(Q28618972)

3 February 2017

title

Critical role for lysines 21 and 22 in signal-induced, ubiquitin-mediated proteolysis of I kappa B-alpha (English)

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3 February 2017

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L. Baldi

1

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3 February 2017

K. Brown

series ordinal

2

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3 February 2017

G. Franzoso

series ordinal

3

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3 February 2017

U. Siebenlist

series ordinal

4

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3 February 2017

language of work or name

English

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publication date

5 January 1996

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Journal of Biological Chemistry

3 February 2017

published in

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3 February 2017

volume

271

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3 February 2017

issue

1

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3 February 2017

page(s)

376–379

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Function and activation of NF-kappa B in the immune system

3 February 2017

cites work

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https://api.crossref.org/works/10.1074%2FJBC.271.1.376

I kappa B interacts with the nuclear localization sequences of the subunits of NF-kappa B: a mechanism for cytoplasmic retention

21 January 2018

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I kappa B/MAD-3 masks the nuclear localization signal of NF-kappa B p65 and requires the transactivation domain to inhibit NF-kappa B p65 DNA binding

21 January 2018

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Intramolecular masking of the nuclear location signal and dimerization domain in the precursor for the p50 NF-kappa B subunit

21 January 2018

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Mutual regulation of the transcriptional activator NF-kappa B and its inhibitor, I kappa B-alpha

21 January 2018

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Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of I kappa B alpha: a mechanism for NF-kappa B activation

21 January 2018

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Rapid proteolysis of I kappa B-alpha is necessary for activation of transcription factor NF-kappa B

21 January 2018

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NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway

21 January 2018

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Autoregulation of the NF-kappa B transactivator RelA (p65) by multiple cytoplasmic inhibitors containing ankyrin motifs

21 January 2018

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Autoregulation of I kappa B alpha activity

21 January 2018

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Inducible phosphorylation of I kappa B alpha is not sufficient for its dissociation from NF-kappa B and is inhibited by protease inhibitors

21 January 2018

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Tumor necrosis factor alpha-induced phosphorylation of I kappa B alpha is a signal for its degradation but not dissociation from NF-kappa B

21 January 2018

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The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B

21 January 2018

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In vivo stimulation of I kappa B phosphorylation is not sufficient to activate NF-kappa B

21 January 2018

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Phosphorylation of I kappa B alpha precedes but is not sufficient for its dissociation from NF-kappa B

21 January 2018

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Activation of NF-kappa B requires proteolysis of the inhibitor I kappa B-alpha: signal-induced phosphorylation of I kappa B-alpha alone does not release active NF-kappa B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.1.376

Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation

21 January 2018

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Coupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activation

21 January 2018

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N- and C-terminal sequences control degradation of MAD3/I kappa B alpha in response to inducers of NF-kappa B activity

21 January 2018

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Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway

21 January 2018

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The ubiquitin-proteasome proteolytic pathway

21 January 2018

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Ornithine decarboxylase is degraded by the 26S proteasome without ubiquitination

21 January 2018

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Characterization of an immediate-early gene induced in adherent monocytes that encodes IκB-like activity

21 January 2018

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Highly inducible expression from vectors containing multiple GRE's in CHO cells overexpressing the glucocorticoid receptor

21 January 2018

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A novel mitogen-inducible gene product related to p50/p105-NF-kappa B participates in transactivation through a kappa B site

21 January 2018

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The candidate oncoprotein Bcl-3 is an antagonist of p50/NF-kappa B-mediated inhibition

21 January 2018

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The oncoprotein Bcl-3 directly transactivates through kappa B motifs via association with DNA-binding p50B homodimers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.1.376

Retinoic acid induction of major histocompatibility complex class I genes in NTera-2 embryonal carcinoma cells involves induction of NF-kappa B (p50-p65) and retinoic acid receptor beta-retinoid X receptor beta heterodimers

21 January 2018

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Direct association of pp40/I kappa B beta with rel/NF-kappa B transcription factors: role of ankyrin repeats in the inhibition of DNA binding activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.1.376

The PEST-like sequence of I kappa B alpha is responsible for inhibition of DNA binding but not for cytoplasmic retention of c-Rel or RelA homodimers

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.271.1.376

Structure of the NF-kappa B p50 homodimer bound to DNA

21 January 2018

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Structure of NF-kappa B p50 homodimer bound to a kappa B site

21 January 2018

1 reference

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cactus, a gene involved in dorsoventral pattern formation of Drosophila, is related to the I kappa B gene family of vertebrates

21 January 2018

1 reference

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Characterization of the Drosophila cactus locus and analysis of interactions between cactus and dorsal proteins

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.271.1.376

NF-kappa B: a lesson in family values

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.271.1.376

I kappa B-beta regulates the persistent response in a biphasic activation of NF-kappa B

21 January 2018

1 reference

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