(Q28573156)

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Differential regulation of glutamate-cysteine ligase subunit expression and increased holoenzyme formation in response to cysteine deprivation

scientific journal article

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scholarly article

1 reference

31 January 2017

Differential regulation of glutamate-cysteine ligase subunit expression and increased holoenzyme formation in response to cysteine deprivation (English)

1 reference

31 January 2017

author name string

Jeong-In Lee

1

1 reference

31 January 2017

Joann Kang

2

1 reference

31 January 2017

Martha H. Stipanuk

3

1 reference

31 January 2017

language of work or name

0 references

publication date

1 January 2006

1 reference

31 January 2017

Biochemical Journal

1 reference

31 January 2017

393

1 reference

31 January 2017

Pt 1

1 reference

31 January 2017

181–190

1 reference

31 January 2017

Human glutamate cysteine ligase gene regulation through the electrophile response element

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383676

19 March 2017

Initial characterization of the glutamate-cysteine ligase modifier subunit Gclm(-/-) knockout mouse. Novel model system for a severely compromised oxidative stress response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383676

19 March 2017

Cysteine regulates expression of cysteine dioxygenase and gamma-glutamylcysteine synthetase in cultured rat hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383676

19 March 2017

Overexpression of the regulatory subunit of gamma-glutamylcysteine synthetase in HeLa cells increases gamma-glutamylcysteine synthetase activity and confers drug resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383676

19 March 2017

Identification of an important cysteine residue in human glutamate-cysteine ligase catalytic subunit by site-directed mutagenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383676

19 March 2017

Amino acid sequence and function of the light subunit of rat kidney gamma-glutamylcysteine synthetase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383676

19 March 2017

Cloning and sequencing of the cDNA for the light subunit of human liver gamma-glutamylcysteine synthetase and relative mRNA levels for heavy and light subunits in human normal tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383676

19 March 2017

Measurement of protein using bicinchoninic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383676

19 March 2017

Kinetic characteristics of native gamma-glutamylcysteine ligase in the aging housefly, Musca domestica L

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383676

29 September 2017

The modifier subunit of Drosophila glutamate-cysteine ligase regulates catalytic activity by covalent and noncovalent interactions and influences glutathione homeostasis in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383676

29 September 2017

Multi-faceted regulation of gamma-glutamylcysteine synthetase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383676

29 September 2017

Biologic and pharmacologic regulation of mammalian glutathione synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383676

29 September 2017

gamma-Glutamylcysteine synthetase. Further purification, "half of the sites" reactivity, subunits, and specificity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383676

29 September 2017

Differential regulation of gamma-glutamylcysteine synthetase heavy and light subunit gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383676

3 June 2018

Alteration of transcriptional and post-transcriptional expression of gamma-glutamylcysteine synthetase by diethyl maleate.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383676

3 June 2018

Regulation of cysteine dioxygenase and gamma-glutamylcysteine synthetase is associated with hepatic cysteine level

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383676

27 November 2018

Variable regulation of glutamate cysteine ligase subunit proteins affects glutathione biosynthesis in response to oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383676

27 November 2018

Effect of supplementation of n-3 polyunsaturated fatty acids on oxidative stress-induced DNA damage of rat hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383676

27 November 2018

Enzymes and metabolites of cysteine metabolism in nonhepatic tissues of rats show little response to changes in dietary protein or sulfur amino acid levels.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383676

27 November 2018

Drosophila melanogaster glutamate-cysteine ligase activity is regulated by a modifier subunit with a mechanism of action similar to that of the mammalian form

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383676

27 November 2018

gamma-glutamylcysteine synthetase: mRNA stabilization and independent subunit transcription by 4-hydroxy-2-nonenal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383676

27 November 2018

Posttranscriptional regulation of MRP/GS-X pump and gamma-glutamylcysteine synthetase expression by 1-(4-amino-2-methyl-5-pyrimidinyl) methyl-3-(2-chloroethyl)-3-nitrosourea and by cycloheximide in human glioma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383676

27 November 2018

Effects of monocrotaline, a pyrrolizidine alkaloid, on glutathione metabolism in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383676

27 November 2018

Comparison of sulfur amino acid utilization for GSH synthesis between HepG2 cells and cultured rat hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1383676

27 November 2018

Cysteine is the metabolic signal responsible for dietary regulation of hepatic cysteine dioxygenase and glutamate cysteine ligase in intact rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/16137247

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of gamma-glutamyl-cysteine synthetase by nonallosteric feedback inhibition by glutathione

1 reference

https://pubmed.ncbi.nlm.nih.gov/16137247

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversible dissociation of gamma-glutamylcysteine synthetase into two subunits

1 reference

https://pubmed.ncbi.nlm.nih.gov/16137247

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-performance liquid chromatography of thiols and disulfides: dinitrophenol derivatives

1 reference

https://pubmed.ncbi.nlm.nih.gov/16137247

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism of cysteine to taurine by rat hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16137247

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Catalytic and regulatory properties of the heavy subunit of rat kidney gamma-glutamylcysteine synthetase

1 reference

https://pubmed.ncbi.nlm.nih.gov/16137247

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutathione: an overview of biosynthesis and modulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16137247

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms involved in the regulation of key enzymes of cysteine metabolism in rat liver in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/16137247

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of nonsulfur and sulfur amino acids on the regulation of hepatic enzymes of cysteine metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/16137247

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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