(Q28586789)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10747846%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

title

Targeted inactivation of the isoprenylcysteine carboxyl methyltransferase gene causes mislocalization of K-Ras in mammalian cells (English)

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10747846%20AND%20SRC:MED&resulttype=core&format=json

Isoprenylcysteine carboxyl methyltransferase

5 November 2019

main subject

1 reference

GOA release 2020-03-11

author

Stephen G. Young

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10747846%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

author name string

Bergo MO

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10747846%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Leung GK

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10747846%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Ambroziak P

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10747846%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Otto JC

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10747846%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Casey PJ

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10747846%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

language of work or name

English

0 references

publication date

1 June 2000

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10747846%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

5 November 2019

published in

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10747846%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

volume

275

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10747846%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

page(s)

17605-17610

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10747846%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

issue

23

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10747846%20AND%20SRC:MED&resulttype=core&format=json

Protein prenylation: molecular mechanisms and functional consequences

5 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000079200

Endoplasmic reticulum membrane localization of Rce1p and Ste24p, yeast proteases involved in carboxyl-terminal CAAX protein processing and amino-terminal a-factor cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000079200

Posttranslational modification of the Ha-ras oncogene protein: evidence for a third class of protein carboxyl methyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000079200

Protein prenyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000079200

Inhibitors of Ras farnesyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000079200

Farnesyltransferase inhibitors versus Ras inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000079200

Nucleotide sequence of the yeast STE14 gene, which encodes farnesylcysteine carboxyl methyltransferase, and demonstration of its essential role in a-factor export

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000079200

The Saccharomyces cerevisiae prenylcysteine carboxyl methyltransferase Ste14p is in the endoplasmic reticulum membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000079200

Mammalian prenylcysteine carboxyl methyltransferase is in the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000079200

A single activity carboxyl methylates both farnesyl and geranylgeranyl cysteine residues

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000079200

Prenylated protein methyltransferases do not distinguish between farnesylated and geranylgeranylated substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000079200

Dislodgment and accelerated degradation of Ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000079200

Rescue of the En-1 mutant phenotype by replacement of En-1 with En-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000079200

Disruption of the acyl-CoA:cholesterol acyltransferase gene in mice: evidence suggesting multiple cholesterol esterification enzymes in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000079200

The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000079200

Production of homozygous mutant ES cells with a single targeting construct

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000079200

Cloning and characterization of a mammalian prenyl protein-specific protease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000079200

Disruption of the mouse Rce1 gene results in defective Ras processing and mislocalization of Ras within cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000079200

High-fidelity gene targeting in embryonic stem cells by using sequence replacement vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000079200

Animal models of human genetic diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000079200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000079200

Deficiency of a protein-repair enzyme results in the accumulation of altered proteins, retardation of growth, and fatal seizures in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000079200

Consecutive inactivation of both alleles of the pim-1 proto-oncogene by homologous recombination in embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000079200

All ras proteins are polyisoprenylated but only some are palmitoylated

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000079200

Fatty acylation of proteins: new insights into membrane targeting of myristoylated and palmitoylated proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000079200

Prenylation-dependent association of Ki-Ras with microtubules. Evidence for a role in subcellular trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000079200

Endomembrane trafficking of ras: the CAAX motif targets proteins to the ER and Golgi

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000079200

The carboxyl methyltransferase modifying G proteins is a metalloenzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C000079200

21 January 2018

Identifiers

DOI

10.1074/JBC.C000079200

2 references

Consolidated OpenCitations Corpus – April 2017

4086268

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10747846%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

4086268

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

2 references

4086268