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Agrin isoforms with distinct amino termini: differential expression, localization, and function
scientific journal article
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scholarly article
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PubMed
PubMed ID
11018052
retrieved
31 January 2017
title
Agrin isoforms with distinct amino termini: differential expression, localization, and function
(English)
1 reference
stated in
PubMed
PubMed ID
11018052
retrieved
31 January 2017
main subject
Agrin
1 reference
stated in
GOA release 2020-03-11
author name string
R. W. Burgess
series ordinal
1
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stated in
PubMed
PubMed ID
11018052
retrieved
31 January 2017
W. C. Skarnes
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
11018052
retrieved
31 January 2017
J. R. Sanes
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3
1 reference
stated in
PubMed
PubMed ID
11018052
retrieved
31 January 2017
language of work or name
English
0 references
publication date
2 October 2000
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stated in
PubMed
PubMed ID
11018052
retrieved
31 January 2017
published in
Journal of Cell Biology
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stated in
PubMed
PubMed ID
11018052
retrieved
31 January 2017
volume
151
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stated in
PubMed
PubMed ID
11018052
retrieved
31 January 2017
page(s)
41–52
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stated in
PubMed
PubMed ID
11018052
retrieved
31 January 2017
issue
1
1 reference
stated in
PubMed
PubMed ID
11018052
retrieved
31 January 2017
cites work
Alternatively spliced isoforms of nerve- and muscle-derived agrin: their roles at the neuromuscular junction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189804
retrieved
17 March 2017
Distinct phenotypes of mutant mice lacking agrin, MuSK, or rapsyn
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189804
retrieved
17 March 2017
Synapse formation by hippocampal neurons from agrin-deficient mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189804
retrieved
17 March 2017
Primary structure and high expression of human agrin in basement membranes of adult lung and kidney
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189804
retrieved
17 March 2017
Agrin is a major heparan sulfate proteoglycan in the human glomerular basement membrane
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189804
retrieved
17 March 2017
Agrin binds to the nerve-muscle basal lamina via laminin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189804
retrieved
17 March 2017
Alternative splicing of agrin regulates its binding to heparin alpha-dystroglycan, and the cell surface
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189804
retrieved
17 March 2017
Defective neuromuscular synaptogenesis in agrin-deficient mutant mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189804
retrieved
17 March 2017
Capturing genes encoding membrane and secreted proteins important for mouse development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189804
retrieved
17 March 2017
A new method for predicting signal sequence cleavage sites
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189804
retrieved
17 March 2017
Structure and expression of a rat agrin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189804
retrieved
17 March 2017
Structure and chromosomal localization of the mammalian agrin gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189804
retrieved
17 March 2017
A single protocol to detect transcripts of various types and expression levels in neural tissue and cultured cells: in situ hybridization using digoxigenin-labelled cRNA probes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189804
retrieved
7 April 2017
Isolation and characterization of a cDNA that encodes an agrin homolog in the marine ray.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189804
retrieved
29 September 2017
Glomerular heparan sulfate alterations: mechanisms and relevance for proteinuria
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189804
retrieved
29 September 2017
Expression, distribution and ultrastructural localization of the synapse-organizing molecule agrin in the mature avian retina
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189804
retrieved
29 September 2017
Integrins mediate adhesion to agrin and modulate agrin signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189804
retrieved
29 September 2017
Rapid sequence analysis of gene trap integrations to generate a resource of insertional mutations in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189804
retrieved
29 September 2017
Alternative splicing of agrin alters its binding to heparin, dystroglycan, and the putative agrin receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189804
retrieved
29 September 2017
An amino-terminal extension is required for the secretion of chick agrin and its binding to extracellular matrix
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189804
retrieved
29 September 2017
Acetylcholine receptor-aggregating activity of agrin isoforms and mapping of the active site
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189804
retrieved
29 September 2017
Use of a recombinant retrovirus to study post-implantation cell lineage in mouse embryos
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189804
retrieved
29 September 2017
The agrin hypothesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189804
retrieved
29 September 2017
Current status of the structural and functional basis of glomerular filtration and proteinuria.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189804
retrieved
29 September 2017
Agrin mediates cell contact-induced acetylcholine receptor clustering
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189804
retrieved
29 September 2017
The agrin gene codes for a family of basal lamina proteins that differ in function and distribution
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189804
retrieved
29 September 2017
cDNA that encodes active agrin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189804
retrieved
29 September 2017
Interaction of agrin with laminin requires a coiled-coil conformation of the agrin-binding site within the laminin gamma1 chain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189804
retrieved
3 June 2018
Evidence of an agrin receptor in cortical neurons
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189804
retrieved
3 June 2018
Formation of functional synaptic connections between cultured cortical neurons from agrin-deficient mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189804
retrieved
3 June 2018
Neural agrin induces ectopic postsynaptic specializations in innervated muscle fibers.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189804
retrieved
3 June 2018
Distribution and substrate properties of agrin, a heparan sulfate proteoglycan of developing axonal pathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189804
retrieved
3 June 2018
Expression of agrin in the developing and adult rat brain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189804
retrieved
3 June 2018
Axonal targeting of agrin in cultured rat dorsal horn neurons.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189804
retrieved
3 June 2018
Agrin is synthesized by retinal cells and colocalizes with gephyrin [corrected]
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189804
retrieved
3 June 2018
Developmental regulation of highly active alternatively spliced forms of agrin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189804
retrieved
3 June 2018
Brain extract induces synaptic characteristics in the basal lamina of cultured myotubes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189804
retrieved
3 June 2018
Identification of a transmembrane glycoprotein specific for secretory vesicles of neural and endocrine cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189804
retrieved
3 June 2018
RNA splicing regulates agrin-mediated acetylcholine receptor clustering activity on cultured myotubes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189804
retrieved
3 June 2018
Abnormal synapse formation in agrin-depleted hippocampal neurons.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189804
retrieved
27 November 2018
Agrin-induced postsynaptic-like apparatus in skeletal muscle fibers in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189804
retrieved
27 November 2018
Agrin accumulates in the brain microvascular basal lamina during development of the blood-brain barrier.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189804
retrieved
27 November 2018
The ability of agrin to cluster AChRs depends on alternative splicing and on cell surface proteoglycans
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189804
retrieved
27 November 2018
Localization and alternative splicing of agrin mRNA in adult rat brain: transcripts encoding isoforms that aggregate acetylcholine receptors are not restricted to cholinergic regions.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189804
retrieved
27 November 2018
Identification of a novel alternatively spliced agrin mRNA that is preferentially expressed in non-neuronal cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189804
retrieved
27 November 2018
Agrin mRNA variants are differentially regulated in developing chick embryo spinal cord and sensory ganglia.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189804
retrieved
27 November 2018
Tissue- and age-specific expression patterns of alternatively spliced agrin mRNA transcripts in embryonic rat suggest novel developmental roles.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189804
retrieved
27 November 2018
Alternative RNA splicing that determines agrin activity regulates binding to heparin and alpha-dystroglycan
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/11018052
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Specific agrin isoforms induce cAMP response element binding protein phosphorylation in hippocampal neurons.
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/11018052
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1083/JCB.151.1.41
0 references
PMCID
2189804
0 references
PubMed ID
11018052
1 reference
stated in
PubMed
PubMed ID
11018052
retrieved
31 January 2017
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