(Q28581484)

31 January 2017

title

Insulin enhances post-translational processing of nascent SREBP-1c by promoting its phosphorylation and association with COPII vesicles (English)

1 reference

31 January 2017

0 references

1 reference

Chandrahasa R. Yellaturu

1

1 reference

31 January 2017

Xiong Deng

2

1 reference

31 January 2017

Lauren M. Cagen

3

1 reference

31 January 2017

Henry G. Wilcox

4

1 reference

31 January 2017

Charles M. Mansbach

5

1 reference

31 January 2017

Shadab A. Siddiqi

6

1 reference

31 January 2017

Edwards A. Park

7

1 reference

31 January 2017

Rajendra Raghow

8

1 reference

31 January 2017

Marshall B. Elam

9

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31 January 2017

language of work or name

English

0 references

publication date

20 March 2009

1 reference

Journal of Biological Chemistry

31 January 2017

published in

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31 January 2017

volume

284

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31 January 2017

issue

12

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31 January 2017

page(s)

7518–7532

1 reference

describes a project that uses

31 January 2017

ImageJ

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2658047/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Distinct roles of insulin and liver X receptor in the induction and cleavage of sterol regulatory element-binding protein-1c

17 March 2017

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SREBP transcription factors: master regulators of lipid homeostasis

17 March 2017

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Cholesterol-induced conformational change in SCAP enhanced by Insig proteins and mimicked by cationic amphiphiles

17 March 2017

1 reference

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Liver-specific mRNA for Insig-2 down-regulated by insulin: implications for fatty acid synthesis

17 March 2017

1 reference

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Insig-2, a second endoplasmic reticulum protein that binds SCAP and blocks export of sterol regulatory element-binding proteins

17 March 2017

1 reference

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MAP kinases Erk1/2 phosphorylate sterol regulatory element-binding protein (SREBP)-1a at serine 117 in vitro

17 March 2017

1 reference

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A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood

17 March 2017

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ADD1/SREBP-1c is required in the activation of hepatic lipogenic gene expression by glucose

17 March 2017

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The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor

17 March 2017

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Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells

17 March 2017

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The insulin signaling system

17 March 2017

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Structure of the human gene encoding sterol regulatory element binding protein-1 (SREBF1) and localization of SREBF1 and SREBF2 to chromosomes 17p11.2 and 22q13

17 March 2017

1 reference

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Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

17 March 2017

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SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

17 March 2017

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Critical nodes in signalling pathways: insights into insulin action

7 April 2017

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Protein sensors for membrane sterols

7 April 2017

1 reference

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The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658047

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

7 April 2017

1 reference

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SREBPs: the crossroads of physiological and pathological lipid homeostasis

7 April 2017

1 reference

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Regulation of sterol synthesis in eukaryotes.

29 September 2017

1 reference

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Expression of the rat sterol regulatory element-binding protein-1c gene in response to insulin is mediated by increased transactivating capacity of specificity protein 1 (Sp1).

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658047

SREBPs: sterol-regulated transcription factors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658047

Sterol regulatory element-binding protein 1 is negatively modulated by PKA phosphorylation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658047

The phosphoinositol-3-kinase-protein kinase B/Akt pathway is critical for Pseudomonas aeruginosa strain PAK internalization

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658047

Dexamethasone induces apoptosis in proliferative chondrocytes through activation of caspases and suppression of the Akt-phosphatidylinositol 3'-kinase signaling pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658047

Molecular regulation of SREBP function: the Insig-SCAP connection and isoform-specific modulation of lipid synthesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658047

New perspectives in the regulation of hepatic glycolytic and lipogenic genes by insulin and glucose: a role for the transcription factor sterol regulatory element binding protein-1c

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658047

Glucose and insulin function through two distinct transcription factors to stimulate expression of lipogenic enzyme genes in liver.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658047

Regulation of gene expression by SREBP and SCAP.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658047

Insulin selectively increases SREBP-1c mRNA in the livers of rats with streptozotocin-induced diabetes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658047

Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658047

Increased levels of nuclear SREBP-1c associated with fatty livers in two mouse models of diabetes mellitus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658047

Regulation of sterol regulatory element binding proteins in livers of fasted and refed mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658047

Cargo selection by the COPII budding machinery during export from the ER

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658047

Nutritional and insulin regulation of fatty acid synthetase and leptin gene expression through ADD1/SREBP1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658047

COPII vesicles derived from mammalian endoplasmic reticulum microsomes recruit COPI

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658047

Insulin promotes the biosynthesis and secretion of apolipoprotein B-48 by altering apolipoprotein B mRNA editing

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658047

Independent regulation of sterol regulatory element-binding proteins 1 and 2 in hamster liver

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658047

Insulin receptor signaling. Activation of multiple serine kinases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658047

Insulin activates the rat sterol-regulatory-element-binding protein 1c (SREBP-1c) promoter through the combinatorial actions of SREBP, LXR, Sp-1 and NF-Y cis-acting elements

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658047

Insulin effects on sterol regulatory-element-binding protein-1c (SREBP-1c) transcriptional activity in rat hepatocytes.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658047

Regulation of protein phosphatase 1 and 2A activities by insulin during myogenesis in rat skeletal muscle cells in culture.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658047

COPII-cargo interactions direct protein sorting into ER-derived transport vesicles

3 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805746200

Control of lipid metabolism by phosphorylation-dependent degradation of the SREBP family of transcription factors by SCF(Fbw7).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805746200

Role of the insulin receptor substrate 1 and phosphatidylinositol 3-kinase signaling pathway in insulin-induced expression of sterol regulatory element binding protein 1c and glucokinase genes in rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805746200

Regulation of sterol regulatory-element binding protein 1 gene expression in liver: role of insulin and protein kinase B/cAkt

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805746200

Hepatic Akt activation induces marked hypoglycemia, hepatomegaly, and hypertriglyceridemia with sterol regulatory element binding protein involvement

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805746200

Analysis of the role of protein kinase B (cAKT) in insulin-dependent induction of glucokinase and sterol regulatory element-binding protein 1 (SREBP1) mRNAs in hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805746200

Posttranslational processing of SREBP-1 in rat hepatocytes is regulated by insulin and cAMP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805746200

Divergent regulation of hepatic glucose and lipid metabolism by phosphoinositide 3-kinase via Akt and PKCλ/ζ

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805746200

Increased hepatic VLDL secretion, lipogenesis, and SREBP-1 expression in the corpulent JCR:LA-cp rat.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658047

Kinase signaling initiates coat complex II (COPII) recruitment and export from the mammalian endoplasmic reticulum

27 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/19158095

12 December 2020

inferred from PubMed ID database lookup

Sequential activation of MAP kinase activator, MAP kinases, and S6 peptide kinase in intact rat liver following insulin injection

1 reference

https://pubmed.ncbi.nlm.nih.gov/19158095

12 December 2020

inferred from PubMed ID database lookup

Signalling pathways involved in the stimulation of glycogen synthesis by insulin in rat hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19158095

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1074/JBC.M805746200

1 reference

release_c3ueyprgyrhydcfcavylcgmof4

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/c3ueyprgyrhydcfcavylcgmof4

24 November 2022

mapped directly with Wikidata item

1 reference

1 reference

1 reference