(Q28589006)

31 January 2017

title

Increased constitutive c-Jun N-terminal kinase signaling in mice lacking glutathione S-transferase Pi (English)

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Glutathione S-transferase, pi 1

31 January 2017

main subject

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GOA release 2020-03-11

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Robert Elsby

1

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31 January 2017

Neil R. Kitteringham

2

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31 January 2017

Christopher E. Goldring

3

1 reference

31 January 2017

Cerys A. Lovatt

4

1 reference

31 January 2017

Mark Chamberlain

5

1 reference

31 January 2017

Colin J. Henderson

6

1 reference

31 January 2017

C. Roland Wolf

7

1 reference

31 January 2017

B. Kevin Park

8

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31 January 2017

language of work or name

English

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publication date

20 June 2003

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Journal of Biological Chemistry

31 January 2017

published in

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31 January 2017

volume

278

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31 January 2017

issue

25

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31 January 2017

page(s)

22243–22249

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The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance

31 January 2017

cites work

1 reference

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A bird's eye view of the glutathione transferase field

21 January 2018

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Protein expression profiling of glutathione S-transferase pi null mice as a strategy to identify potential markers of resistance to paracetamol-induced toxicity in the liver

21 January 2018

1 reference

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Immunohistological analysis of glutathione transferase A4 distribution in several human tissues using a specific polyclonal antibody

21 January 2018

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Regulation of JNK signaling by GSTp

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M301211200

Glutathione S-transferase P1-1 (GSTP1-1) inhibits c-Jun N-terminal kinase (JNK1) signaling through interaction with the C terminus

21 January 2018

1 reference

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Glutathione S-transferase Pi is a dopamine-inducible suppressor of dopamine-induced apoptosis in PC12 cells

21 January 2018

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Glutathione S-transferase mu modulates the stress-activated signals by suppressing apoptosis signal-regulating kinase 1

21 January 2018

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The stress-activated protein kinase subfamily of c-Jun kinases

21 January 2018

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Transcription factor ATF2 regulation by the JNK signal transduction pathway

21 January 2018

1 reference

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Nrf2 and Nrf1 in association with Jun proteins regulate antioxidant response element-mediated expression and coordinated induction of genes encoding detoxifying enzymes

21 January 2018

1 reference

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Nrf2 and c-Jun regulation of antioxidant response element (ARE)-mediated expression and induction of gamma-glutamylcysteine synthetase heavy subunit gene

21 January 2018

1 reference

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High sensitivity of Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzymes and antioxidant genes

21 January 2018

1 reference

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Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice

21 January 2018

1 reference

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Activation of mitogen-activated protein kinase pathways induces antioxidant response element-mediated gene expression via a Nrf2-dependent mechanism

21 January 2018

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Induction of xenobiotic enzymes by the MAP kinase pathway and the antioxidant or electrophile response element (ARE/EpRE).

21 January 2018

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Antioxidants and oxidants regulated signal transduction pathways

21 January 2018

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Regulatory mechanisms of cellular response to oxidative stress

21 January 2018

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An important function of Nrf2 in combating oxidative stress: detoxification of acetaminophen

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301211200

Increased skin tumorigenesis in mice lacking pi class glutathione S-transferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301211200

Increased resistance to acetaminophen hepatotoxicity in mice lacking glutathione S-transferase Pi.

21 January 2018

1 reference

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N-Hydroxylation of dapsone by multiple enzymes of cytochrome P450: implications for inhibition of haemotoxicity

21 January 2018

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21 January 2018

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Activation of transcription factors by drugs inducing oxidative stress in rat liver.

21 January 2018

1 reference

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Transcriptional activation of the UDP-glucuronosyltransferase 1A7 gene in rat liver by aryl hydrocarbon receptor ligands and oltipraz.

21 January 2018

1 reference

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Comparison of oxidative stress response parameters in newborn mouse liver versus simian virus 40 (SV40)-transformed hepatocyte cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301211200

An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301211200

Induction of cellular antioxidative stress genes through heterodimeric transcription factor Nrf2/small Maf by antirheumatic gold(I) compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301211200

Comparison of the levels of enzymes involved in drug metabolism between transgenic or gene-knockout and the parental mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301211200

Mutational status of the p53 gene modulates the basal level of jun N-terminal kinase and its inducibility by ultraviolet irradiation in A1-5 rat fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301211200

Targeted disruption of the microsomal epoxide hydrolase gene. Microsomal epoxide hydrolase is required for the carcinogenic activity of 7,12-dimethylbenz[a]anthracene

21 January 2018

1 reference

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Role of cytochrome P450 1a1 and 1b1 in the metabolic activation of 7,12-dimethylbenz[a]anthracene and the effects of naturally occurring furanocoumarins on skin tumor initiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301211200

Hepatocellular response to chemical stress in CD-1 mice: induction of early genes and gamma-glutamylcysteine synthetase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301211200

Molecular genetic basis for deficient acetaminophen glucuronidation by cats: UGT1A6 is a pseudogene, and evidence for reduced diversity of expressed hepatic UGT1A isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301211200

Oltipraz-induced amelioration of acetaminophen hepatotoxicity in hamsters. II. Competitive shunt in metabolism via glucuronidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301211200

Differential induction of heme oxygenase-1 in macrophages and hepatocytes during acetaminophen-induced hepatotoxicity in the rat: effects of hemin and biliverdin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301211200

21 January 2018

Identifiers

DOI

10.1074/JBC.M301211200

1 reference

31 January 2017

1 reference