(Q28572624)

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18524938%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

title

Dexamethasone increases expression and activity of multidrug resistance transporters at the rat blood-brain barrier (English)

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18524938%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

main subject

brain

0 references

multiple drug resistance

0 references

1 reference

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18524938%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

author name string

Charles Fraga

2

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18524938%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Jun Shen

4

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18524938%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Stacy Throm

5

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18524938%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Vishal S Narang

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18524938%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Clinton F Stewart

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18524938%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Christopher M Waters

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18524938%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

publication date

4 June 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18524938%20AND%20SRC:MED&resulttype=core&format=json

American Journal of Physiology - Cell Physiology

8 January 2020

published in

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18524938%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

volume

295

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18524938%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

issue

2

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18524938%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

page(s)

C440-50

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18524938%20AND%20SRC:MED&resulttype=core&format=json

Gene regulation by the glucocorticoid receptor: structure:function relationship

8 January 2020

cites work

1 reference

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Using real-time quantitative TaqMan RT-PCR to evaluate the role of dexamethasone in gene regulation of rat P-glycoproteins mdr1a/1b and cytochrome P450 3A1/2

19 March 2017

1 reference

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Functional expression of rat ABCG2 on the luminal side of brain capillaries and its enhancement by astrocyte-derived soluble factor(s)

19 March 2017

1 reference

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The nuclear pregnane X receptor: a key regulator of xenobiotic metabolism

19 March 2017

1 reference

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Dexamethasone induces the expression of metalloproteinase inhibitor TIMP-1 in the murine cerebral vascular endothelial cell line cEND.

19 March 2017

1 reference

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Human multidrug resistance ABCB and ABCG transporters: participation in a chemoimmunity defense system

29 September 2017

1 reference

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Ketoconazole and miconazole are antagonists of the human glucocorticoid receptor: consequences on the expression and function of the constitutive androstane receptor and the pregnane X receptor.

29 September 2017

1 reference

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Immunohistochemical detection of multidrug-resistant protein expression in retinoblastoma treated by primary enucleation

29 September 2017

1 reference

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The role of pregnane X receptor in 2-acetylaminofluorene-mediated induction of drug transport and -metabolizing enzymes in mice.

29 September 2017

1 reference

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Distribution and functional activity of P-glycoprotein and multidrug resistance-associated proteins in human brain microvascular endothelial cells in hippocampal sclerosis

29 September 2017

1 reference

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Use of P-glycoprotein and BCRP inhibitors to improve oral bioavailability and CNS penetration of anticancer drugs

29 September 2017

1 reference

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Evaluation of the immortalized human brain capillary endothelial cell line BB19 as a human cell culture model for the blood-brain barrier

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518425

Expression of the drug transporters MDR1/ABCB1, MRP1/ABCC1, MRP2/ABCC2, BCRP/ABCG2, and PXR in peripheral blood mononuclear cells and their relationship with the expression in intestine and liver

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518425

Differential regulation of the human MRP2 and MRP3 gene expression by glucocorticoids

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518425

Nuclear receptors and drug disposition gene regulation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518425

Blood-brain barrier active efflux transporters: ATP-binding cassette gene family

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518425

The management of brain edema in brain tumors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518425

Plasma pharmacokinetics and tissue distribution of the breast cancer resistance protein (BCRP/ABCG2) inhibitor fumitremorgin C in SCID mice bearing T8 tumors.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518425

Mrp4 confers resistance to topotecan and protects the brain from chemotherapy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518425

Induction of ABCC3 (MRP3) by pregnane X receptor activators

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518425

Distribution of STI-571 to the brain is limited by P-glycoprotein-mediated efflux

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518425

Dual effect of dexamethasone on CYP3A4 gene expression in human hepatocytes. Sequential role of glucocorticoid receptor and pregnane X receptor.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518425

Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518425

Promoter characterization and genomic organization of the human breast cancer resistance protein (ATP-binding cassette transporter G2) gene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518425

Dexamethasone regulation of P-glycoprotein activity in an immortalized rat brain endothelial cell line, GPNT.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518425

P-glycoprotein-mediated Hoechst 33342 transport out of the lipid bilayer.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518425

A comparison of primary cultures of rat cerebral microvascular endothelial cells to rat aortic endothelial cells

29 September 2017

1 reference

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29 September 2017

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1 reference

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Divergent regulation of the class II P-glycoprotein gene in primary cultures of hepatocytes versus H35 hepatoma by glucocorticoids.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518425

Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518425

Dexamethasone modulation of multidrug transporters in normal tissues.

3 June 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00491.2007

Regulation and induction of CYP3A11, CYP3A13 and CYP3A25 in C57BL/6J mouse liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00491.2007

Regulation by dexamethasone of P-glycoprotein expression in cultured rat hepatocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00491.2007

Irinotecan therapy in adults with recurrent or progressive malignant glioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00491.2007

Expression and regulation of breast cancer resistance protein and multidrug resistance associated protein 2 in BALB/c mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00491.2007

Ritonavir and dexamethasone induce expression of CYP3A and P-glycoprotein in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00491.2007

Glucocorticoid receptor enhancement of pregnane X receptor-mediated CYP2B6 regulation in primary human hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00491.2007

Pregnane X receptor up-regulation of P-glycoprotein expression and transport function at the blood-brain barrier

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518425

Up-regulation of multidrug resistance-associated protein 2 (MRP2) expression in rat hepatocytes by dexamethasone

27 November 2018

1 reference

12 December 2020

Use of dexamethasone in the treatment of cerebral edema resulting from brain tumors and brain surgery

1 reference

12 December 2020

The effect of Bcrp1 (Abcg2) on the in vivo pharmacokinetics and brain penetration of imatinib mesylate (Gleevec): implications for the use of breast cancer resistance protein and P-glycoprotein inhibitors to enable the brain penetration of imatinib

1 reference

12 December 2020

Dexamethasone induces pregnane X receptor and retinoid X receptor-alpha expression in human hepatocytes: synergistic increase of CYP3A4 induction by pregnane X receptor activators

1 reference

12 December 2020

10.1152/AJPCELL.00491.2007

Identifiers

DOI

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18524938%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18524938%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

2 references

31 January 2017