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Jagged1 (JAG1): Structure, expression, and disease associations
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
4673022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26548814%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
review article
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title
Jagged1 (JAG1): Structure, expression, and disease associations
(English)
1 reference
stated in
Europe PubMed Central
PMCID
4673022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26548814%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
part of the series
Gene Wiki Review Series
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author
Christopher M Grochowski
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
4673022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26548814%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
author name string
Kathleen M Loomes
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
4673022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26548814%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
Nancy B Spinner
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
4673022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26548814%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
language of work or name
English
0 references
publication date
6 November 2015
1 reference
stated in
Europe PubMed Central
PMCID
4673022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26548814%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
published in
Gene
1 reference
stated in
Europe PubMed Central
PMCID
4673022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26548814%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
volume
576
1 reference
stated in
Europe PubMed Central
PMCID
4673022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26548814%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
issue
1 Pt 3
1 reference
stated in
Europe PubMed Central
PMCID
4673022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26548814%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
page(s)
381-384
1 reference
stated in
Europe PubMed Central
PMCID
4673022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26548814%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
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Endothelial deletion of murine Jag1 leads to valve calcification and congenital heart defects associated with Alagille syndrome
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17 March 2017
Upregulated JAG1 enhances cell proliferation in adrenocortical carcinoma
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Cranial neural crest ablation of Jagged1 recapitulates the craniofacial phenotype of Alagille syndrome patients
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Jagged1 in the portal vein mesenchyme regulates intrahepatic bile duct development: insights into Alagille syndrome
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Jagged1 (JAG1) mutations in patients with tetralogy of Fallot or pulmonic stenosis
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Endothelial expression of the Notch ligand Jagged1 is required for vascular smooth muscle development
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17 March 2017
High-level JAG1 mRNA and protein predict poor outcome in breast cancer
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Gene alterations identified by expression profiling in tumor-associated endothelial cells from invasive ovarian carcinoma
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NOTCH2 mutations cause Alagille syndrome, a heterogeneous disorder of the notch signaling pathway
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Jagged1 (JAG1) mutations in Alagille syndrome: increasing the mutation detection rate
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17 March 2017
High-level coexpression of JAG1 and NOTCH1 is observed in human breast cancer and is associated with poor overall survival
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PubMed Central
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17 March 2017
Exon 6 of human Jagged-1 encodes an autonomously folding unit
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17 March 2017
A mouse model of Alagille syndrome: Notch2 as a genetic modifier of Jag1 haploinsufficiency
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17 March 2017
Defects in development of the kidney, heart and eye vasculature in mice homozygous for a hypomorphic Notch2 mutation
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17 March 2017
Defective intracellular transport and processing of JAG1 missense mutations in Alagille syndrome
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17 March 2017
Physical interaction of Delta1, Jagged1, and Jagged2 with Notch1 and Notch3 receptors
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17 March 2017
JAGGED1 expression in human embryos: correlation with the Alagille syndrome phenotype
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PubMed Central
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17 March 2017
The expression of Jagged1 in the developing mammalian heart correlates with cardiovascular disease in Alagille syndrome
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17 March 2017
Notch signaling: cell fate control and signal integration in development
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Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1
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Spectrum and frequency of jagged1 (JAG1) mutations in Alagille syndrome patients and their families
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Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1
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17 March 2017
Mutations in the human Jagged1 gene are responsible for Alagille syndrome
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PubMed Central
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17 March 2017
Jagged: a mammalian ligand that activates Notch1
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17 March 2017
TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms
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The canonical Notch signaling pathway: unfolding the activation mechanism
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Jagged1 heterozygosity in mice results in a congenital cholangiopathy which is reversed by concomitant deletion of one copy of Poglut1 (Rumi)
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29 September 2017
Renal involvement and the role of Notch signalling in Alagille syndrome
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4673022
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29 September 2017
NOTCH2 mutations in Alagille syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4673022
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29 September 2017
The notch signalling pathway in the development of the mouse placenta
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PubMed Central
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29 September 2017
The multifaceted role of Notch in cardiac development and disease
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PubMed Central
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29 September 2017
Character Changes Caused by Mutation of an Entire Region of a Chromosome in Drosophila
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29 September 2017
The role of Notch signaling in specification of podocyte and proximal tubules within the developing mouse kidney.
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29 September 2017
Consequences of JAG1 mutations
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PubMed Central
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29 September 2017
The Notch ligand Jagged1 is required for inner ear sensory development.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4673022
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29 September 2017
Familial Tetralogy of Fallot caused by mutation in the jagged1 gene
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4673022
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29 September 2017
Alagille syndrome
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4673022
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29 September 2017
Molecular cloning of Notch, a locus affecting neurogenesis in Drosophila melanogaster
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29 September 2017
Cell fate choices and the expression of Notch, Delta and Serrate homologues in the chick inner ear: parallels with Drosophila sense-organ development.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4673022
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3 June 2018
Bile duct proliferation in liver-specific Jag1 conditional knockout mice: effects of gene dosage.
1 reference
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reference URL
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27 November 2018
JAGGED1 gene expression during human embryogenesis elucidates the wide phenotypic spectrum of Alagille syndrome
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/26548814
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.GENE.2015.10.065
1 reference
stated in
Europe PubMed Central
PMCID
4673022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26548814%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
PMCID
4673022
1 reference
stated in
Europe PubMed Central
PMCID
4673022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26548814%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
PubMed ID
26548814
1 reference
stated in
Europe PubMed Central
PMCID
4673022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26548814%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
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