(Q28563319)

STAT transcription factor, DNA-binding, N-terminal

1 reference

transcription factor STAT

1 reference

STAT transcription factor, coiled coil

1 reference

SH2 domain superfamily

1 reference

STAT transcription factor, N-terminal domain superfamily

1 reference

STAT transcription factor, protein interaction, protein family

1 reference

SH2 domain, protein family

1 reference

STAT transcription factor, DNA-binding domain, protein family

1 reference

STAT3, SH2 domain, protein family

1 reference

STAT transcription factor, all-alpha domain, protein family

1 reference

RNA polymerase II cis-regulatory region sequence-specific DNA binding

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

DNA-binding transcription factor activity, RNA polymerase II-specific

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

DNA-binding transcription activator activity, RNA polymerase II-specific

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

5 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

9 May 2019

Transcription factors Stat3 and Stat5b are present in rat liver nuclei late in an acute phase response and bind interleukin-6 response elements

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

DNA-binding transcription factor activity

4 references

9 May 2019

Transcription factors Stat3 and Stat5b are present in rat liver nuclei late in an acute phase response and bind interleukin-6 response elements

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

nuclear receptor activity

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

3 references

9 May 2019

ephrinB1 signals from the cell surface to the nucleus by recruitment of STAT3.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

9 May 2019

SH2B1β interacts with STAT3 and enhances fibroblast growth factor 1-induced gene expression during neuronal differentiation

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

9 May 2019

Signal regulatory protein alpha ligation induces macrophage nitric oxide production through JAK/STAT- and phosphatidylinositol 3-kinase/Rac1/NAPDH oxidase/H2O2-dependent pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

transcription factor binding

IPI

3 references

9 May 2019

Association of Stat3 with HSF1 plays a critical role in G-CSF-induced cardio-protection against ischemia/reperfusion injury

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

9 May 2019

In vivo GSH depletion induces c-myc expression by modulation of chromatin protein complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

protein phosphatase binding

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

CCR5 chemokine receptor binding

1 reference

9 May 2019

Chemokine receptor expression and in vivo signaling pathways in the joints of rats with adjuvant-induced arthritis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

glucocorticoid receptor binding

IPI

1 reference

9 May 2019

Association of the glucocorticoid receptor with STAT3, C/EBPbeta, and the hormone-responsive element within the rat haptoglobin gene promoter during the acute phase response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

identical protein binding

IPI

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

6 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

14 February 2019

Oxysterol and diabetes activate STAT3 and control endothelial expression of profilin-1 via OSBP1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

14 February 2019

Peptide YY attenuates STAT1 and STAT3 activation induced by TNF-alpha in acinar cell line AR42J

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

9 May 2019

Nuclear translocation of the transcription factor STAT5 in the rat brain after systemic leptin administration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

1 reference

9 May 2019

Change of cardiac mitochondrial STAT3 activity in rats with selenium deficiency and its relation with myocardial injury

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

mitochondrial inner membrane

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

1 reference

9 May 2019

Occurrence of a transcription factor, signal transducer and activators of transcription 3 (Stat3), in the postsynaptic density of the rat brain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

RNA polymerase II transcription regulator complex

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

Schaffer collateral - CA1 synapse

3 references

9 May 2019

The Jak/STAT pathway is involved in synaptic plasticity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

9 May 2019

The Jak/STAT pathway is involved in synaptic plasticity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

9 May 2019

The Jak/STAT pathway is involved in synaptic plasticity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

The Jak/STAT pathway is involved in synaptic plasticity

EXP

glutamatergic synapse

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

9 May 2019

The Jak/STAT pathway is involved in synaptic plasticity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

9 May 2019

The Jak/STAT pathway is involved in synaptic plasticity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

transcription regulator complex

EXP

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

7 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

9 May 2019

Peptide YY attenuates STAT1 and STAT3 activation induced by TNF-alpha in acinar cell line AR42J

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

9 May 2019

Oxysterol and diabetes activate STAT3 and control endothelial expression of profilin-1 via OSBP1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II

ISS

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

transcription by RNA polymerase II

ISS

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

1 reference

9 May 2019

Transcription factors Stat3 and Stat5b are present in rat liver nuclei late in an acute phase response and bind interleukin-6 response elements

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

receptor signaling pathway via JAK-STAT

1 reference

14 February 2019

Transcription factors Stat3 and Stat5b are present in rat liver nuclei late in an acute phase response and bind interleukin-6 response elements

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

cell population proliferation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

positive regulation of cell population proliferation

1 reference

9 May 2019

Multiple signaling pathways mediate ghrelin-induced proliferation of hippocampal neural stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

negative regulation of cell population proliferation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

response to organic substance

1 reference

9 May 2019

Protective effects of estradiol on ethanol-induced bone loss involve inhibition of reactive oxygen species generation in osteoblasts and downstream activation of the extracellular signal-regulated kinase/signal transducer and activator of [...]

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

negative regulation of autophagy

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

positive regulation of gene expression

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

negative regulation of hydrogen peroxide biosynthetic process

1 reference

9 May 2019

The STAT3 inhibitor stattic impairs cardiomyocyte mitochondrial function through increased reactive oxygen species formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

response to organic cyclic compound

1 reference

9 May 2019

Dual activation of STAT-3 and Akt is required during the trigger phase of ischaemic preconditioning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

stem cell population maintenance

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

positive regulation of cell migration

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

intracellular receptor signaling pathway

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

cellular response to hormone stimulus

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

1 reference

9 May 2019

Prevention of hypovolemic circulatory collapse by IL-6 activated Stat3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

miRNA-mediated gene silencing by inhibition of translation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

regulation of multicellular organism growth

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

mRNA transcription by RNA polymerase II

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

negative regulation of apoptotic process

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

response to peptide hormone

1 reference

14 February 2019

Signal transducer and activator of transcription 3-regulated sarcoendoplasmic reticulum Ca2+-ATPase 2 expression by prolactin and glucocorticoids is involved in the adaptation of insulin secretory response during the peripartum period

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

1 reference

9 May 2019

Protective effects of estradiol on ethanol-induced bone loss involve inhibition of reactive oxygen species generation in osteoblasts and downstream activation of the extracellular signal-regulated kinase/signal transducer and activator of [...]

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

positive regulation of angiogenesis

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

negative regulation of glycolytic process

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

positive regulation of transcription by RNA polymerase II

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

regulation of mitochondrial membrane permeability

1 reference

9 May 2019

The STAT3 inhibitor stattic impairs cardiomyocyte mitochondrial function through increased reactive oxygen species formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

modulation of chemical synaptic transmission

3 references

9 May 2019

The Jak/STAT pathway is involved in synaptic plasticity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

9 May 2019

The Jak/STAT pathway is involved in synaptic plasticity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

9 May 2019

The Jak/STAT pathway is involved in synaptic plasticity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

positive regulation of NF-kappaB transcription factor activity

EXP

1 reference

9 May 2019

TNF-α-sensitive brain pericytes activate microglia by releasing IL-6 through cooperation between IκB-NFκB and JAK-STAT3 pathways.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

growth hormone receptor signaling pathway

IGI

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

negative regulation of cell death

1 reference

9 May 2019

STAT3 deletion sensitizes cells to oxidative stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

cellular response to cytokine stimulus

1 reference

9 May 2019

JANEX-1, a JAK3 inhibitor, protects pancreatic islets from cytokine toxicity through downregulation of NF-kappaB activation and the JAK/STAT pathway

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

cellular response to organic cyclic compound

1 reference

9 May 2019

JANEX-1, a JAK3 inhibitor, protects pancreatic islets from cytokine toxicity through downregulation of NF-kappaB activation and the JAK/STAT pathway

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

postsynapse to nucleus signaling pathway

1 reference

9 May 2019

The Jak/STAT pathway is involved in synaptic plasticity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

negative regulation of neuron death

1 reference

9 May 2019

Survivin Is a transcriptional target of STAT3 critical to estradiol neuroprotection in global ischemia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

positive regulation of growth factor dependent skeletal muscle satellite cell proliferation

1 reference

9 May 2019

Interleukin-6-induced satellite cell proliferation is regulated by induction of the JAK2/STAT3 signalling pathway through cyclin D1 targeting

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

positive regulation of pri-miRNA transcription by RNA polymerase II

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

positive regulation of metalloendopeptidase activity

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

positive regulation of vascular endothelial cell proliferation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

positive regulation of gene silencing by miRNA

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

negative regulation of stem cell differentiation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

positive regulation of ATP biosynthetic process

1 reference

9 May 2019

The STAT3 inhibitor stattic impairs cardiomyocyte mitochondrial function through increased reactive oxygen species formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

negative regulation of neuron migration

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

cytokine-mediated signaling pathway

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

leptin-mediated signaling pathway

3 references

regulation of cell population proliferation

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

response to peptide hormone

2 references

9 May 2019

Signal transducer and activator of transcription 3-regulated sarcoendoplasmic reticulum Ca2+-ATPase 2 expression by prolactin and glucocorticoids is involved in the adaptation of insulin secretory response during the peripartum period

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52631

growth hormone receptor signaling pathway via JAK-STAT

3 references

STAT transcription factor, DNA-binding

1 reference

STAT transcription factor, all-alpha domain

1 reference

STAT transcription factor, protein interaction

1 reference

SH2 domain

1 reference

STAT3, SH2 domain

1 reference