(Q28562749)

interleukin-1, type I receptor binding

1 reference

14 February 2019

Interleukin 1 receptor antagonist is a member of the interleukin 1 gene family: evolution of a cytokine control mechanism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25086

interleukin-1 receptor antagonist activity

TAS

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25086

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25086

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25086

14 February 2019

Interleukin-1 receptor antagonist as a modulator of gender differences in the febrile response to lipopolysaccharide in rats

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25086

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25086

1 reference

14 February 2019

Interleukin-1 mediates endothelin-1-induced fever and prostaglandin production in the preoptic area of rats

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25086

chronic inflammatory response to antigenic stimulus

1 reference

14 February 2019

Interleukin-1beta mediates the memory impairment associated with a delayed type hypersensitivity response to bacillus Calmette-Guérin in the rat hippocampus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25086

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25086

inflammatory response

1 reference

14 February 2019

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25086

1 reference

14 February 2019

Influence of Pregnancy on Plasma Cytokines and the Febrile Response to Intraperitoneal Administration of Bacterial Endotoxin in Rats

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25086

1 reference

14 February 2019

Interleukin-1beta mediates the memory impairment associated with a delayed type hypersensitivity response to bacillus Calmette-Guérin in the rat hippocampus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25086

negative regulation of signal transduction

1 reference

14 February 2019

Interleukin 1 receptor antagonist is a member of the interleukin 1 gene family: evolution of a cytokine control mechanism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25086

response to organonitrogen compound

TAS

1 reference

14 February 2019

The bisphosphonate alendronate improves the damage associated with trinitrobenzenesulfonic acid-induced colitis in rats

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25086

regulation of signaling receptor activity

1 reference

14 February 2019

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25086

negative regulation of glutamate secretion

IEA

1 reference

14 February 2019

Interleukin-1 receptor antagonist exerts agonist activity in the hippocampus independent of the interleukin-1 type I receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25086

response to organic cyclic compound

1 reference

14 February 2019

Rosiglitazone induces interleukin-1 receptor antagonist in interleukin-1beta-stimulated rat synovial fibroblasts via a peroxisome proliferator-activated receptor beta/delta-dependent mechanism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25086

1 reference

14 February 2019

Energy-sensing factors coactivator peroxisome proliferator-activated receptor γ coactivator 1-α (PGC-1α) and AMP-activated protein kinase control expression of inflammatory mediators in liver: induction of interleukin 1 receptor antagonist

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25086

cytokine-mediated signaling pathway

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25086

sensory perception of pain

1 reference

14 February 2019

Cytokine-mediated inflammatory hyperalgesia limited by interleukin-1 receptor antagonist

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25086

carboxylic acid metabolic process

1 reference

14 February 2019

Kainic acid induced expression of interleukin-1 receptor antagonist mRNA in the rat brain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25086

negative regulation of cell migration

1 reference

14 February 2019

Unmasking of LPA1 receptor-mediated migration response to lysophosphatidic acid by interleukin-1β-induced attenuation of Rho signaling pathways in rat astrocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25086

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

IDA

neutrophil chemotaxis

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25086

positive regulation of interleukin-6 production

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25086

Energy-sensing factors coactivator peroxisome proliferator-activated receptor γ coactivator 1-α (PGC-1α) and AMP-activated protein kinase control expression of inflammatory mediators in liver: induction of interleukin 1 receptor antagonist

response to starvation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25086

negative regulation of apoptotic process

1 reference

14 February 2019

Interleukin-1 beta induction of neuron apoptosis depends on p38 mitogen-activated protein kinase activity after spinal cord injury

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25086

positive regulation of I-kappaB kinase/NF-kappaB signaling

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25086

positive regulation of JUN kinase activity

1 reference

14 February 2019

Interleukin-1 receptor antagonist exerts agonist activity in the hippocampus independent of the interleukin-1 type I receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25086

negative regulation of membrane potential

1 reference

14 February 2019

Involvement of microglial P2X7 receptors and downstream signaling pathways in long-term potentiation of spinal nociceptive responses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25086

positive regulation of JNK cascade

IDA

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25086

response to interleukin-1

1 reference

14 February 2019

Regulation of brain interleukin-1 beta (IL-1 beta) system mRNAs in response to pathophysiological concentrations of IL-1 beta in the cerebrospinal fluid

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25086

response to interleukin-4

1 reference

14 February 2019

Suppression of monocyte function and differential regulation of IL-1 and IL-1ra by IL-4 contribute to resolution of experimental arthritis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25086

cellular response to lipopolysaccharide

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25086

cellular response to norepinephrine stimulus

1 reference

14 February 2019

Noradrenaline induces IL-1ra and IL-1 type II receptor expression in primary glial cells and protects against IL-1beta-induced neurotoxicity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25086

negative regulation of interleukin-1-mediated signaling pathway

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25086