(Q28570436)

31 January 2017

title

A role for DNA polymerase beta in mutagenic UV lesion bypass (English)

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31 January 2017

Laurence Servant

1

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31 January 2017

Christophe Cazaux

2

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31 January 2017

Anne Bieth

3

1 reference

31 January 2017

Shigenori Iwai

4

1 reference

31 January 2017

Fumio Hanaoka

5

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31 January 2017

Jean-Sébastien Hoffmann

6

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31 January 2017

language of work or name

English

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publication date

20 December 2002

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Journal of Biological Chemistry

31 January 2017

published in

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31 January 2017

volume

277

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31 January 2017

issue

51

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31 January 2017

page(s)

50046–50053

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Xeroderma pigmentosum variant (XP-V) correcting protein from HeLa cells has a thymine dimer bypass DNA polymerase activity

31 January 2017

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Human DINB1-encoded DNA polymerase kappa is a promiscuous extender of mispaired primer termini

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Response of human DNA polymerase iota to DNA lesions

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Abnormal, error-prone bypass of photoproducts by xeroderma pigmentosum variant cell extracts results in extreme strand bias for the kinds of mutations induced by UV light

21 January 2018

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hRAD30 mutations in the variant form of xeroderma pigmentosum

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The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase eta

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Molecular analysis of mutations in DNA polymerase eta in xeroderma pigmentosum-variant patients

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Overexpression of DNA polymerase beta in cell results in a mutator phenotype and a decreased sensitivity to anticancer drugs

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Differential gene expression in human cancer cells resistant to cisplatin

21 January 2018

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Nucleotide excision repair DNA synthesis by excess DNA polymerase beta: a potential source of genetic instability in cancer cells.

21 January 2018

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Melanoma and sun exposure: an overview of published studies

21 January 2018

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21 January 2018

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The Danish case-control study of cutaneous malignant melanoma. II. Importance of UV-light exposure

21 January 2018

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In vitro bypass replication of the cisplatin-d(GpG) lesion by calf thymus DNA polymerase beta and human immunodeficiency virus type I reverse transcriptase is highly mutagenic

21 January 2018

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21 January 2018

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Synthesis and characterization of a substrate for T4 endonuclease V containing a phosphorodithioate linkage at the thymine dimer site

21 January 2018

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Fork-like DNA templates support bypass replication of lesions that block DNA synthesis on single-stranded templates

21 January 2018

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Gel fidelity assay measuring nucleotide misinsertion, exonucleolytic proofreading, and lesion bypass efficiencies

21 January 2018

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Abasic translesion synthesis by DNA polymerase beta violates the "A-rule". Novel types of nucleotide incorporation by human DNA polymerase beta at an abasic lesion in different sequence contexts

21 January 2018

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Translesion replication by DNA polymerase beta is modulated by sequence context and stimulated by fork-like flap structures in DNA.

21 January 2018

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"Action-at-a-distance" mutagenesis. 8-oxo-7, 8-dihydro-2'-deoxyguanosine causes base substitution errors at neighboring template sites when copied by DNA polymerase beta.

21 January 2018

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Highly frequent frameshift DNA synthesis by human DNA polymerase mu

21 January 2018

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Involvement of DNA polymerase beta in DNA replication and mutagenic consequences

21 January 2018

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Differential replication of a single, UV-induced lesion in the leading or lagging strand by a human cell extract: fork uncoupling or gap formation

21 January 2018

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Replication of damaged DNA: molecular defect in xeroderma pigmentosum variant cells.

21 January 2018

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21 January 2018

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Distribution and repair of photolesions in DNA: genetic consequences and the role of sequence context

21 January 2018

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UV-induced mutagenesis in the endogenous hprt gene and in hprt cDNA genes integrated at different positions of the human genome

21 January 2018

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Evidence from mutation spectra that the UV hypermutability of xeroderma pigmentosum variant cells reflects abnormal, error-prone replication on a template containing photoproducts

21 January 2018

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Frequency of ultraviolet light-induced mutations is higher in xeroderma pigmentosum variant cells than in normal human cells

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M207101200

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017