(Q28585369)

31 January 2017

title

Mouse RS21-C6 is a mammalian 2'-deoxycytidine 5'-triphosphate pyrophosphohydrolase that prefers 5-iodocytosine (English)

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31 January 2017

main subject

DCTP pyrophosphatase 1

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GOA release 2020-03-11

author name string

Mari Nonaka

1

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31 January 2017

Daisuke Tsuchimoto

2

1 reference

31 January 2017

Kunihiko Sakumi

3

1 reference

31 January 2017

Yusaku Nakabeppu

4

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31 January 2017

language of work or name

English

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publication date

1 March 2009

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31 January 2017

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31 January 2017

volume

276

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31 January 2017

issue

6

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31 January 2017

page(s)

1654–1666

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The defense mechanisms in mammalian cells against oxidative damage in nucleic acids and their involvement in the suppression of mutagenesis and cell death

31 January 2017

cites work

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House cleaning, a part of good housekeeping

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Molecular genetics and structural biology of human MutT homolog, MTH1.

21 January 2018

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Analysis of MTH1 gene function in mice with targeted mutagenesis

21 January 2018

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Characterization of the structure and expression of mouse Itpa gene and its related sequences in the mouse genome.

21 January 2018

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Cloning, expression, and characterization of a human inosine triphosphate pyrophosphatase encoded by the itpa gene

21 January 2018

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Dimeric dUTPases, HisE, and MazG belong to a new superfamily of all-alpha NTP pyrophosphohydrolases with potential "house-cleaning" functions

21 January 2018

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Crystal structure of RS21-C6, involved in nucleoside triphosphate pyrophosphohydrolysis

21 January 2018

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Orf135 from Escherichia coli Is a Nudix hydrolase specific for CTP, dCTP, and 5-methyl-dCTP.

21 January 2018

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A putative house-cleaning enzyme encoded within an integron array: 1.8 A crystal structure defines a new MazG subtype

21 January 2018

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The crystal structure of a complex of Campylobacter jejuni dUTPase with substrate analogue sheds light on the mechanism and suggests the "basic module" for dimeric d(C/U)TPases

21 January 2018

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The crystal structure of Trypanosoma cruzi dUTPase reveals a novel dUTP/dUDP binding fold

21 January 2018

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p53R2-dependent ribonucleotide reduction provides deoxyribonucleotides in quiescent human fibroblasts in the absence of induced DNA damage.

21 January 2018

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Interrelations between substrate cycles and de novo synthesis of pyrimidine deoxyribonucleoside triphosphates in 3T6 cells

21 January 2018

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Molecular analysis of mutations in the hprt gene of V79 hamster fibroblasts: effects of imbalances in the dCTP, dGTP and dTTP pools

21 January 2018

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A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage

21 January 2018

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Mutation of RRM2B, encoding p53-controlled ribonucleotide reductase (p53R2), causes severe mitochondrial DNA depletion

21 January 2018

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Mitochondrial thymidine kinase and the enzymatic network regulating thymidine triphosphate pools in cultured human cells

21 January 2018

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Characterization of a dCTP transport activity reconstituted from human mitochondria.

21 January 2018

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Bromination of deoxycytidine by eosinophil peroxidase: a mechanism for mutagenesis by oxidative damage of nucleotide precursors

21 January 2018

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Production of brominating intermediates by myeloperoxidase. A transhalogenation pathway for generating mutagenic nucleobases during inflammation

21 January 2018

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Endogenous formation of novel halogenated 2'-deoxycytidine. Hypohalous acid-mediated DNA modification at the site of inflammation

21 January 2018

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Endogenous cytosine damage products alter the site selectivity of human DNA maintenance methyltransferase DNMT1.

21 January 2018

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Inflammation-mediated cytosine damage: a mechanistic link between inflammation and the epigenetic alterations in human cancers

21 January 2018

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5-halogenated pyrimidine lesions within a CpG sequence context mimic 5-methylcytosine by enhancing the binding of the methyl-CpG-binding domain of methyl-CpG-binding protein 2 (MeCP2).

21 January 2018

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Evidence for gene silencing by endogenous DNA methylation

21 January 2018

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Large-scale analysis of the human ubiquitin-related proteome

21 January 2018

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Hematopoietic tissue-specific expression of mouse Neil3 for endonuclease VIII-like protein

21 January 2018

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Human APE2 protein is mostly localized in the nuclei and to some extent in the mitochondria, while nuclear APE2 is partly associated with proliferating cell nuclear antigen

21 January 2018

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A naturally occurring truncated form of FosB that inhibits Fos/Jun transcriptional activity

21 January 2018

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An oxidized purine nucleoside triphosphatase, MTH1, suppresses cell death caused by oxidative stress

21 January 2018

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