(Q28587867)

31 January 2017

title

A GRHL3-regulated repair pathway suppresses immune-mediated epidermal hyperplasia (English)

1 reference

Grainyhead like transcription factor 3

31 January 2017

main subject

1 reference

GOA release 2020-03-11

author name string

William M. Gordon

1

1 reference

31 January 2017

Michael D. Zeller

2

1 reference

31 January 2017

Rachel H. Klein

3

1 reference

31 January 2017

William R. Swindell

4

1 reference

31 January 2017

Hsiang Ho

5

1 reference

31 January 2017

Francisco Espetia

6

1 reference

31 January 2017

Johann E. Gudjonsson

7

1 reference

31 January 2017

Pierre F. Baldi

8

1 reference

31 January 2017

Bogi Andersen

9

1 reference

31 January 2017

language of work or name

English

0 references

publication date

1 December 2014

1 reference

Journal of Clinical Investigation

31 January 2017

published in

1 reference

31 January 2017

volume

124

1 reference

31 January 2017

issue

12

1 reference

31 January 2017

page(s)

5205–5218

1 reference

describes a project that uses

31 January 2017

limma

1 reference

Europe PubMed Central

22 June 2022

https://europepmc.org/article/PMC/4348962

inferred from PubMed Central ID database lookup

cites work

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Murine insulin growth factor-like (IGFL) and human IGFL1 proteins are induced in inflammatory skin conditions and bind to a novel tumor necrosis factor receptor family member, IGFLR1

17 March 2017

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Gene from a psoriasis susceptibility locus primes the skin for inflammation

17 March 2017

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Association analyses identify six new psoriasis susceptibility loci in the Chinese population

17 March 2017

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Epidermal wound repair is regulated by the planar cell polarity signaling pathway

17 March 2017

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Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities

17 March 2017

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17 March 2017

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Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways

17 March 2017

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17 March 2017

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The Grainyhead-like epithelial transactivator Get-1/Grhl3 regulates epidermal terminal differentiation and interacts functionally with LMO4

17 March 2017

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Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis

17 March 2017

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A homolog of Drosophila grainy head is essential for epidermal integrity in mice

17 March 2017

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Identification and characterization of Grainyhead-like epithelial transactivator (GET-1), a novel mammalian Grainyhead-like factor

17 March 2017

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A highly conserved novel family of mammalian developmental transcription factors related to Drosophila grainyhead

17 March 2017

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Klf4 is a transcription factor required for establishing the barrier function of the skin

17 March 2017

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Cellular dissection of psoriasis for transcriptome analyses and the post-GWAS era

17 March 2017

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Dominant mutations in GRHL3 cause Van der Woude Syndrome and disrupt oral periderm development

29 September 2017

1 reference

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The UCSC Genome Browser database: 2014 update

29 September 2017

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Modulation of epidermal transcription circuits in psoriasis: new links between inflammation and hyperproliferation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348962

Epidermal IL-15Rα acts as an endogenous antagonist of psoriasiform inflammation in mouse and man.

29 September 2017

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Dissecting the psoriasis transcriptome: inflammatory- and cytokine-driven gene expression in lesions from 163 patients

29 September 2017

1 reference

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Keratinocyte overexpression of IL-17C promotes psoriasiform skin inflammation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348962

Cross-study homogeneity of psoriasis gene expression in skin across a large expression range

29 September 2017

1 reference

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The IL-23/T17 pathogenic axis in psoriasis is amplified by keratinocyte responses

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348962

Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348962

GRHL3/GET1 and trithorax group members collaborate to activate the epidermal progenitor differentiation program

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348962

Expanding the psoriasis disease profile: interrogation of the skin and serum of patients with moderate-to-severe psoriasis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348962

New insights of T cells in the pathogenesis of psoriasis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348962

The Grainyhead transcription factor Grhl3/Get1 suppresses miR-21 expression and tumorigenesis in skin: modulation of the miR-21 target MSH2 by RNA-binding protein DND1

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348962

Cyber-T web server: differential analysis of high-throughput data

29 September 2017

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Heterogeneity of inflammatory and cytokine networks in chronic plaque psoriasis

29 September 2017

1 reference

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Urea uptake enhances barrier function and antimicrobial defense in humans by regulating epidermal gene expression

29 September 2017

1 reference

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29 September 2017

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Epidermal ablation of Dlx3 is linked to IL-17-associated skin inflammation

29 September 2017

1 reference

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Genome-wide expression profiling of five mouse models identifies similarities and differences with human psoriasis.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348962

Grainyhead and Zelda compete for binding to the promoters of the earliest-expressed Drosophila genes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348962

Expression of the homeobox gene, HOPX, is modulated by cell differentiation in human keratinocytes and is involved in the expression of differentiation markers

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348962

Local protease signaling contributes to neural tube closure in the mouse embryo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348962

Deletion of the late cornified envelope LCE3B and LCE3C genes as a susceptibility factor for psoriasis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348962

Type I interferon: potential therapeutic target for psoriasis?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348962

Grainyhead-like factor Get1/Grhl3 regulates formation of the epidermal leading edge during eyelid closure

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348962

Transcription factors GATA-4 and GATA-6 in normal and neoplastic human gastrointestinal mucosa

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348962

Innate immunity and antimicrobial defense systems in psoriasis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348962

Resident skin cells in psoriasis: a special look at the pathogenetic functions of keratinocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348962

Immunopathogenesis and role of T cells in psoriasis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348962

Defective glycerol metabolism in aquaporin 9 (AQP9) knockout mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348962

Crim1KST264/KST264 mice display a disruption of the Crim1 gene resulting in perinatal lethality with defects in multiple organ systems

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348962

Cell biology: master regulators of sealing and healing

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348962

Differential regulation of a fibroblast growth factor-binding protein during skin carcinogenesis and wound healing.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348962

DNA methylation dynamics during in vivo differentiation of blood and skin stem cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348962

Genetics of psoriasis: evidence for epistatic interaction between skin barrier abnormalities and immune deviation.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348962

Generalized exacerbation of psoriasis associated with imiquimod cream treatment of superficial basal cell carcinomas

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348962

Psoriasis induced by topical imiquimod

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348962

T-cell activation is potentiated by cytokines released by lesional psoriatic, but not normal, epidermis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348962

Guselkumab (an IL-23-specific mAb) demonstrates clinical and molecular response in patients with moderate-to-severe psoriasis.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348962

A large-scale screen for coding variants predisposing to psoriasis

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348962

Expression of IL-33 in the epidermis: The mechanism of induction by IL-17.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348962

Abnormal epidermal barrier in the pathogenesis of psoriasis

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348962

IL-22 is required for imiquimod-induced psoriasiform skin inflammation in mice

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348962

Targeting of the tumor suppressor GRHL3 by a miR-21-dependent proto-oncogenic network results in PTEN loss and tumorigenesis.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348962

IL-21 promotes skin recruitment of CD4(+) cells and drives IFN-γ-dependent epidermal hyperplasia

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348962

Expression of interleukin (IL)-1 family members upon stimulation with IL-17 differs in keratinocytes derived from patients with psoriasis and healthy donors.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348962

Imiquimod-induced psoriasis-like skin inflammation in mice is mediated via the IL-23/IL-17 axis.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348962

Generalized psoriasis induced by topical treatment of actinic keratosis with imiquimod

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348962

Epithelial Bmpr1a regulates differentiation and proliferation in postnatal hair follicles and is essential for tooth development

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348962

Tape stripping and sodium dodecyl sulfate treatment increase the molecular weight cutoff of polyethylene glycol penetration across murine skin

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348962

Expression of a binding protein for FGF is associated with epithelial development and skin carcinogenesis

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348962

Gene Expression Profiles Normalized in Psoriatic Skin by Treatment with Brodalumab, a Human Anti-IL-17 Receptor Monoclonal Antibody

27 November 2018

1 reference

12 December 2020

IL-23-mediated epidermal hyperplasia is dependent on IL-6

1 reference

12 December 2020

S100A8 and S100A9 are messengers in the crosstalk between epidermis and dermis modulating a psoriatic milieu in human skin

1 reference

12 December 2020

TGFβ1, an epidermal controller of skin dendritic cell homeostasis

1 reference

12 December 2020

Stratum corneum structure and function correlates with phenotype in psoriasis

1 reference

12 December 2020

Interleukin-1: A key inflammatory mediator in psoriasis?

1 reference

12 December 2020

Cooperation between GATA4 and TGF-beta signaling regulates intestinal epithelial gene expression

1 reference

12 December 2020

Identifiers

1 reference

31 January 2017

0 references

1 reference