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Decreased lipid synthesis in livers of mice with disrupted Site-1 protease gene
scientific journal article
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instance of
scholarly article
1 reference
stated in
PubMed
PubMed ID
11717426
retrieved
31 January 2017
title
Decreased lipid synthesis in livers of mice with disrupted Site-1 protease gene
(English)
1 reference
stated in
PubMed
PubMed ID
11717426
retrieved
31 January 2017
main subject
Membrane-bound transcription factor peptidase, site 1
1 reference
stated in
GOA release 2020-03-11
author name string
J. Yang
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
11717426
retrieved
31 January 2017
J. L. Goldstein
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
11717426
retrieved
31 January 2017
R. E. Hammer
series ordinal
3
1 reference
stated in
PubMed
PubMed ID
11717426
retrieved
31 January 2017
Y. A. Moon
series ordinal
4
1 reference
stated in
PubMed
PubMed ID
11717426
retrieved
31 January 2017
M. S. Brown
series ordinal
5
1 reference
stated in
PubMed
PubMed ID
11717426
retrieved
31 January 2017
J. D. Horton
series ordinal
6
1 reference
stated in
PubMed
PubMed ID
11717426
retrieved
31 January 2017
language of work or name
English
0 references
publication date
20 November 2001
1 reference
stated in
PubMed
PubMed ID
11717426
retrieved
31 January 2017
published in
Proceedings of the National Academy of Sciences of the United States of America
1 reference
stated in
PubMed
PubMed ID
11717426
retrieved
31 January 2017
volume
98
1 reference
stated in
PubMed
PubMed ID
11717426
retrieved
31 January 2017
page(s)
13607–13612
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stated in
PubMed
PubMed ID
11717426
retrieved
31 January 2017
issue
24
1 reference
stated in
PubMed
PubMed ID
11717426
retrieved
31 January 2017
cites work
SREBP cleavage-activating protein (SCAP) is required for increased lipid synthesis in liver induced by cholesterol deprivation and insulin elevation
1 reference
stated in
PubMed Central
reference URL
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Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta
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PubMed Central
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17 March 2017
Transport-dependent proteolysis of SREBP: relocation of site-1 protease from Golgi to ER obviates the need for SREBP transport to Golgi
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PubMed Central
reference URL
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17 March 2017
A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood
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PubMed Central
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17 March 2017
Autocatalytic processing of site-1 protease removes propeptide and permits cleavage of sterol regulatory element-binding proteins
1 reference
stated in
PubMed Central
reference URL
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17 March 2017
Molecular identification of the sterol-regulated luminal protease that cleaves SREBPs and controls lipid composition of animal cells
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PubMed Central
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17 March 2017
Complementation cloning of S2P, a gene encoding a putative metalloprotease required for intramembrane cleavage of SREBPs
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PubMed Central
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17 March 2017
Cleavage of sterol regulatory element-binding proteins (SREBPs) at site-1 requires interaction with SREBP cleavage-activating protein. Evidence from in vivo competition studies
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PubMed Central
reference URL
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17 March 2017
Inducible inactivation of hepatic LRP gene by cre-mediated recombination confirms role of LRP in clearance of chylomicron remnants
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PubMed Central
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17 March 2017
Elevated levels of SREBP-2 and cholesterol synthesis in livers of mice homozygous for a targeted disruption of the SREBP-1 gene
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61088
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17 March 2017
The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor
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PubMed Central
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17 March 2017
Structure of the human gene encoding sterol regulatory element binding protein 2 (SREBF2)
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17 March 2017
Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells
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PubMed Central
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17 March 2017
Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery
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7 April 2017
Inducible gene targeting in mice
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PubMed Central
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7 April 2017
Protamine-Cre recombinase transgenes efficiently recombine target sequences in the male germ line of mice, but not in embryonic stem cells
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PubMed Central
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7 April 2017
Expression of sterol regulatory element-binding protein 1c (SREBP-1c) mRNA in rat hepatoma cells requires endogenous LXR ligands
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61088
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29 September 2017
Regulated step in cholesterol feedback localized to budding of SCAP from ER membranes
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61088
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29 September 2017
Promoter analysis of the mouse sterol regulatory element-binding protein-1c gene
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61088
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29 September 2017
Insulin selectively increases SREBP-1c mRNA in the livers of rats with streptozotocin-induced diabetes
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61088
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29 September 2017
Disruption of LDL receptor gene in transgenic SREBP-1a mice unmasks hyperlipidemia resulting from production of lipid-rich VLDL
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61088
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29 September 2017
Second-site cleavage in sterol regulatory element-binding protein occurs at transmembrane junction as determined by cysteine panning
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61088
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29 September 2017
Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element-binding protein-2.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61088
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29 September 2017
Regulation of sterol regulatory element binding proteins in livers of fasted and refed mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61088
retrieved
29 September 2017
Cleavage site for sterol-regulated protease localized to a leu-Ser bond in the lumenal loop of sterol regulatory element-binding protein-2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61088
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29 September 2017
Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61088
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29 September 2017
Sterol-dependent transcriptional regulation of sterol regulatory element-binding protein-2.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61088
retrieved
29 September 2017
Independent regulation of sterol regulatory element-binding proteins 1 and 2 in hamster liver
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61088
retrieved
29 September 2017
Secreted site-1 protease cleaves peptides corresponding to luminal loop of sterol regulatory element-binding proteins.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61088
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3 June 2018
Isolation of cholesterol-requiring mutant Chinese hamster ovary cells with defects in cleavage of sterol regulatory element-binding proteins at site 1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61088
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3 June 2018
Functional analysis of secreted and transmembrane proteins critical to mouse development.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61088
retrieved
27 November 2018
Failure to cleave sterol regulatory element-binding proteins (SREBPs) causes cholesterol auxotrophy in Chinese hamster ovary cells with genetic absence of SREBP cleavage-activating protein.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=61088
retrieved
27 November 2018
19 Receptor-mediated endocytosis of low-density lipoprotein in cultured cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/11717426
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1073/PNAS.201524598
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2566192
ADS bibcode
2001PNAS...9813607Y
0 references
OpenCitations bibliographic resource ID
2566192
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2566192
PMCID
61088
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2566192
PubMed ID
11717426
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2566192
ResearchGate publication ID
11638804
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