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Specific binding of the Akt-1 protein kinase to phosphatidylinositol 3,4,5-trisphosphate without subsequent activation
scientific journal article
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scholarly article
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PubMed
PubMed ID
8645147
retrieved
3 February 2017
title
Specific binding of the Akt-1 protein kinase to phosphatidylinositol 3,4,5-trisphosphate without subsequent activation
(English)
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PubMed
PubMed ID
8645147
retrieved
3 February 2017
author name string
S. R. James
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
8645147
retrieved
3 February 2017
C. P. Downes
series ordinal
2
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stated in
PubMed
PubMed ID
8645147
retrieved
3 February 2017
R. Gigg
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3
1 reference
stated in
PubMed
PubMed ID
8645147
retrieved
3 February 2017
S. J. Grove
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4
1 reference
stated in
PubMed
PubMed ID
8645147
retrieved
3 February 2017
A. B. Holmes
series ordinal
5
1 reference
stated in
PubMed
PubMed ID
8645147
retrieved
3 February 2017
D. R. Alessi
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6
1 reference
stated in
PubMed
PubMed ID
8645147
retrieved
3 February 2017
language of work or name
English
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publication date
1 May 1996
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PubMed
PubMed ID
8645147
retrieved
3 February 2017
published in
Biochemical Journal
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stated in
PubMed
PubMed ID
8645147
retrieved
3 February 2017
volume
315 ( Pt 3)
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stated in
PubMed
PubMed ID
8645147
retrieved
3 February 2017
page(s)
709–713
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stated in
PubMed
PubMed ID
8645147
retrieved
3 February 2017
cites work
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PubMed Central
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PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase
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Activation of PRK1 by phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. A comparison with protein kinase C isotypes
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Structure of the binding site for inositol phosphates in a PH domain
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Insulin stimulates the kinase activity of RAC-PK, a pleckstrin homology domain containing ser/thr kinase
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Molecular cloning and characterization of a new member of the RAC protein kinase family: association of the pleckstrin homology domain of three types of RAC protein kinase with protein kinase C subspecies and beta gamma subunits of G proteins
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Pathway of phosphatidylinositol(3,4,5)-trisphosphate synthesis in activated neutrophils
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AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas
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Isolation of transforming murine leukemia viruses from mice with a high incidence of spontaneous lymphoma
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Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane
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Activation of Raf as a result of recruitment to the plasma membrane
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7 April 2017
The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase
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Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction
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7 April 2017
A target for phosphoinositide 3-kinase: Akt/PKB.
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3 June 2018
Agonist-stimulated synthesis of phosphatidylinositol(3,4,5)-trisphosphate: a new intracellular signalling system?
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Interfacial hydrolysis of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate by turkey erythrocyte phospholipase C.
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3 June 2018
Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate.
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3 June 2018
The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: evidence that wortmannin blocks activation of the mitogen-activated prote
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3 June 2018
Wortmannin inhibits the effects of insulin and serum on the activities of glycogen synthase kinase-3 and mitogen-activated protein kinase
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PubMed Central
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3 June 2018
Activation of protein kinase C family members by the novel polyphosphoinositides PtdIns-3,4-P2 and PtdIns-3,4,5-P3.
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3 June 2018
Interleukin-2 triggers a novel phosphatidylinositol 3-kinase-dependent MEK activation pathway
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PubMed Central
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3 June 2018
PDGF stimulates an increase in GTP-Rac via activation of phosphoinositide 3-kinase
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PubMed Central
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3 June 2018
Specific and high-affinity binding of inositol phosphates to an isolated pleckstrin homology domain
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PubMed Central
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3 June 2018
Further studies on the structure of the glycogen-bound form of protein phosphatase-1 from rabbit skeletal muscle.
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PubMed Central
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3 June 2018
Molecular cloning and identification of a serine/threonine protein kinase of the second-messenger subfamily
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PubMed Central
reference URL
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3 June 2018
Molecular cloning and characterisation of a novel putative protein-serine kinase related to the cAMP-dependent and protein kinase C families
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PubMed Central
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3 June 2018
Activation of the zeta isozyme of protein kinase C by phosphatidylinositol 3,4,5-trisphosphate.
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217264
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A target for Pl(3) kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217264
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27 November 2018
Development regulation of the subcellular distribution and glycosylation of GLUT1 and GLUT4 glucose transporters during myogenesis of L6 muscle cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8645147
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Biospecific interaction analysis using surface plasmon resonance detection applied to kinetic, binding site and concentration analysis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8645147
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Phosphoinositide-specific phospholipase C-delta 1 binds with high affinity to phospholipid vesicles containing phosphatidylinositol 4,5-bisphosphate
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8645147
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Pleckstrin homology domain-mediated membrane association and activation of the beta-adrenergic receptor kinase requires coordinate interaction with G beta gamma subunits and lipid
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8645147
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Kinetic analysis of phospholipase C beta isoforms using phospholipid-detergent mixed micelles. Evidence for interfacial catalysis involving distinct micelle binding and catalytic steps
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8645147
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Intracellular signalling. PI 3-kinase puts GTP on the Rac
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8645147
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Phosphotyrosine residues in the nerve-growth-factor receptor (Trk-A). Their role in the activation of inositolphospholipid metabolism and protein kinase cascades in phaeochromocytoma (PC12) cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8645147
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Phosphatidylinositol (3,4,5)P3 interacts with SH2 domains and modulates PI 3-kinase association with tyrosine-phosphorylated proteins
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8645147
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1042/BJ3150709
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2074014
OpenCitations bibliographic resource ID
2074014
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2074014
PMCID
1217264
0 references
PubMed ID
8645147
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2074014
ResearchGate publication ID
14555711
0 references
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