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Haploinsufficiency of the maspin tumor suppressor gene leads to hyperplastic lesions in prostate
scientific journal article
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scholarly article
1 reference
stated in
PubMed
PubMed ID
18593913
retrieved
31 January 2017
title
Haploinsufficiency of the maspin tumor suppressor gene leads to hyperplastic lesions in prostate
(English)
1 reference
stated in
PubMed
PubMed ID
18593913
retrieved
31 January 2017
main subject
haploinsufficiency
0 references
Serine (or cysteine) peptidase inhibitor, clade B, member 5
1 reference
stated in
GOA release 2020-03-11
author name string
Long-jiang Shao
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
18593913
retrieved
31 January 2017
Heidi Y. Shi
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
18593913
retrieved
31 January 2017
Gustavo Ayala
series ordinal
3
1 reference
stated in
PubMed
PubMed ID
18593913
retrieved
31 January 2017
David Rowley
series ordinal
4
1 reference
stated in
PubMed
PubMed ID
18593913
retrieved
31 January 2017
Ming Zhang
series ordinal
5
1 reference
stated in
PubMed
PubMed ID
18593913
retrieved
31 January 2017
language of work or name
English
0 references
publication date
1 July 2008
1 reference
stated in
PubMed
PubMed ID
18593913
retrieved
31 January 2017
published in
Cancer Research
1 reference
stated in
PubMed
PubMed ID
18593913
retrieved
31 January 2017
volume
68
1 reference
stated in
PubMed
PubMed ID
18593913
retrieved
31 January 2017
issue
13
1 reference
stated in
PubMed
PubMed ID
18593913
retrieved
31 January 2017
page(s)
5143–5151
1 reference
stated in
PubMed
PubMed ID
18593913
retrieved
31 January 2017
cites work
Nuclear cytokine-activated IKKalpha controls prostate cancer metastasis by repressing Maspin
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PubMed Central
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Mammary serine protease inhibitor (Maspin) binds directly to interferon regulatory factor 6: identification of a novel serpin partnership
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17 March 2017
Forkhead box A1 regulates prostate ductal morphogenesis and promotes epithelial cell maturation
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Focal adhesion kinase (FAK)-dependent regulation of S-phase kinase-associated protein-2 (Skp-2) stability. A novel mechanism regulating smooth muscle cell proliferation
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17 March 2017
Maspin plays an essential role in early embryonic development
1 reference
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PubMed Central
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17 March 2017
Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer
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17 March 2017
Pleiotrophic inhibition of pericellular urokinase-type plasminogen activator system by endogenous tumor suppressive maspin
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PubMed Central
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17 March 2017
Roles for Nkx3.1 in prostate development and cancer
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PubMed Central
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17 March 2017
Abrogation of the G2 cell cycle checkpoint associated with overexpression of HSIX1: a possible mechanism of breast carcinogenesis
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17 March 2017
Maspin is an intracellular serpin that partitions into secretory vesicles and is present at the cell surface
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518316
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17 March 2017
Cell adhesion: the molecular basis of tissue architecture and morphogenesis
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PubMed Central
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17 March 2017
Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals
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PubMed Central
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17 March 2017
The tumor suppressor maspin does not undergo the stressed to relaxed transition or inhibit trypsin-like serine proteases. Evidence that maspin is not a protease inhibitory serpin
1 reference
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PubMed Central
reference URL
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17 March 2017
Inhibitors of mammalian G1 cyclin-dependent kinases
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7 April 2017
The serpins are an expanding superfamily of structurally similar but functionally diverse proteins. Evolution, mechanism of inhibition, novel functions, and a revised nomenclature
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518316
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7 April 2017
Elucidating the function of secreted maspin: inhibiting cathepsin D-mediated matrix degradation
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518316
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29 September 2017
Maspin is physically associated with [beta]1 integrin regulating cell adhesion in mammary epithelial cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518316
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29 September 2017
Maspin retards cell detachment via a novel interaction with the urokinase-type plasminogen activator/urokinase-type plasminogen activator receptor system
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518316
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29 September 2017
Tumor-suppressive maspin regulates cell response to oxidative stress by direct interaction with glutathione S-transferase
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518316
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29 September 2017
Maspin mediates increased tumor cell apoptosis upon induction of the mitochondrial permeability transition
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518316
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29 September 2017
A critical role for p27kip1 gene dosage in a mouse model of prostate carcinogenesis.
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518316
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29 September 2017
Survey of genetically engineered mouse models for prostate cancer: analyzing the molecular basis of prostate cancer development, progression, and metastasis
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PubMed Central
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29 September 2017
p27Kip1 and cyclin D1 are necessary for focal adhesion kinase regulation of cell cycle progression in glioblastoma cells propagated in vitro and in vivo in the scid mouse brain
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PubMed Central
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29 September 2017
Epidermal growth factor receptor-dependent regulation of integrin-mediated signaling and cell cycle entry in epithelial cells
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29 September 2017
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29 September 2017
Distinct ligand binding sites in integrin α3β1 regulate matrix adhesion and cell–cell contact
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PubMed Central
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29 September 2017
Sufficiency of the reactive site loop of maspin for induction of cell-matrix adhesion and inhibition of cell invasion. Conversion of ovalbumin to a maspin-like molecule
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PubMed Central
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29 September 2017
Maspin expression inhibits osteolysis, tumor growth, and angiogenesis in a model of prostate cancer bone metastasis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518316
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29 September 2017
Hepsin and maspin are inversely expressed in laser capture microdissectioned prostate cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518316
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29 September 2017
Prostate tumor-stroma interaction: molecular mechanisms and opportunities for therapeutic targeting
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518316
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29 September 2017
The surface of prostate carcinoma DU145 cells mediates the inhibition of urokinase-type plasminogen activator by maspin.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518316
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29 September 2017
maspin suppresses the invasive phenotype of human breast carcinoma.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518316
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29 September 2017
E-Cadherin-dependent growth suppression is mediated by the cyclin-dependent kinase inhibitor p27(KIP1)
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518316
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29 September 2017
Adhesion-growth factor interactions during differentiation: an integrated biological response
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518316
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29 September 2017
Maspin acts at the cell membrane to inhibit invasion and motility of mammary and prostatic cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518316
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29 September 2017
Is plasminogen activator inhibitor-1 the molecular switch that governs urokinase receptor-mediated cell adhesion and release?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518316
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29 September 2017
Smooth muscle-epithelial interactions in normal and neoplastic prostatic development.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518316
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29 September 2017
Proliferating cell nuclear antigen and p21 are components of multiple cell cycle kinase complexes
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518316
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29 September 2017
Cyclins, Cdks, and cyclin kinase inhibitors.
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PubMed Central
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29 September 2017
Characterization of prostatic epithelial cell lines derived from transgenic adenocarcinoma of the mouse prostate (TRAMP) model.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518316
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3 June 2018
IKKalpha at the crossroads of inflammation and metastasis
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518316
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27 November 2018
Maspin functions as tumor suppressor by increasing cell adhesion to extracellular matrix in prostate tumor cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518316
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27 November 2018
Alpha5beta1 integrin mediates strong tissue cohesion
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518316
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27 November 2018
Blocking tumor growth, invasion, and metastasis by maspin in a syngeneic breast cancer model.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518316
retrieved
27 November 2018
Expression of the p53 and Maspin protein in primary prostate cancer: correlation with clinical features
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518316
retrieved
27 November 2018
Adhesion to fibronectin via beta1 integrins regulates p27kip1 levels and contributes to cell adhesion mediated drug resistance (CAM-DR).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518316
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27 November 2018
Efficacy of various natural and synthetic androgens to induce ductal branching morphogenesis in the developing anterior rat prostate
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518316
retrieved
27 November 2018
Maspin is an angiogenesis inhibitor
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18593913
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Maspin expression profile in human prostate cancer (CaP) and in vitro induction of Maspin expression by androgen ablation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18593913
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Maspin binds to urokinase-type and tissue-type plasminogen activator through exosite-exosite interactions
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18593913
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1158/0008-5472.CAN-08-0163
1 reference
stated in
PubMed
PubMed ID
18593913
retrieved
31 January 2017
PMCID
2518316
0 references
PubMed ID
18593913
1 reference
stated in
PubMed
PubMed ID
18593913
retrieved
31 January 2017
ResearchGate publication ID
5259366
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