(Q28587541)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16893422%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

title

Implication of the proprotein convertase NARC-1/PCSK9 in the development of the nervous system (English)

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16893422%20AND%20SRC:MED&resulttype=core&format=json

Proprotein convertase subtilisin/kexin type 9

28 December 2019

main subject

1 reference

Proprotein convertase subtilisin/kexin type 2

GOA release 2020-03-11

1 reference

Proprotein convertase subtilisin/kexin type 9

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

0 references

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16893422%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

David C Baranowski

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16893422%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

Nabil Seidah

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16893422%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

author name string

Steve Poirier

1

2 references

31 January 2017

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28 December 2019

Edwige Marcinkiewicz

3

2 references

31 January 2017

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28 December 2019

Joanne Paquin

4

2 references

31 January 2017

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28 December 2019

Benoit Cadieux

7

2 references

31 January 2017

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28 December 2019

Babykumari P Chitramuthu

5

1 reference

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28 December 2019

Hugh P J Bennett

8

1 reference

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28 December 2019

language of work or name

English

0 references

publication date

1 August 2006

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16893422%20AND%20SRC:MED&resulttype=core&format=json

Journal of Neurochemistry

28 December 2019

published in

2 references

31 January 2017

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28 December 2019

volume

98

2 references

31 January 2017

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28 December 2019

page(s)

838-850

1 reference

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28 December 2019

issue

3

2 references

31 January 2017

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Mutations in PCSK9 cause autosomal dominant hypercholesterolemia

28 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2006.03928.X

Comparative functional role of PC7 and furin in the processing of the HIV envelope glycoprotein gp160

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2006.03928.X

Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2006.03928.X

Adenoviral-mediated expression of Pcsk9 in mice results in a low-density lipoprotein receptor knockout phenotype

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2006.03928.X

Impaired fertility in mice deficient for the testicular germ-cell protease PC4

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2006.03928.X

Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2006.03928.X

Cleavage of sterol regulatory element-binding proteins (SREBPs) at site-1 requires interaction with SREBP cleavage-activating protein. Evidence from in vivo competition studies

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2006.03928.X

Molecular identification of the sterol-regulated luminal protease that cleaves SREBPs and controls lipid composition of animal cells

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2006.03928.X

Mammalian subtilisin/kexin isozyme SKI-1: A widely expressed proprotein convertase with a unique cleavage specificity and cellular localization

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2006.03928.X

The secretory proprotein convertase neural apoptosis-regulated convertase 1 (NARC-1): liver regeneration and neuronal differentiation

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2006.03928.X

Furin at the cutting edge: from protein traffic to embryogenesis and disease

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2006.03928.X

Effective targeted gene 'knockdown' in zebrafish

21 April 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03928.X

Novel mutations of the PCSK9 gene cause variable phenotype of autosomal dominant hypercholesterolemia

21 April 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03928.X

Dual regulation of the LDL receptor--some clarity and new questions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03928.X

PC1 and PC2 are proprotein convertases capable of cleaving proopiomelanocortin at distinct pairs of basic residues

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03928.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03928.X

Post-translational processing of beta-secretase (beta-amyloid-converting enzyme) and its ectodomain shedding. The pro- and transmembrane/cytosolic domains affect its cellular activity and amyloid-beta production

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03928.X

NARC-1/PCSK9 and its natural mutants: zymogen cleavage and effects on the low density lipoprotein (LDL) receptor and LDL cholesterol

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03928.X

Defective prodynorphin processing in mice lacking prohormone convertase PC2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03928.X

A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03928.X

Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03928.X

Low LDL cholesterol in individuals of African descent resulting from frequent nonsense mutations in PCSK9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03928.X

Alternative proteolytic processing of mouse mammary tumor virus superantigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03928.X

Statins upregulate PCSK9, the gene encoding the proprotein convertase neural apoptosis-regulated convertase-1 implicated in familial hypercholesterolemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03928.X

Heterologous processing of rat prosomatostatin to somatostatin-14 by PC2: requirement for secretory cell but not the secretion granule

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03928.X

The proprotein convertase PC5A and a metalloprotease are involved in the proteolytic processing of the neural adhesion molecule L1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03928.X

Proprotein convertases in tumor progression and malignancy: novel targets in cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03928.X

Developmental analysis of ceruloplasmin gene and liver formation in zebrafish.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03928.X

A spectrum of PCSK9 alleles contributes to plasma levels of low-density lipoprotein cholesterol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03928.X

RhoA/ROCK and Cdc42 regulate cell-cell contact and N-cadherin protein level during neurodetermination of P19 embryonal stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03928.X

The Lassa virus glycoprotein precursor GP-C is proteolytically processed by subtilase SKI-1/S1P.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03928.X

In vivo cellular and molecular mechanisms of neuronal apoptosis in the mammalian CNS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03928.X

Novel putative SREBP and LXR target genes identified by microarray analysis in liver of cholesterol-fed mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03928.X

Identification and characterization of Veph, a novel gene encoding a PH domain-containing protein expressed in the developing central nervous system of vertebrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03928.X

Post-transcriptional regulation of low density lipoprotein receptor protein by proprotein convertase subtilisin/kexin type 9a in mouse liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03928.X

Specific co-ordinated regulation of PC3 and PC2 gene expression with that of preproinsulin in insulin-producing beta TC3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03928.X

Proprotein and prohormone convertases: a family of subtilases generating diverse bioactive polypeptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03928.X

Precursor convertases in the secretory pathway, cytosol and extracellular milieu

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03928.X

A mutation in PCSK9 causing autosomal-dominant hypercholesterolemia in a Utah pedigree

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03928.X

Unique and conserved aspects of gut development in zebrafish.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03928.X

Proteolytic processing in the secretory pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03928.X

10.1111/J.1471-4159.2006.03928.X

21 January 2018

Identifiers

DOI

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16893422%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

2 references

31 January 2017