(Q28592092)

31 January 2017

title

Regulation of B-lymphocyte negative and positive selection by tyrosine phosphatase CD45 (English)

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Protein tyrosine phosphatase, receptor type, C

31 January 2017

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GOA release 2020-03-11

author name string

J. G. Cyster

1

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31 January 2017

J. I. Healy

2

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31 January 2017

K. Kishihara

3

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31 January 2017

T. W. Mak

4

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31 January 2017

M. L. Thomas

5

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31 January 2017

C. C. Goodnow

6

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31 January 2017

language of work or name

English

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publication date

23 May 1996

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31 January 2017

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31 January 2017

volume

381

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31 January 2017

issue

6580

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31 January 2017

page(s)

325–328

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Normal B lymphocyte development but impaired T cell maturation in CD45-exon6 protein tyrosine phosphatase-deficient mice

31 January 2017

cites work

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7 January 2021

Evidence that the leukocyte-common antigen is required for antigen-induced T lymphocyte proliferation

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7 January 2021

Tyrosine phosphatase CD45 is essential for coupling T-cell antigen receptor to the phosphatidyl inositol pathway

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7 January 2021

The CD45 protein tyrosine phosphatase is required for the completion of the activation program leading to lymphokine production in the Jurkat human T cell line

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7 January 2021

The CD45 tyrosine phosphatase regulates phosphotyrosine homeostasis and its loss reveals a novel pattern of late T cell receptor-induced Ca2+ oscillations

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7 January 2021

Regulation of B cell antigen receptor signal transduction and phosphorylation by CD45.

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7 January 2021

Antigen receptor-initiated growth inhibition is blocked in CD45-loss variants of a mature B lymphoma, with limited effects on apoptosis

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7 January 2021

Competition for follicular niches excludes self-reactive cells from the recirculating B-cell repertoire.

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7 January 2021

Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice.

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7 January 2021

Induction of self-tolerance in T cells but not B cells of transgenic mice expressing little self antigen.

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7 January 2021

Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens

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7 January 2021

Censoring of self-reactive B cells with a range of receptor affinities in transgenic mice expressing heavy chains for a lysozyme-specific antibody

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7 January 2021

Antigen-driven selection of virgin and memory B cells

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7 January 2021

Biased expression of JH-proximal VH genes occurs in the newly generated repertoire of neonatal and adult mice

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7 January 2021

Most peripheral B cells in mice are ligand selected

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7 January 2021

T cell receptor antagonist peptides induce positive selection

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7 January 2021

Evidence for a differential avidity model of T cell selection in the thymus

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7 January 2021

Positive and negative thymocyte selection induced by different concentrations of a single peptide

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7 January 2021

Multiple defects in the immune system of Lyn-deficient mice, culminating in autoimmune disease

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7 January 2021

Impaired proliferation of peripheral B cells and indication of autoimmune disease in lyn-deficient mice

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7 January 2021

Requirements for Phosphorylation of Map Kinase During Meiosis in Xenopus Oocytes

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7 January 2021

Regulation of pp90rsk phosphorylation and S6 phosphotransferase activity in Swiss 3T3 cells by growth factor-, phorbol ester-, and cyclic AMP-mediated signal transduction

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7 January 2021

Immunoglobulin signal transduction guides the specificity of B cell-T cell interactions and is blocked in tolerant self-reactive B cells

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7 January 2021

Elimination of self-reactive B lymphocytes proceeds in two stages: arrested development and cell death.

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7 January 2021

Identifiers

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Dimensions Publication ID

31 January 2017

1051959387

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