(Q28585334)

English

In vivo mutagenesis of the Hoxb8 hexapeptide domain leads to dominant homeotic transformations that mimic the loss-of-function mutations in genes of the Hoxb cluster

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scholarly article

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31 January 2017

In vivo mutagenesis of the Hoxb8 hexapeptide domain leads to dominant homeotic transformations that mimic the loss-of-function mutations in genes of the Hoxb cluster (English)

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31 January 2017

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GOA release 2020-03-11

author name string

Olga Medina-Martínez

1

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31 January 2017

Ramiro Ramírez-Solis

2

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31 January 2017

language of work or name

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publication date

1 December 2003

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31 January 2017

Developmental Biology

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31 January 2017

264

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31 January 2017

1

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31 January 2017

77–90

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31 January 2017

The novel homeoprotein Prep1 modulates Pbx-Hox protein cooperativity

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https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

Prep1, a novel functional partner of Pbx proteins.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

Analysis of TALE superclass homeobox genes (MEIS, PBC, KNOX, Iroquois, TGIF) reveals a novel domain conserved between plants and animals

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

The DNA binding specificity of Ultrabithorax is modulated by cooperative interactions with extradenticle, another homeoprotein.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

The segment identity functions of Ultrabithorax are contained within its homeo domain and carboxy-terminal sequences

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

Pbx modulation of Hox homeodomain amino-terminal arms establishes different DNA-binding specificities across the Hox locus

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

Meis proteins are major in vivo DNA binding partners for wild-type but not chimeric Pbx proteins

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https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

Pbx proteins display hexapeptide-dependent cooperative DNA binding with a subset of Hox proteins

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https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

Ectopic expression of Hoxb-8 causes duplication of the ZPA in the forelimb and homeotic transformation of axial structures.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

Targeted mutations in hoxa-9 and hoxb-9 reveal synergistic interactions

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

Analysis of Hoxa7/Hoxb7 mutants suggests periodicity in the generation of the different sets of vertebrae

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

Two phases in the establishment of HOX expression domains.

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https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

The sequence specificity of homeodomain-DNA interaction

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

Analysis of LacZ reporter genes in transgenic embryos suggests the presence of several cis-acting regulatory elements in the murine Hoxb-6 gene

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

Functional specificity of the Antennapedia homeodomain

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https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

Homeodomain-DNA recognition

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

The specificities of Sex combs reduced and Antennapedia are defined by a distinct portion of each protein that includes the homeodomain.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

Positive cross-regulation and enhancer sharing: two mechanisms for specifying overlapping Hox expression patterns.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

Hoxb8 is required for normal grooming behavior in mice

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

Erratum: Introduction of a subtle mutation into the Hox-2.6 locus in embryonic stem cells

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https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

Gene splicing by overlap extension

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

Trimeric association of Hox and TALE homeodomain proteins mediates Hoxb2 hindbrain enhancer activity

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

The pentapeptide motif of Hox proteins is required for cooperative DNA binding with Pbx1, physically contacts Pbx1, and enhances DNA binding by Pbx1.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

HoxB8 requires its Pbx-interaction motif to block differentiation of primary myeloid progenitors and of most cell line models of myeloid differentiation

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

Hox genes in vertebrate development

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

A homeodomain substitution changes the regulatory specificity of the deformed protein in Drosophila embryos

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

Homeosis in the mouse induced by a null mutation in the Hox-3.1 gene

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

Mapping functional specificity in the Dfd and Ubx homeo domains

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

Homeotic transformations of murine vertebrae and concomitant alteration of Hox codes induced by retinoic acid

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

Cross-regulation in the mouse HoxB complex: the expression of Hoxb2 in rhombomere 4 is regulated by Hoxb1

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

Functional dissection of Ultrabithorax proteins in D. melanogaster.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

The developmental and molecular biology of genes that subdivide the body of Drosophila

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

Homeobox genes and axial patterning

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

A large targeted deletion of Hoxb1-Hoxb9 produces a series of single-segment anterior homeotic transformations

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

Pbx raises the DNA binding specificity but not the selectivity of antennapedia Hox proteins

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

The hexapeptide LFPWMR in Hoxb-8 is required for cooperative DNA binding with Pbx1 and Pbx2 proteins

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

Structure of a DNA-bound Ultrabithorax-Extradenticle homeodomain complex

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

Mutations in the Drosophila gene extradenticle affect the way specific homeo domain proteins regulate segmental identity

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

Cooperative interactions between HOX and PBX proteins mediated by a conserved peptide motif

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

Structure of a HoxB1-Pbx1 heterodimer bound to DNA: role of the hexapeptide and a fourth homeodomain helix in complex formation

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/pbx.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

Gene targeting in embryonic stem cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

Genomic DNA microextraction: A method to screen numerous samples

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

Genetic interaction between hoxb-5 and hoxb-6 is revealed by nonallelic noncomplementation

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

Region-specific expression of murine Hox genes implies the Hox code-mediated patterning of the digestive tract.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

The Abd-B-like Hox homeodomain proteins can be subdivided by the ability to form complexes with Pbx1a on a novel DNA target

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

Sequential activation of HOX2 homeobox genes by retinoic acid in human embryonal carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

Targeted inactivation of Hoxb8 affects survival of a spinal ganglion and causes aberrant limb reflexes

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

Hox gene products modulate the DNA binding activity of Pbx1 and Pbx2

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

Detection of messenger RNA by in situ hybridization to tissue sections and whole mounts

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

Functional dissection of the mouse Hox-a5 gene

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2003.07.020

7 January 2021

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10.1016/J.YDBIO.2003.07.020

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31 January 2017

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