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Neutrophil-specific deletion of Syk kinase results in reduced host defense to bacterial infection
scientific journal article
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scholarly article
1 reference
stated in
PubMed
PubMed ID
19797524
retrieved
31 January 2017
title
Neutrophil-specific deletion of Syk kinase results in reduced host defense to bacterial infection
(English)
1 reference
stated in
PubMed
PubMed ID
19797524
retrieved
31 January 2017
main subject
Spleen tyrosine kinase
1 reference
stated in
GOA release 2020-03-11
author name string
Jessica A. Van Ziffle
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
19797524
retrieved
31 January 2017
Clifford A. Lowell
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
19797524
retrieved
31 January 2017
language of work or name
English
0 references
publication date
26 November 2009
1 reference
stated in
PubMed
PubMed ID
19797524
retrieved
31 January 2017
published in
Blood
1 reference
stated in
PubMed
PubMed ID
19797524
retrieved
31 January 2017
volume
114
1 reference
stated in
PubMed
PubMed ID
19797524
retrieved
31 January 2017
page(s)
4871–4882
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stated in
PubMed
PubMed ID
19797524
retrieved
31 January 2017
issue
23
1 reference
stated in
PubMed
PubMed ID
19797524
retrieved
31 January 2017
cites work
ITAM signaling by Vav family Rho guanine nucleotide exchange factors regulates interstitial transit rates of neutrophils in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786293
retrieved
17 March 2017
Integrin signaling in neutrophils and macrophages uses adaptors containing immunoreceptor tyrosine-based activation motifs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786293
retrieved
17 March 2017
The shedding activity of ADAM17 is sequestered in lipid rafts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786293
retrieved
17 March 2017
Vav GEFs are required for beta2 integrin-dependent functions of neutrophils
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786293
retrieved
17 March 2017
Pattern recognition by TREM-2: binding of anionic ligands
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786293
retrieved
17 March 2017
Essential role of Src-family protein tyrosine kinases in NF-kappaB activation during B cell development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786293
retrieved
17 March 2017
Leukocyte adhesion deficiency syndromes: adhesion and tethering defects involving beta 2 integrins and selectin ligands
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786293
retrieved
17 March 2017
Cutting edge: inflammatory responses can be triggered by TREM-1, a novel receptor expressed on neutrophils and monocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786293
retrieved
17 March 2017
p40(phox) is phosphorylated on threonine 154 and serine 315 during activation of the phagocyte NADPH oxidase. Implication of a protein kinase c-type kinase in the phosphorylation process
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786293
retrieved
17 March 2017
A critical role for Syk in signal transduction and phagocytosis mediated by Fcgamma receptors on macrophages
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786293
retrieved
17 March 2017
Mouse model of X-linked chronic granulomatous disease, an inherited defect in phagocyte superoxide production
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786293
retrieved
17 March 2017
Syk tyrosine kinase required for mouse viability and B-cell development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786293
retrieved
17 March 2017
Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786293
retrieved
17 March 2017
Adhesion-promoting receptors on human macrophages recognize Escherichia coli by binding to lipopolysaccharide
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786293
retrieved
17 March 2017
Pattern recognition: recent insights from Dectin-1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786293
retrieved
29 September 2017
CARD9 signaling in the innate immune response
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786293
retrieved
29 September 2017
CD18-dependent activation of the neutrophil NADPH oxidase during phagocytosis of Escherichia coli or Staphylococcus aureus is regulated by class III but not class I or II PI3Ks
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786293
retrieved
29 September 2017
Increased TLR responses in dendritic cells lacking the ITAM-containing adapters DAP12 and FcRgamma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786293
retrieved
29 September 2017
Neutrophil-mediated oxidative burst and host defense are controlled by a Vav-PLCgamma2 signaling axis in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786293
retrieved
29 September 2017
Convergence of immunoreceptor and integrin signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786293
retrieved
29 September 2017
Distinct roles for Syk and ZAP-70 during early thymocyte development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786293
retrieved
29 September 2017
Neutrophils from p40phox-/- mice exhibit severe defects in NADPH oxidase regulation and oxidant-dependent bacterial killing.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786293
retrieved
29 September 2017
Enhanced Toll-like receptor responses in the absence of signaling adaptor DAP12.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786293
retrieved
29 September 2017
Src and Syk kinases: key regulators of phagocytic cell activation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786293
retrieved
29 September 2017
The molecular basis of fibronectin-mediated bacterial adherence to host cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786293
retrieved
29 September 2017
Phagocyte immunodeficiencies and their infections
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786293
retrieved
29 September 2017
The neutrophil as a cellular source of chemokines
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786293
retrieved
29 September 2017
Of man and mouse: leukocyte and endothelial adhesion molecule deficiencies.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786293
retrieved
29 September 2017
Integrin signalling in neutrophils and macrophages
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786293
retrieved
29 September 2017
Spontaneous skin ulceration and defective T cell function in CD18 null mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786293
retrieved
29 September 2017
The Syk protein tyrosine kinase is essential for Fcgamma receptor signaling in macrophages and neutrophils
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786293
retrieved
29 September 2017
Deficiency of Src family kinases p59/61hck and p58c-fgr results in defective adhesion-dependent neutrophil functions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786293
retrieved
29 September 2017
Subcellular localization and dynamics of Mac-1 (alpha m beta 2) in human neutrophils
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786293
retrieved
29 September 2017
Phagocyte C3-mediated attachment and internalization: flow cytometric studies using a fluorescence quenching technique.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786293
retrieved
3 June 2018
Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786293
retrieved
27 November 2018
Dectin-1 directs T helper cell differentiation by controlling noncanonical NF-kappaB activation through Raf-1 and Syk.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786293
retrieved
27 November 2018
JunB deficiency leads to a myeloproliferative disorder arising from hematopoietic stem cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786293
retrieved
27 November 2018
Three different neutrophil subsets exhibited in mice with different susceptibilities to infection by methicillin-resistant Staphylococcus aureus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786293
retrieved
27 November 2018
The Lyn tyrosine kinase negatively regulates neutrophil integrin signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786293
retrieved
27 November 2018
Role for plastin in host defense distinguishes integrin signaling from cell adhesion and spreading
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786293
retrieved
27 November 2018
Syk is required for integrin signaling in neutrophils
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786293
retrieved
27 November 2018
Long-term follow-up and outcome of 39 patients with chronic granulomatous disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786293
retrieved
27 November 2018
Conditional gene targeting in macrophages and granulocytes using LysMcre mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786293
retrieved
27 November 2018
Adhesion-dependent degranulation of neutrophils requires the Src family kinases Fgr and Hck
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786293
retrieved
27 November 2018
Localization of human neutrophil interleukin-8 (CXCL-8) to organelle(s) distinct from the classical granules and secretory vesicles
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19797524
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Mac-1 signaling via Src-family and Syk kinases results in elastase-dependent thrombohemorrhagic vasculopathy
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19797524
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Septic shock and acute lung injury in rabbits with peritonitis: failure of the neutrophil response to localized infection
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19797524
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Transgenic mice with hematopoietic and lymphoid specific expression of Cre
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19797524
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Changes in subcellular localization and surface expression of L-selectin, alkaline phosphatase, and Mac-1 in human neutrophils during stimulation with inflammatory mediators
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19797524
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Mice lacking neutrophil elastase reveal impaired host defense against gram negative bacterial sepsis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19797524
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1182/BLOOD-2009-05-220806
1 reference
stated in
PubMed
PubMed ID
19797524
retrieved
31 January 2017
PMCID
2786293
0 references
PubMed ID
19797524
1 reference
stated in
PubMed
PubMed ID
19797524
retrieved
31 January 2017
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