(Q28581518)

English

Neuroprotective effects of hydroxysafflor yellow A against excitotoxic neuronal death partially through down-regulation of NR2B-containing NMDA receptors

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scholarly article

1 reference

31 January 2017

Neuroprotective effects of hydroxysafflor yellow A against excitotoxic neuronal death partially through down-regulation of NR2B-containing NMDA receptors (English)

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31 January 2017

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inferred from title

author name string

Q. Yang

1

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31 January 2017

Z.-F. Yang

2

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31 January 2017

S.-B. Liu

3

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31 January 2017

X.-N. Zhang

4

1 reference

31 January 2017

Y. Hou

5

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31 January 2017

X.-Q. Li

6

1 reference

31 January 2017

Y.-M. Wu

7

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31 January 2017

A.-D. Wen

8

1 reference

31 January 2017

Ming-Gao Zhao

9

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31 January 2017

publication date

1 September 2010

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31 January 2017

Neurochemical Research

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31 January 2017

35

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31 January 2017

9

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31 January 2017

1353–1360

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31 January 2017

https://scigraph.springernature.com/pub.10.1007/s11064-010-0191-6

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Glutamate mediates cell death and increases the Bax to Bcl-2 ratio in a differentiated neuronal cell line

1 reference

https://pubmed.ncbi.nlm.nih.gov/20526740

12 December 2020

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inferred from PubMed ID database lookup

Coupling diverse routes of calcium entry to mitochondrial dysfunction and glutamate excitotoxicity

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https://pubmed.ncbi.nlm.nih.gov/20526740

12 December 2020

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inferred from PubMed ID database lookup

Hydroxysafflor yellow A enhances survival of vascular endothelial cells under hypoxia via upregulation of the HIF-1 alpha-VEGF pathway and regulation of Bcl-2/Bax

1 reference

https://pubmed.ncbi.nlm.nih.gov/20526740

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Developmental changes in NMDA neurotoxicity reflect developmental changes in subunit composition of NMDA receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20526740

12 December 2020

based on heuristic

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Medicines from nature: are natural products still relevant to drug discovery?

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https://pubmed.ncbi.nlm.nih.gov/20526740

12 December 2020

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Superoxide production in rat hippocampal neurons: selective imaging with hydroethidine

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https://pubmed.ncbi.nlm.nih.gov/20526740

12 December 2020

based on heuristic

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Distinct roles of synaptic and extrasynaptic NMDA receptors in excitotoxicity

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https://pubmed.ncbi.nlm.nih.gov/20526740

12 December 2020

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Safflor yellow B suppresses pheochromocytoma cell (PC12) injury induced by oxidative stress via antioxidant system and Bcl-2 /Bax pathway.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20526740

12 December 2020

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Hydroxysafflor yellow A protects rat brains against ischemia-reperfusion injury by antioxidant action

1 reference

https://pubmed.ncbi.nlm.nih.gov/20526740

12 December 2020

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Effect of Hydroxysafflor yellow A on human umbilical vein endothelial cells under hypoxia

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https://pubmed.ncbi.nlm.nih.gov/20526740

12 December 2020

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Neuroprotective effects of hydroxysafflor yellow A: in vivo and in vitro studies

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https://pubmed.ncbi.nlm.nih.gov/20526740

12 December 2020

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NMDA-receptor-dependent synaptic plasticity: multiple forms and mechanisms

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https://pubmed.ncbi.nlm.nih.gov/20526740

12 December 2020

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The role of superoxide and nuclear factor-kappaB signaling in N-methyl-D-aspartate-induced necrosis and apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20526740

12 December 2020

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Ionized intracellular calcium concentration predicts excitotoxic neuronal death: observations with low-affinity fluorescent calcium indicators

1 reference

https://pubmed.ncbi.nlm.nih.gov/20526740

12 December 2020

based on heuristic

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Flow cytometry as a method for studying effects of stressors on primary rat neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/20526740

12 December 2020

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Mitochondria and the Bcl-2 family proteins in apoptosis signaling pathways.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20526740

12 December 2020

based on heuristic

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Expression mechanisms underlying NMDA receptor-dependent long-term potentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20526740

12 December 2020

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The N-methyl-D-aspartate receptor subunit NR2B: localization, functional properties, regulation, and clinical implications.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20526740

12 December 2020

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Neuroprotective effects of safflor yellow B on brain ischemic injury.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20526740

12 December 2020

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Optimized survival of hippocampal neurons in B27-supplemented Neurobasal, a new serum-free medium combination

1 reference

https://pubmed.ncbi.nlm.nih.gov/20526740

12 December 2020

based on heuristic

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A synaptic model of memory: long-term potentiation in the hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/20526740

12 December 2020

based on heuristic

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The Yin and Yang of NMDA receptor signalling

1 reference

https://pubmed.ncbi.nlm.nih.gov/20526740

12 December 2020

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The protective effects of Achyranthes bidentata polypeptides against NMDA-induced cell apoptosis in cultured hippocampal neurons through differential modulation of NR2A- and NR2B-containing NMDA receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/20526740

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Herbal medicine in stroke: does it have a future?

1 reference

https://pubmed.ncbi.nlm.nih.gov/20526740

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Developmental and regional expression in the rat brain and functional properties of four NMDA receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/20526740

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mechanisms of calcium-dependent neurodegeneration in excitotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20526740

12 December 2020

based on heuristic

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The NMDA receptor is coupled to the ERK pathway by a direct interaction between NR2B and RasGRF1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20526740

12 December 2020

based on heuristic

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Hypoxic/ischemic conditions induce expression of the putative pro-death gene Clca1 via activation of extrasynaptic N-methyl-D-aspartate receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/20526740

12 December 2020

based on heuristic

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Apoptosis and the receptor specificity of its mechanisms during the neurotoxic action of glutamate

1 reference

https://pubmed.ncbi.nlm.nih.gov/20526740

12 December 2020

based on heuristic

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Hydroxysafflor yellow A protects neuron against hypoxia injury and suppresses inflammatory responses following focal ischemia reperfusion in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/20526740

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

N-methyl-D-aspartate receptor antagonist activity in traditional Chinese stroke medicines

1 reference

https://pubmed.ncbi.nlm.nih.gov/20526740

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Excitotoxicity in vitro by NR2A- and NR2B-containing NMDA receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20526740

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NADPH oxidase is the primary source of superoxide induced by NMDA receptor activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20526740

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Possible protection by notoginsenoside R1 against glutamate neurotoxicity mediated by N-methyl-D-aspartate receptors composed of an NR1/NR2B subunit assembly

1 reference

https://pubmed.ncbi.nlm.nih.gov/20526740

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial dysfunction is a primary event in glutamate neurotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20526740

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FMRP acts as a key messenger for dopamine modulation in the forebrain

1 reference

https://pubmed.ncbi.nlm.nih.gov/20526740

12 December 2020

based on heuristic

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NMDA receptor subunits have differential roles in mediating excitotoxic neuronal death both in vitro and in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20526740

12 December 2020

based on heuristic

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Down-regulation of NR2B receptors partially contributes to analgesic effects of Gentiopicroside in persistent inflammatory pain

1 reference

https://pubmed.ncbi.nlm.nih.gov/20526740

12 December 2020

based on heuristic

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Activation of a caspase 3-related cysteine protease is required for glutamate-mediated apoptosis of cultured cerebellar granule neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/20526740

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of activated caspase-3-like proteases in N-methyl-D-aspartate-induced apoptosis in cerebrocortical neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/20526740

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NMDA and glutamate evoke excitotoxicity at distinct cellular locations in rat cortical neurons in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/20526740

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alkaloid fraction of Uncaria rhynchophylla protects against N-methyl-D-aspartate-induced apoptosis in rat hippocampal slices

1 reference

https://pubmed.ncbi.nlm.nih.gov/20526740

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Salidroside attenuates glutamate-induced apoptotic cell death in primary cultured hippocampal neurons of rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/20526740

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/20526740

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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