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Loss of presenilin 1 is associated with enhanced beta-catenin signaling and skin tumorigenesis
scientific journal article
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instance of
scholarly article
1 reference
stated in
PubMed
PubMed ID
11517342
retrieved
1 February 2017
title
Loss of presenilin 1 is associated with enhanced beta-catenin signaling and skin tumorigenesis
(English)
1 reference
stated in
PubMed
PubMed ID
11517342
retrieved
1 February 2017
main subject
Presenilin 1
1 reference
stated in
GOA release 2020-03-11
author name string
X. Xia
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
11517342
retrieved
1 February 2017
S. Qian
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
11517342
retrieved
1 February 2017
S. Soriano
series ordinal
3
1 reference
stated in
PubMed
PubMed ID
11517342
retrieved
1 February 2017
Y. Wu
series ordinal
4
1 reference
stated in
PubMed
PubMed ID
11517342
retrieved
1 February 2017
A. M. Fletcher
series ordinal
5
1 reference
stated in
PubMed
PubMed ID
11517342
retrieved
1 February 2017
X. J. Wang
series ordinal
6
1 reference
stated in
PubMed
PubMed ID
11517342
retrieved
1 February 2017
E. H. Koo
series ordinal
7
1 reference
stated in
PubMed
PubMed ID
11517342
retrieved
1 February 2017
X. Wu
series ordinal
8
1 reference
stated in
PubMed
PubMed ID
11517342
retrieved
1 February 2017
H. Zheng
series ordinal
9
1 reference
stated in
PubMed
PubMed ID
11517342
retrieved
1 February 2017
language of work or name
English
0 references
publication date
11 September 2001
1 reference
stated in
PubMed
PubMed ID
11517342
retrieved
1 February 2017
published in
Proceedings of the National Academy of Sciences of the United States of America
1 reference
stated in
PubMed
PubMed ID
11517342
retrieved
1 February 2017
volume
98
1 reference
stated in
PubMed
PubMed ID
11517342
retrieved
1 February 2017
page(s)
10863–10868
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stated in
PubMed
PubMed ID
11517342
retrieved
1 February 2017
issue
19
1 reference
stated in
PubMed
PubMed ID
11517342
retrieved
1 February 2017
cites work
Presenilin-mediated transmembrane cleavage is required for Notch signal transduction in Drosophila
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58565
retrieved
17 March 2017
AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58565
retrieved
17 March 2017
Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58565
retrieved
17 March 2017
Presenilin 1 facilitates the constitutive turnover of beta-catenin: differential activity of Alzheimer's disease-linked PS1 mutants in the beta-catenin-signaling pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58565
retrieved
17 March 2017
An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-catenin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58565
retrieved
17 March 2017
Presenilin is required for activity and nuclear access of Notch in Drosophila
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58565
retrieved
17 March 2017
A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58565
retrieved
17 March 2017
Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58565
retrieved
17 March 2017
A common human skin tumour is caused by activating mutations in beta-catenin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58565
retrieved
17 March 2017
Direct association of presenilin-1 with beta-catenin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58565
retrieved
17 March 2017
Identification of c-MYC as a target of the APC pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58565
retrieved
17 March 2017
The presenilin 1 protein is a component of a high molecular weight intracellular complex that contains beta-catenin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58565
retrieved
17 March 2017
Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58565
retrieved
17 March 2017
Presenilin 1 interaction in the brain with a novel member of the Armadillo family
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58565
retrieved
17 March 2017
Skeletal and CNS defects in Presenilin-1-deficient mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58565
retrieved
17 March 2017
Presenilin 1 is required for Notch1 and DII1 expression in the paraxial mesoderm
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58565
retrieved
17 March 2017
Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58565
retrieved
17 March 2017
Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58565
retrieved
17 March 2017
Functional interaction of beta-catenin with the transcription factor LEF-1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58565
retrieved
17 March 2017
Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58565
retrieved
17 March 2017
Cyclin D1 is a nuclear protein required for cell cycle progression in G1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58565
retrieved
17 March 2017
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58565
retrieved
17 March 2017
The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58565
retrieved
7 April 2017
De Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58565
retrieved
7 April 2017
Presenilin 1 negatively regulates beta-catenin/T cell factor/lymphoid enhancer factor-1 signaling independently of beta-amyloid precursor protein and notch processing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58565
retrieved
29 September 2017
Presenilin-1 binds cytoplasmic epithelial cadherin, inhibits cadherin/p120 association, and regulates stability and function of the cadherin/catenin adhesion complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58565
retrieved
29 September 2017
A screen for mutations that suppress the phenotype of Drosophila armadillo, the beta-catenin homolog.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58565
retrieved
29 September 2017
Beta-catenin, a novel prognostic marker for breast cancer: its roles in cyclin D1 expression and cancer progression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58565
retrieved
29 September 2017
Presenilin-1 forms complexes with the cadherin/catenin cell-cell adhesion system and is recruited to intercellular and synaptic contacts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58565
retrieved
29 September 2017
The cyclins and cyclin-dependent kinase inhibitors in hormonal regulation of proliferation and differentiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58565
retrieved
29 September 2017
Keratoacanthoma: a clinically distinct variant of well differentiated squamous cell carcinoma.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58565
retrieved
29 September 2017
The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58565
retrieved
29 September 2017
Destabilization of beta-catenin by mutations in presenilin-1 potentiates neuronal apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58565
retrieved
29 September 2017
Reduced skin tumor development in cyclin D1-deficient mice highlights the oncogenic ras pathway in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58565
retrieved
29 September 2017
Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58565
retrieved
29 September 2017
Mouse mammary tumor gene int-3: a member of the notch gene family transforms mammary epithelial cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58565
retrieved
29 September 2017
Presenilin affects arm/beta-catenin localization and function in Drosophila.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58565
retrieved
3 June 2018
Presenilin 1 controls gamma-secretase processing of amyloid precursor protein in pre-golgi compartments of hippocampal neurons
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58565
retrieved
3 June 2018
Neurogenic phenotypes and altered Notch processing in Drosophila Presenilin mutants.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58565
retrieved
3 June 2018
Beta-catenin: a key mediator of Wnt signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58565
retrieved
3 June 2018
Phosphorylation, subcellular localization, and membrane orientation of the Alzheimer's disease-associated presenilins.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58565
retrieved
3 June 2018
The nonconserved hydrophilic loop domain of presenilin (PS) is not required for PS endoproteolysis or enhanced abeta 42 production mediated by familial early onset Alzheimer's disease-linked PS variants.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58565
retrieved
27 November 2018
Mutant human presenilin 1 protects presenilin 1 null mouse against embryonic lethality and elevates Abeta1-42/43 expression.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58565
retrieved
27 November 2018
Interaction between Wingless and Notch signaling pathways mediated by dishevelled.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58565
retrieved
27 November 2018
Overexpression of cyclin D1 in mouse skin carcinogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58565
retrieved
27 November 2018
Regulation of Thy-1 gene expression in transgenic mice
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/11517342
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Early overexpression of cyclin D1 protein in mouse skin carcinogenesis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/11517342
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Cyclin D1 overexpression in mouse epidermis increases cyclin-dependent kinase activity and cell proliferation in vivo but does not affect skin tumor development
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/11517342
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1073/PNAS.191284198
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1889917
ADS bibcode
2001PNAS...9810863X
0 references
OpenCitations bibliographic resource ID
1889917
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1889917
PMCID
58565
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1889917
PubMed ID
11517342
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1889917
ResearchGate publication ID
235608287
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