(Q28586990)

English

mRNA decay factor AUF1 maintains normal aging, telomere maintenance, and suppression of senescence by activation of telomerase transcription

scientific journal article

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scholarly article

2 references

31 January 2017

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22633954%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

mRNA decay factor AUF1 maintains normal aging, telomere maintenance, and suppression of senescence by activation of telomerase transcription (English)

2 references

31 January 2017

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22633954%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

negative regulation of telomerase RNA reverse transcriptase activity

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

regulation of telomerase RNA reverse transcriptase activity

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

positive regulation of telomerase RNA reverse transcriptase activity

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

Heterogeneous nuclear ribonucleoprotein D

1 reference

GOA release 2020-03-11

2

1 reference

Europe PubMed Central

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2 February 2020

4

1 reference

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2 February 2020

Robert J Schneider

5

1 reference

Europe PubMed Central

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2 February 2020

author name string

Adam R Pont

1

1 reference

Europe PubMed Central

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2 February 2020

Susan J Hsiao

3

1 reference

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2 February 2020

publication date

24 May 2012

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2 February 2020

2 references

31 January 2017

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22633954%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

47

2 references

31 January 2017

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22633954%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1

2 references

31 January 2017

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22633954%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

5-15

1 reference

Europe PubMed Central

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2 February 2020

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3966316/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966316

17 March 2017

Linking functional decline of telomeres, mitochondria and stem cells during ageing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966316

17 March 2017

14-3-3sigma is a p37 AUF1-binding protein that facilitates AUF1 transport and AU-rich mRNA decay

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966316

17 March 2017

Tankyrase 2 poly(ADP-ribose) polymerase domain-deleted mice exhibit growth defects but have normal telomere length and capping

1 reference

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17 March 2017

The genetics of human longevity

1 reference

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17 March 2017

Ink4a/Arf expression is a biomarker of aging

1 reference

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17 March 2017

Resolution of sister telomere association is required for progression through mitosis

1 reference

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1 reference

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17 March 2017

Selective degradation of AU-rich mRNAs promoted by the p37 AUF1 protein isoform

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966316

17 March 2017

E2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpoints

1 reference

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17 March 2017

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

1 reference

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17 March 2017

Autophagy and aging

1 reference

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7 April 2017

Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing

1 reference

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7 April 2017

A DNA damage checkpoint response in telomere-initiated senescence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966316

7 April 2017

DNA damage foci at dysfunctional telomeres

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966316

7 April 2017

Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966316

7 April 2017

Cloning of mouse telomerase reverse transcriptase gene promoter and identification of proximal core promoter sequences essential for the expression of transgenes in cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966316

29 September 2017

Telomere measurement tools: Telometric produces biased estimates of telomere length

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966316

29 September 2017

Expression of p16(INK4a) prevents cancer and promotes aging in lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966316

29 September 2017

Telomeres in cancer and ageing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966316

29 September 2017

Making sense of G-quadruplex and i-motif functions in oncogene promoters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966316

29 September 2017

Tissue- and age-dependent expression of RNA-binding proteins that influence mRNA turnover and translation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966316

29 September 2017

Telomeres and immunological diseases of aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966316

29 September 2017

Formation of a unique end-to-end stacked pair of G-quadruplexes in the hTERT core promoter with implications for inhibition of telomerase by G-quadruplex-interactive ligands

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966316

29 September 2017

Auf1/Hnrnpd-deficient mice develop pruritic inflammatory skin disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966316

29 September 2017

Methods to detect biomarkers of cellular senescence: the senescence-associated beta-galactosidase assay

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966316

29 September 2017

Telomerase RNA levels limit the telomere length equilibrium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966316

29 September 2017

Endotoxic shock in AUF1 knockout mice mediated by failure to degrade proinflammatory cytokine mRNAs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966316

29 September 2017

Telomere-related genome instability in cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966316

29 September 2017

The biogenesis and regulation of telomerase holoenzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966316

29 September 2017

Short telomeres, even in the presence of telomerase, limit tissue renewal capacity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966316

29 September 2017

Structure of hnRNP D complexed with single-stranded telomere DNA and unfolding of the quadruplex by heterogeneous nuclear ribonucleoprotein D.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966316

29 September 2017

Increased stability of the p16 mRNA with replicative senescence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966316

29 September 2017

Distinct dosage requirements for the maintenance of long and short telomeres in mTert heterozygous mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966316

29 September 2017

Telomerase and differentiation in multicellular organisms: turn it off, turn it on, and turn it off again

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966316

29 September 2017

Distinct RNP complexes of shuttling hnRNP proteins with pre-mRNA and mRNA: candidate intermediates in formation and export of mRNA.

1 reference

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29 September 2017

Regulation of mRNA stability in mammalian cells

1 reference

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29 September 2017

Heterogeneous nuclear ribonucleoproteins as regulators of gene expression through interactions with the human thymidine kinase promoter

1 reference

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29 September 2017

Telomere length measurements using digital fluorescence microscopy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966316

29 September 2017

Disease states associated with telomerase deficiency appear earlier in mice with short telomeres

1 reference

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Nuclear import and export functions in the different isoforms of the AUF1/heterogeneous nuclear ribonucleoprotein protein family

1 reference

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3 June 2018

Telomere dysfunction provokes regional amplification and deletion in cancer genomes.

1 reference

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Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes

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27 November 2018

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1 reference

https://pubmed.ncbi.nlm.nih.gov/22633954

12 December 2020

based on heuristic

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Effect of TERT over-expression on the long-term transplantation capacity of hematopoietic stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22633954

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22633954

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.MOLCEL.2012.04.019

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

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2 February 2020

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22633954%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22633954%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

ResearchGate publication ID

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