(Q28576218)

English

Activation of opioid receptor like-1 receptor in the spinal cord produces sex-specific antinociception in the rat: estrogen attenuates antinociception in the female, whereas testosterone is required for the expression of antinociception in the male

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scholarly article

2 references

PubMed publication ID

31 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17167094%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

Activation of opioid receptor like-1 receptor in the spinal cord produces sex-specific antinociception in the rat: estrogen attenuates antinociception in the female, whereas testosterone is required for the expression of antinociception in the male (English)

2 references

PubMed publication ID

31 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17167094%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

0 references

negative regulation of sensory perception of pain

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

positive regulation of sensory perception of pain

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17167094%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

author name string

Jomo Claiborne

1

2 references

PubMed publication ID

31 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17167094%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

Sukhbir S Mokha

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17167094%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

language of work or name

0 references

publication date

1 December 2006

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17167094%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

Journal of Neuroscience

2 references

PubMed publication ID

31 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17167094%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

26

2 references

PubMed publication ID

31 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17167094%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

50

2 references

PubMed publication ID

31 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17167094%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

13048-13053

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17167094%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

Sex differences in pain

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct effect of intracerebroventricular and intrathecal injections of nociceptin/orphanin FQ in the rat formalin test.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nociceptin/orphanin FQ: role in nociceptive information processing

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estrogen Modulation of G-protein-coupled Receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estrogen-induced alterations of spinal cord enkephalin gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of the spinal opioid receptor like1 receptor, the NK-1 receptor, and cyclooxygenase-2 in maintaining postoperative pain in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nociceptin and the ORL-1 ligand [Phe1psi (CH2-NH)Gly2]nociceptin(1-13)NH2 exert anti-opioid effects in the Freund's adjuvant-induced arthritic rat model of chronic pain

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Opiate modulating properties of nociceptin/orphanin FQ.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacology of nociceptin and its receptor: a novel therapeutic target

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estrogen and endogenous opioids regulate CCK in reproductive circuits.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The molecular and behavioral pharmacology of the orphanin FQ/nociceptin peptide and receptor family

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Orphanin FQ produces gender-specific modulation of trigeminal nociception: behavioral and electrophysiological observations

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Contribution of GIRK2-mediated postsynaptic signaling to opiate and alpha 2-adrenergic analgesia and analgesic sex differences

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The melanocortin-1 receptor gene mediates female-specific mechanisms of analgesia in mice and humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sex-related differences in the distribution of opioid receptor-like 1 receptor mRNA and colocalization with estrogen receptor mRNA in neurons of the spinal trigeminal nucleus caudalis in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estrogen Modulates the Visceromotor Reflex and Responses of Spinal Dorsal Horn Neurons to Colorectal Stimulation in the Rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Utilizing functional genomics to identify new pain treatments : the example of nociceptin

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sex differences in pain and analgesia: the role of gonadal hormones

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sex differences in opioid analgesia: clinical and experimental findings.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estrogen modulation of hypothalamic neurons: activation of multiple signaling pathways and gene expression changes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulatory effects of estrogen and progesterone on colorectal hyperalgesia in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of the antinociceptive response to morphine and morphine-like compounds in male and female Sprague-Dawley rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Site-specific estrogen and progestin regulation of orphanin FQ/nociceptin and nociceptin opioid receptor mRNA expression in the female rat limbic hypothalamic system.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of alpha2-adrenoceptors in the trigeminal region produces sex-specific modulation of nociception in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nociceptive action of excitatory amino acids in the mouse: effects of spinally administered opioids, phencyclidine and sigma agonists.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Desensitization of brain opiate receptor mechanisms by gonadal steroid treatments that stimulate luteinizing hormone secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma concentration of LH, FSH, prolactin, progesterone and estradiol-17beta throughout the 4-day estrous cycle of the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Orphanin FQ: a neuropeptide that activates an opioidlike G protein-coupled receptor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Temporal regulation by estrogen of beta-preprotachykinin mRNA expression in the rat ventromedial nucleus of the hypothalamus

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

17 beta-estradiol and progesterone positively modulate spinal cord dynorphin: relevance to the analgesia of pregnancy

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular cloning, tissue distribution and chromosomal localization of a novel member of the opioid receptor gene family

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular cloning and tissue distribution of a putative member of the rat opioid receptor gene family that is not a mu, delta or kappa opioid receptor type

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ORL1, a novel member of the opioid receptor family. Cloning, functional expression and localization

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure, tissue distribution, and chromosomal localization of the prepronociceptin gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitory action of nociceptin on spinal dorsal horn neurones of the rat, in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Naloxone sensitive orphanin FQ-induced analgesia in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kappa-opioids produce significantly greater analgesia in women than in men.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nociceptin or antinociceptin: potent spinal antinociceptive effect of orphanin FQ/nociceptin in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Orphanin FQ acts as a supraspinal, but not a spinal, anti-opioid peptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Orphanin FQ is a functional anti-opioid peptide.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Colocalization of Oestrogen Receptor lmmunoreactivity and Preproenkephalin mRNA Expression to Neurons in the Superficial Laminae of the Spinal and Medullary Dorsal Horn of Rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spinal analgesic activity of orphanin FQ/nociceptin and its fragments

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of excitatory synaptic transmission by nociceptin in superficial dorsal horn neurones of the neonatal rat spinal cord

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spinally delivered nociceptin/orphanin FQ reduces flinching behaviour in the rat formalin test

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The orphan opioid receptor and its endogenous ligand--nociceptin/orphanin FQ

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analgesic effect of intrathecally administered nociceptin, an opioid receptor-like1 receptor agonist, in the rat formalin test

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nociceptin-like immunoreactivity in the rat dorsal horn and inhibition of substantia gelatinosa neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of intrathecally administered nociceptin, an opioid receptor-like1 receptor agonist, and N-methyl-D-aspartate receptor antagonists on the thermal hyperalgesia induced by partial sciatic nerve injury in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estrogen modulation of opioid and cholecystokinin systems in the limbic-hypothalamic circuit

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative distribution of estrogen receptor-alpha and -beta mRNA in the rat central nervous system.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Circuitry underlying antiopioid actions of orphanin FQ in the rostral ventromedial medulla.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Orphanin FQ/nociceptin in the ventromedial nucleus facilitates lordosis in female rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nociceptin/orphanin FQ and the opioid receptor-like ORL1 receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-hyperalgesic and anti-allodynic effects of intrathecal nociceptin/orphanin FQ in rats after spinal cord injury, peripheral nerve injury and inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Naltrexone, but not atropine or yohimbine, antagonizes suppression of formalin-induced spinal sensitization by intrathecal nociceptin

1 reference

https://pubmed.ncbi.nlm.nih.gov/17167094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.4783-06.2006

2 references

PubMed publication ID

31 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17167094%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

release_d6dqvdtenrbqhmjft3s2ijzpme

1 reference

https://api.fatcat.wiki/v0/release/d6dqvdtenrbqhmjft3s2ijzpme

24 November 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17167094%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

PubMed publication ID

2 references

PubMed publication ID

31 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17167094%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

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