(Q28601365)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25715355%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

title

Developing in vitro expanded CD45RA+ regulatory T cells as an adoptive cell therapy for Crohn's disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25715355%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

0 references

2

1 reference

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1 March 2020

Rimma Goldberg

4

1 reference

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1 March 2020

Nick Powell

10

1 reference

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1 March 2020

Behdad Afzali

16

1 reference

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1 March 2020

Maria Hernandez-Fuentes

18

1 reference

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1 March 2020

Graham M Lord

21

1 reference

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1 March 2020

author name string

James B Canavan

1

1 reference

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1 March 2020

Anna Vossenkämper

3

1 reference

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1 March 2020

Matthew J Elder

5

1 reference

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1 March 2020

Irit Shoval

6

1 reference

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1 March 2020

Ellen Marks

7

1 reference

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1 March 2020

Emilie Stolarczyk

8

1 reference

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1 March 2020

Jonathan W Lo

9

1 reference

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1 March 2020

Henrieta Fazekasova

11

1 reference

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1 March 2020

Peter M Irving

12

1 reference

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1 March 2020

Jeremy D Sanderson

13

1 reference

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1 March 2020

Jane K Howard

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25715355%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Simcha Yagel

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25715355%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Thomas T MacDonald

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25715355%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Nahum Y Shpigel

19

1 reference

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1 March 2020

Giovanna Lombardi

20

1 reference

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1 March 2020

language of work or name

English

0 references

publication date

24 February 2015

1 reference

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1 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25715355%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

volume

65

1 reference

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1 March 2020

issue

4

1 reference

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1 March 2020

page(s)

584-594

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25715355%20AND%20SRC:MED&resulttype=core&format=json

Retinoic acid and rapamycin differentially affect and synergistically promote the ex vivo expansion of natural human T regulatory cells

1 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4819603

Characterization of interleukin-17-producing regulatory T cells in inflamed intestinal mucosa from patients with inflammatory bowel diseases

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4819603

Differential responses of human regulatory T cells (Treg) and effector T cells to rapamycin

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4819603

Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4819603

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4819603

CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4819603

Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4819603

X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4819603

Clinical grade manufacturing of human alloantigen-reactive regulatory T cells for use in transplantation.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4819603

CD161 expression characterizes a subpopulation of human regulatory T cells that produces IL-17 in a STAT3-dependent manner.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4819603

Comparison of regulatory T cells in hemodialysis patients and healthy controls: implications for cell therapy in transplantation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4819603

Assessment of regulatory T-cell function in forthcoming clinical trials of cell therapy.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4819603

Differential effects of rapamycin and retinoic acid on expansion, stability and suppressive qualities of human CD4(+)CD25(+)FOXP3(+) T regulatory cell subpopulations

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4819603

The transcription factor T-bet regulates intestinal inflammation mediated by interleukin-7 receptor+ innate lymphoid cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4819603

Administration of CD4+CD25highCD127- regulatory T cells preserves β-cell function in type 1 diabetes in children

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4819603

Demethylation analysis of the FOXP3 locus shows quantitative defects of regulatory T cells in IPEX-like syndrome.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4819603

A rapid diagnostic test for human regulatory T-cell function to enable regulatory T-cell therapy.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4819603

Relative resistance of human CD4(+) memory T cells to suppression by CD4(+) CD25(+) regulatory T cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4819603

Human regulatory T cells with alloantigen specificity are more potent inhibitors of alloimmune skin graft damage than polyclonal regulatory T cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4819603

Massive ex vivo expansion of human natural regulatory T cells (T(regs)) with minimal loss of in vivo functional activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4819603

Stability of human rapamycin-expanded CD4+CD25+ T regulatory cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4819603

Ex vivo-expanded human regulatory T cells prevent the rejection of skin allografts in a humanized mouse model.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4819603

Epigenetic quantification of tumor-infiltrating T-lymphocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4819603

Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4819603

In vivo prevention of transplant arteriosclerosis by ex vivo-expanded human regulatory T cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4819603

Enhanced suppressive function of regulatory T cells from patients with immune-mediated diseases following successful ex vivo expansion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4819603

Decrease of Foxp3+ Treg cell number and acquisition of effector cell phenotype during lethal infection

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4819603

CD4+ regulatory T cells control TH17 responses in a Stat3-dependent manner.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4819603

Regulatory T cells: how do they suppress immune responses?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4819603

Regulatory T cells sequentially migrate from inflamed tissues to draining lymph nodes to suppress the alloimmune response.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4819603

Identification of IL-17-producing FOXP3+ regulatory T cells in humans.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4819603

Expansion of human regulatory T-cells from patients with type 1 diabetes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4819603

CCR4-dependent regulatory T cell function in inflammatory bowel disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4819603

Large-scale in vitro expansion of polyclonal human CD4(+)CD25high regulatory T cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4819603

Cutting edge: cure of colitis by CD4+CD25+ regulatory T cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4819603

CD4+ T cells that express high levels of CD45RB induce wasting disease when transferred into congenic severe combined immunodeficient mice. Disease development is prevented by cotransfer of purified CD4+ T cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4819603

Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4819603

Safety and efficacy of antigen-specific regulatory T-cell therapy for patients with refractory Crohn's disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4819603

Generation and large-scale expansion of human inducible regulatory T cells that suppress graft-versus-host disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4819603

Interleukin-12 converts Foxp3+ regulatory T cells to interferon-γ-producing Foxp3+ T cells that inhibit colitis.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4819603

Enterohemorrhagic Escherichia coli induce attaching and effacing lesions and hemorrhagic colitis in human and bovine intestinal xenograft models

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4819603

The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4819603

Cytotoxic-T-lymphocyte-associated antigen 4 blockade abrogates protection by regulatory T cells in a mouse model of microbially induced innate immune-driven colitis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4819603

Rapamycin promotes expansion of functional CD4+CD25+FOXP3+ regulatory T cells of both healthy subjects and type 1 diabetic patients

3 June 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-306919

Only the CD45RA+ subpopulation of CD4+CD25high T cells gives rise to homogeneous regulatory T-cell lines upon in vitro expansion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-306919

Peripheral and intestinal regulatory CD4+ CD25(high) T cells in inflammatory bowel disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-306919

Smad7 controls resistance of colitogenic T cells to regulatory T cell-mediated suppression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-306919

Post-transcriptional regulation of Smad7 in the gut of patients with inflammatory bowel disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-306919

Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-306919

Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-306919

Loss of FOXP3 expression in natural human CD4+CD25+ regulatory T cells upon repetitive in vitro stimulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-306919

Epigenetic reprogramming of the RORC locus during in vitro expansion is a distinctive feature of human memory but not naïve Treg.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-306919

DNA methylation controls Foxp3 gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-306919

In vivo differentiated cytokine-producing CD4(+) T cells express functional CCR7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-306919

Cutting edge: CD4+CD25+ regulatory T cells impaired for intestinal homing can prevent colitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-306919

Increase of regulatory T cells in ileal mucosa of untreated pediatric Crohn's disease patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-306919

Selective survival of naturally occurring human CD4+CD25+Foxp3+ regulatory T cells cultured with rapamycin

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4819603

CD4+CD25+ cell depletion from the normal CD4+ T cell pool prevents tolerance toward the intestinal flora and leads to chronic colitis in immunodeficient mice

27 November 2018

1 reference

12 December 2020

Species-specificity of T cell stimulating activities of IL 2 and BSF-1 (IL 4): comparison of normal and recombinant, mouse and human IL 2 and BSF-1 (IL 4)

1 reference

12 December 2020

Human intestine matures as nude mouse xenograft

1 reference

12 December 2020

Extrathymic T cell differentiation in the human intestine early in life

1 reference

12 December 2020

Only the CD62L+ subpopulation of CD4+CD25+ regulatory T cells protects from lethal acute GVHD

1 reference

12 December 2020

Characterization of FOXP3+CD4+ regulatory T cells in Crohn's disease

1 reference

12 December 2020

First-in-man clinical results of the treatment of patients with graft versus host disease with human ex vivo expanded CD4+CD25+CD127- T regulatory cells

1 reference

12 December 2020

Immunology. Regulatory T cells get their chance to shine

1 reference

12 December 2020

10.1136/GUTJNL-2014-306919

Identifiers

DOI

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25715355%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25715355%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25715355%20AND%20SRC:MED&resulttype=core&format=json