(Q28580371)

31 January 2017

title

Activation of the prolyl-hydroxylase oxygen-sensing signal cascade leads to AMPK activation in cardiomyocytes (English)

1 reference

regulation of CAMKK-AMPK signaling cascade

31 January 2017

main subject

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:1905289

negative regulation of CAMKK-AMPK signaling cascade

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:1905290

positive regulation of CAMKK-AMPK signaling cascade

1 reference

Gene Ontology release 2020-05-02

1 reference

Hong Yan

1

1 reference

31 January 2017

Dong-Xia Zhang

2

1 reference

31 January 2017

Xiaohua Shi

3

1 reference

31 January 2017

Qiong Zhang

4

1 reference

31 January 2017

Yue-Sheng Huang

5

1 reference

31 January 2017

publication date

1 September 2012

1 reference

Journal of Cellular and Molecular Medicine

31 January 2017

published in

1 reference

31 January 2017

volume

16

1 reference

31 January 2017

issue

9

1 reference

31 January 2017

page(s)

2049–2059

1 reference

LKB1, an upstream AMPK kinase, regulates glucose and lipid metabolism in cultured liver and muscle cells

31 January 2017

cites work

1 reference

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Studies on the activity of the hypoxia-inducible-factor hydroxylases using an oxygen consumption assay

17 March 2017

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Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3822975

Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor

17 March 2017

1 reference

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The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress

17 March 2017

1 reference

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Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3822975

HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia

17 March 2017

1 reference

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Characterization of the human prolyl 4-hydroxylases that modify the hypoxia-inducible factor

17 March 2017

1 reference

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von Hippel-Lindau protein binds hyperphosphorylated large subunit of RNA polymerase II through a proline hydroxylation motif and targets it for ubiquitination

17 March 2017

1 reference

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A conserved family of prolyl-4-hydroxylases that modify HIF

17 March 2017

1 reference

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HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

17 March 2017

1 reference

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Hypoxia and hypoxia/reoxygenation activate p65PAK, p38 mitogen-activated protein kinase (MAPK), and stress-activated protein kinase (SAPK) in cultured rat cardiac myocytes

17 March 2017

1 reference

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AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism

17 March 2017

1 reference

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A novel mode of action of YC-1 in HIF inhibition: stimulation of FIH-dependent p300 dissociation from HIF-1{alpha}.

7 April 2017

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Prolyl hydroxylase-1 negatively regulates IkappaB kinase-beta, giving insight into hypoxia-induced NFkappaB activity

29 September 2017

1 reference

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Concordant regulation of gene expression by hypoxia and 2-oxoglutarate-dependent dioxygenase inhibition: the role of HIF-1alpha, HIF-2alpha, and other pathways

29 September 2017

1 reference

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Chutes and Ladders: the search for protein kinases that act on AMPK.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3822975

Deficiency of LKB1 in heart prevents ischemia-mediated activation of AMPKalpha2 but not AMPKalpha1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3822975

Ca2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3822975

The Ca2+/calmodulin-dependent protein kinase kinases are AMP-activated protein kinase kinases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3822975

AMP-activated protein kinase: the guardian of cardiac energy status.

29 September 2017

1 reference

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STO-609, a specific inhibitor of the Ca(2+)/calmodulin-dependent protein kinase kinase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3822975

Glucose uptake and glycolysis reduce hypoxia-induced apoptosis in cultured neonatal rat cardiac myocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3822975

Tissue distribution of the AMP-activated protein kinase, and lack of activation by cyclic-AMP-dependent protein kinase, studied using a specific and sensitive peptide assay

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3822975

Activation of the prolyl hydroxylase oxygen-sensor results in induction of GLUT1, heme oxygenase-1, and nitric-oxide synthase proteins and confers protection from metabolic inhibition to cardiomyocytes

3 June 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2011.01500.X

The prolyl hydroxylase oxygen-sensing pathway is cytoprotective and allows maintenance of mitochondrial membrane potential during metabolic inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2011.01500.X

Adenosine 5'-monophosphate-activated protein kinase and p38 mitogen-activated protein kinase participate in the stimulation of glucose uptake by dinitrophenol in adult cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2011.01500.X

Hypoxia inducible factor-1 activation by prolyl 4-hydroxylase-2 gene silencing attenuates myocardial ischemia reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2011.01500.X

Dual mechanisms regulating AMPK kinase action in the ischemic heart.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3822975

Prolyl hydroxylase inhibitor treatment confers whole-animal hypoxia tolerance

27 November 2018

1 reference

12 December 2020

Myocardial ischemia differentially regulates LKB1 and an alternate 5'-AMP-activated protein kinase kinase

1 reference

12 December 2020

Prolyl hydroxylase inhibitors delay neuronal cell death caused by trophic factor deprivation

1 reference

12 December 2020

Mechanism of acetylcholine-induced calcium signaling during neuronal differentiation of P19 embryonal carcinoma cells in vitro

1 reference

12 December 2020

Rapid determination of creatine, phosphocreatine, purine bases and nucleotides (ATP, ADP, AMP, GTP, GDP) in heart biopsies by gradient ion-pair reversed-phase liquid chromatography

1 reference

12 December 2020

10.1111/J.1582-4934.2011.01500.X

Identifiers

DOI

1 reference

31 January 2017

0 references

1 reference