(Q28584355)

English

HCN1 and HCN2 proteins are expressed in cochlear hair cells: HCN1 can form a ternary complex with protocadherin 15 CD3 and F-actin-binding filamin A or can interact with HCN2

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scholarly article

1 reference

31 January 2017

HCN1 and HCN2 proteins are expressed in cochlear hair cells: HCN1 can form a ternary complex with protocadherin 15 CD3 and F-actin-binding filamin A or can interact with HCN2 (English)

1 reference

31 January 2017

author name string

Neeliyath A. Ramakrishnan

1

1 reference

31 January 2017

Marian J. Drescher

2

1 reference

31 January 2017

Khalid M. Khan

3

1 reference

31 January 2017

James S. Hatfield

4

1 reference

31 January 2017

Dennis G. Drescher

5

1 reference

31 January 2017

language of work or name

0 references

publication date

2 November 2012

1 reference

31 January 2017

Journal of Biological Chemistry

1 reference

31 January 2017

287

1 reference

31 January 2017

45

1 reference

31 January 2017

37628–37646

1 reference

31 January 2017

Mechanotransduction in mouse inner ear hair cells requires transmembrane channel-like genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488041

17 March 2017

Myosin VIIa and sans localization at stereocilia upper tip-link density implicates these Usher syndrome proteins in mechanotransduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488041

17 March 2017

Regulation of PCDH15 function in mechanosensory hair cells by alternative splicing of the cytoplasmic domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488041

17 March 2017

HCN channels are not required for mechanotransduction in sensory hair cells of the mouse inner ear.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488041

17 March 2017

Calcium-dependent binding of HCN1 channel protein to hair cell stereociliary tip link protein protocadherin 15 CD3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488041

17 March 2017

The chloride intracellular channel protein CLIC5 is expressed at high levels in hair cell stereocilia and is essential for normal inner ear function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488041

17 March 2017

Hypoosmotic cell swelling as a novel mechanism for modulation of cloned HCN2 channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488041

17 March 2017

TRPA1 is a candidate for the mechanosensitive transduction channel of vertebrate hair cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488041

17 March 2017

PCDH15 is expressed in the neurosensory epithelium of the eye and ear and mutant alleles are responsible for both USH1F and DFNB23

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488041

17 March 2017

Role of subunit heteromerization and N-linked glycosylation in the formation of functional hyperpolarization-activated cyclic nucleotide-gated channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488041

17 March 2017

Expression of subunits for the cAMP-sensitive 'olfactory' cyclic nucleotide-gated ion channel in the cochlea: implications for signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488041

17 March 2017

Molecular characterization of a slowly gating human hyperpolarization-activated channel predominantly expressed in thalamus, heart, and testis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488041

17 March 2017

Mechanical strain in actin networks regulates FilGAP and integrin binding to filamin A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488041

29 September 2017

TRPA1-mediated accumulation of aminoglycosides in mouse cochlear outer hair cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488041

29 September 2017

Polycystin-1 is required for stereocilia structure but not for mechanotransduction in inner ear hair cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488041

29 September 2017

The magnitudes of hyperpolarization-activated and low-voltage-activated potassium currents co-vary in neurons of the ventral cochlear nucleus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488041

29 September 2017

Mechanism of spontaneous activity in afferent neurons of the zebrafish lateral-line organ.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488041

29 September 2017

An adenylyl cyclase signaling pathway predicts direct dopaminergic input to vestibular hair cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488041

29 September 2017

Dendritic HCN channels shape excitatory postsynaptic potentials at the inner hair cell afferent synapse in the mammalian cochlea

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488041

29 September 2017

Homeostatic regulation of synaptic excitability: tonic GABA(A) receptor currents replace I(h) in cortical pyramidal neurons of HCN1 knock-out mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488041

29 September 2017

Interaction between CFTR and prestin (SLC26A5)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488041

29 September 2017

Hyperpolarization-activated cation channels: from genes to function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488041

29 September 2017

Proteolytic processing of HCN2 and co-assembly with HCN4 in the generation of cardiac pacemaker channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488041

29 September 2017

P2X antagonists inhibit styryl dye entry into hair cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488041

29 September 2017

Short interfering RNA against transient receptor potential vanilloid 1 attenuates cisplatin-induced hearing loss in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488041

29 September 2017

Surface plasmon resonance (SPR) analysis of binding interactions of proteins in inner-ear sensory epithelia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488041

29 September 2017

TRPV4 enhances the cellular uptake of aminoglycoside antibiotics.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488041

29 September 2017

Cadherin 23 and protocadherin 15 interact to form tip-link filaments in sensory hair cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488041

29 September 2017

Modulation of cyclic nucleotide-regulated HCN channels by PIP(2) and receptors coupled to phospholipase C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488041

29 September 2017

Steady-state adaptation of mechanotransduction modulates the resting potential of auditory hair cells, providing an assay for endolymph [Ca2+].

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488041

29 September 2017

The enhancement of HCN channel instantaneous current facilitated by slow deactivation is regulated by intracellular chloride concentration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488041

29 September 2017

Distinct populations of HCN pacemaker channels produce voltage-dependent and voltage-independent currents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488041

29 September 2017

Interaction of the pacemaker channel HCN1 with filamin A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488041

29 September 2017

Structural elements of instantaneous and slow gating in hyperpolarization-activated cyclic nucleotide-gated channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488041

29 September 2017

KCNE2 modulates current amplitudes and activation kinetics of HCN4: influence of KCNE family members on HCN4 currents.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488041

29 September 2017

Ionic currents expressed in a cell line derived from the organ of Corti of the Immortomouse.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488041

29 September 2017

Molecular characterization of the hyperpolarization-activated cation channel in rabbit heart sinoatrial node

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488041

29 September 2017

A family of hyperpolarization-activated mammalian cation channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488041

29 September 2017

Molecular identification of a hyperpolarization-activated channel in sea urchin sperm

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488041

29 September 2017

Low-conductance HCN1 ion channels augment the frequency response of rod and cone photoreceptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488041

3 June 2018

Dual stretch responses of mHCN2 pacemaker channels: accelerated activation, accelerated deactivation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488041

3 June 2018

Hyperpolarization-activated, cyclic AMP-gated, HCN1-like cation channel: the primary, full-length HCN isoform expressed in a saccular hair-cell layer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488041

3 June 2018

Pacemaker channels produce an instantaneous current.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488041

3 June 2018

A cyclic-AMP-gated conductance in cochlear hair cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488041

3 June 2018

Duplicated genes with split functions: independent roles of protocadherin15 orthologues in zebrafish hearing and vision

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.375832

21 January 2018

Selective expression of serotonin receptor transcripts in the mammalian cochlea and its subdivisions.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.375832

21 January 2018

The hyperpolarization-activated HCN1 channel is important for motor learning and neuronal integration by cerebellar Purkinje cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.375832

21 January 2018

Light responses in the mouse retina are prolonged upon targeted deletion of the HCN1 channel gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.375832

21 January 2018

Non-equilibrium behavior of HCN channels: insights into the role of HCN channels in native and engineered pacemakers.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.375832

21 January 2018

Separable gating mechanisms in a Mammalian pacemaker channel.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.375832

21 January 2018

Hair cells require phosphatidylinositol 4,5-bisphosphate for mechanical transduction and adaptation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.375832

21 January 2018

Pairwise coupling of hair cell transducer channels links auditory sensitivity and dynamic range.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.375832

21 January 2018

TRPML3 mutations cause impaired mechano-electrical transduction and depolarization by an inward-rectifier cation current in auditory hair cells of varitint-waddler mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.375832

21 January 2018

Developmental expression of the potassium current IK,n contributes to maturation of mouse outer hair cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.375832

21 January 2018

Tmc1 is necessary for normal functional maturation and survival of inner and outer hair cells in the mouse cochlea.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.375832

21 January 2018

CNGA3 is expressed in inner ear hair cells and binds to an intracellular C-terminus domain of EMILIN1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.375832

21 January 2018

HCN2 Ion Channels Play a Central Role in Inflammatory and Neuropathic Pain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.375832

21 January 2018

Putative immunolocalization of the mechanoelectrical transduction channels in mammalian cochlear hair cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22948144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fluorescence imaging of extracellular purinergic receptor sites and putative ecto-ATPase sites on isolated cochlear hair cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22948144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inwardly rectifying currents of saccular hair cells from the leopard frog

1 reference

https://pubmed.ncbi.nlm.nih.gov/22948144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inwardly rectifying currents in hair cells and supporting cells in the goldfish sacculus

1 reference

https://pubmed.ncbi.nlm.nih.gov/22948144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A conserved domain in the NH2 terminus important for assembly and functional expression of pacemaker channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/22948144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M112.375832

1 reference

31 January 2017

0 references

1 reference

31 January 2017

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