 expression and H3K9Me3 of the PPARγ gene in male and female rat lungs during alveolarization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

14 February 2019

Phosphorylation of methyl-CpG binding protein 2 (MeCP2) regulates the intracellular localization during neuronal cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

Dendritic spine pathologies in hippocampal pyramidal neurons from Rett syndrome brain and after expression of Rett-associated MECP2 mutations

TAS

glutamatergic synapse

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

14 February 2019

Dendritic spine pathologies in hippocampal pyramidal neurons from Rett syndrome brain and after expression of Rett-associated MECP2 mutations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

14 February 2019

Dendritic spine pathologies in hippocampal pyramidal neurons from Rett syndrome brain and after expression of Rett-associated MECP2 mutations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

negative regulation of transcription by RNA polymerase II

EXP

biological process

4 references

14 February 2019

MeCP2 suppresses nuclear microRNA processing and dendritic growth by regulating the DGCR8/Drosha complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

14 February 2019

MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

1 reference

14 February 2019

Epigenetic regulation of neonatal cardiomyocytes differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

response to radiation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

response to ionizing radiation

IBA

1 reference

14 February 2019

Radiation-induced molecular changes in rat mammary tissue: possible implications for radiation-induced carcinogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

1 reference

14 February 2019

Influence of developmental lead exposure on expression of DNA methyltransferases and methyl cytosine-binding proteins in hippocampus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

positive regulation of gene expression

1 reference

14 February 2019

MeCP2 suppresses nuclear microRNA processing and dendritic growth by regulating the DGCR8/Drosha complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

negative regulation of gene expression

1 reference

14 February 2019

Bdnf overexpression in hippocampal neurons prevents dendritic atrophy caused by Rett-associated MECP2 mutations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

oligodendrocyte development

1 reference

14 February 2019

Involvement of MeCP2 in Regulation of Myelin-Related Gene Expression in Cultured Rat Oligodendrocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

response to organic cyclic compound

1 reference

14 February 2019

Neonatal exposure to estradiol/bisphenol A alters promoter methylation and expression of Nsbp1 and Hpcal1 genes and transcriptional programs of Dnmt3a/b and Mbd2/4 in the rat prostate gland throughout life

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

The expression of methyl CpG binding factor MeCP2 correlates with cellular differentiation in the developing rat brain and in cultured cells

spinal cord development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

Developmental expression of methyl-CpG binding protein 2 is dynamically regulated in the rodent brain

cerebellum development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

principal sensory nucleus of trigeminal nerve development

1 reference

14 February 2019

The expression of methyl CpG binding factor MeCP2 correlates with cellular differentiation in the developing rat brain and in cultured cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

1 reference

14 February 2019

The expression of methyl CpG binding factor MeCP2 correlates with cellular differentiation in the developing rat brain and in cultured cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

Developmental expression of methyl-CpG binding protein 2 is dynamically regulated in the rodent brain

hippocampus development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

olfactory bulb development

1 reference

14 February 2019

The expression of methyl CpG binding factor MeCP2 correlates with cellular differentiation in the developing rat brain and in cultured cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

1 reference

14 February 2019

The expression of methyl CpG binding factor MeCP2 correlates with cellular differentiation in the developing rat brain and in cultured cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

cerebral cortex development

1 reference

14 February 2019

Developmental expression of methyl-CpG binding protein 2 is dynamically regulated in the rodent brain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

The expression of methyl CpG binding factor MeCP2 correlates with cellular differentiation in the developing rat brain and in cultured cells

neuron differentiation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

positive regulation of synaptic plasticity

1 reference

14 February 2019

A critical and cell-autonomous role for MeCP2 in synaptic scaling up

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

negative regulation of protein binding

1 reference

14 February 2019

MeCP2 suppresses nuclear microRNA processing and dendritic growth by regulating the DGCR8/Drosha complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

Neonatal exposure to estradiol/bisphenol A alters promoter methylation and expression of Nsbp1 and Hpcal1 genes and transcriptional programs of Dnmt3a/b and Mbd2/4 in the rat prostate gland throughout life

response to estradiol

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

1 reference

14 February 2019

Mecp2 organizes juvenile social behavior in a sex-specific manner

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

cellular response to potassium ion

1 reference

14 February 2019

Derepression of BDNF Transcription Involves Calcium-Dependent Phosphorylation of MeCP2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

negative regulation of transcription, DNA-templated

1 reference

14 February 2019

MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

lung alveolus development

1 reference

14 February 2019

IUGR differentially alters MeCP2 expression and H3K9Me3 of the PPARγ gene in male and female rat lungs during alveolarization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

oligodendrocyte differentiation

1 reference

14 February 2019

A novel transcriptional regulator of myelin gene expression: implications for neurodevelopmental disorders

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

negative regulation of astrocyte differentiation

1 reference

14 February 2019

Methyl-CpG binding proteins are involved in restricting differentiation plasticity in neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

regulation of synapse organization

3 references

14 February 2019

Dendritic spine pathologies in hippocampal pyramidal neurons from Rett syndrome brain and after expression of Rett-associated MECP2 mutations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

14 February 2019

Dendritic spine pathologies in hippocampal pyramidal neurons from Rett syndrome brain and after expression of Rett-associated MECP2 mutations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

14 February 2019

Dendritic spine pathologies in hippocampal pyramidal neurons from Rett syndrome brain and after expression of Rett-associated MECP2 mutations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

positive regulation of dendritic spine development

EXP

1 reference

14 February 2019

SUMOylation of MeCP2 is essential for transcriptional repression and hippocampal synapse development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

negative regulation of dendritic spine development

1 reference

14 February 2019

MeCP2 suppresses nuclear microRNA processing and dendritic growth by regulating the DGCR8/Drosha complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

cellular response to isoquinoline alkaloid

1 reference

14 February 2019

The Rett syndrome protein MeCP2 regulates synaptic scaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

positive regulation of anterograde dense core granule transport

1 reference

14 February 2019

Modification of Mecp2 dosage alters axonal transport through the Huntingtin/Hap1 pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

positive regulation of retrograde dense core granule transport

1 reference

14 February 2019

Modification of Mecp2 dosage alters axonal transport through the Huntingtin/Hap1 pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

negative regulation of dendrite extension

1 reference

14 February 2019

MeCP2 suppresses nuclear microRNA processing and dendritic growth by regulating the DGCR8/Drosha complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

positive regulation of dendrite extension

1 reference

14 February 2019

Dendritic spine pathologies in hippocampal pyramidal neurons from Rett syndrome brain and after expression of Rett-associated MECP2 mutations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

positive regulation of branching morphogenesis of a nerve

1 reference

14 February 2019

Dendritic spine pathologies in hippocampal pyramidal neurons from Rett syndrome brain and after expression of Rett-associated MECP2 mutations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566

negative regulation of primary miRNA processing

1 reference

14 February 2019

MeCP2 suppresses nuclear microRNA processing and dendritic growth by regulating the DGCR8/Drosha complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00566