(Q28646403)

English

Vascular endothelial growth factor (VEGF)-driven actin-based motility is mediated by VEGFR2 and requires concerted activation of stress-activated protein kinase 2 (SAPK2/p38) and geldanamycin-sensitive phosphorylation of focal adhesion kinase

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scholarly article

1 reference

3 February 2017

Vascular endothelial growth factor (VEGF)-driven actin-based motility is mediated by VEGFR2 and requires concerted activation of stress-activated protein kinase 2 (SAPK2/p38) and geldanamycin-sensitive phosphorylation of focal adhesion kinase (English)

1 reference

3 February 2017

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phosphorylation

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author name string

S. Rousseau

1

1 reference

3 February 2017

F. Houle

2

1 reference

3 February 2017

H. Kotanides

3

1 reference

3 February 2017

L. Witte

4

1 reference

3 February 2017

J. Waltenberger

5

1 reference

3 February 2017

J. Landry

6

1 reference

3 February 2017

J. Huot

7

1 reference

3 February 2017

language of work or name

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publication date

7 April 2000

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3 February 2017

Journal of Biological Chemistry

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3 February 2017

275

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3 February 2017

10661–10672

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3 February 2017

14

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3 February 2017

Vascular endothelial growth factor, a potent and selective angiogenic agent

1 reference

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21 January 2018

Indirect angiogenic cytokines upregulate VEGF and bFGF gene expression in vascular smooth muscle cells, whereas hypoxia upregulates VEGF expression only

1 reference

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21 January 2018

Hypoxia induces vascular endothelial growth factor in cultured human endothelial cells

1 reference

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21 January 2018

Endothelial receptor tyrosine kinases involved in angiogenesis.

1 reference

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21 January 2018

Characterization of novel vascular endothelial growth factor (VEGF) receptors on tumor cells that bind VEGF165 via its exon 7-encoded domain

1 reference

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21 January 2018

Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice

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21 January 2018

Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium

1 reference

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21 January 2018

Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice

1 reference

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21 January 2018

Tumor necrosis factor-alpha regulates expression of vascular endothelial growth factor receptor-2 and of its co-receptor neuropilin-1 in human vascular endothelial cells.

1 reference

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21 January 2018

Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor

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21 January 2018

Interaction of the Flt-1 tyrosine kinase receptor with the p85 subunit of phosphatidylinositol 3-kinase. Mapping of a novel site involved in binding

1 reference

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21 January 2018

The phosphorylated 1169-tyrosine containing region of flt-1 kinase (VEGFR-1) is a major binding site for PLCgamma

1 reference

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21 January 2018

Interactions of FLT-1 and KDR with phospholipase C gamma: identification of the phosphotyrosine binding sites

1 reference

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21 January 2018

Activation of mitogen-activated protein kinases by vascular endothelial growth factor and basic fibroblast growth factor in capillary endothelial cells is inhibited by the antiangiogenic factor 16-kDa N-terminal fragment of prolactin

1 reference

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21 January 2018

VEGF-A induces expression of eNOS and iNOS in endothelial cells via VEGF receptor-2 (KDR)

1 reference

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21 January 2018

The vascular endothelial growth factor receptor KDR activates multiple signal transduction pathways in porcine aortic endothelial cells

1 reference

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21 January 2018

Vascular endothelial growth factor stimulates tyrosine phosphorylation and recruitment to new focal adhesions of focal adhesion kinase and paxillin in endothelial cells

1 reference

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21 January 2018

The amino-terminal segment of the catalytic subunit of kidney Na,K-ATPase regulates the potassium deocclusion pathway of the reaction cycle

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21 January 2018

The role of the hsp90-based chaperone system in signal transduction by nuclear receptors and receptors signaling via MAP kinase

1 reference

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21 January 2018

In vivo function of Hsp90 is dependent on ATP binding and ATP hydrolysis

1 reference

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21 January 2018

The hsp90-based chaperone system: involvement in signal transduction from a variety of hormone and growth factor receptors

1 reference

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21 January 2018

Dynamic activation of endothelial nitric oxide synthase by Hsp90.

1 reference

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21 January 2018

Control of actin dynamics in cell motility

1 reference

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21 January 2018

Adhesion in cell migration

1 reference

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21 January 2018

Identification of p130Cas as a mediator of focal adhesion kinase-promoted cell migration

1 reference

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21 January 2018

Tyrosine kinase activity, cytoskeletal organization, and motility in human vascular endothelial cells

1 reference

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21 January 2018

Characterization of 45-kDa/54-kDa HSP27 kinase, a stress-sensitive kinase which may activate the phosphorylation-dependent protective function of mammalian 27-kDa heat-shock protein HSP27.

1 reference

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21 January 2018

Identification of mitogen-activated protein (MAP) kinase-activated protein kinase-3, a novel substrate of CSBP p38 MAP kinase

1 reference

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21 January 2018

Monoclonal antibodies targeting the VEGF receptor-2 (Flk1/KDR) as an anti-angiogenic therapeutic strategy

1 reference

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21 January 2018

Effects of experimental conditions on the production of interleukin-1 alpha and -1 beta by human endothelial cells cultured in vitro

1 reference

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21 January 2018

SAPK2/p38-dependent F-actin reorganization regulates early membrane blebbing during stress-induced apoptosis

1 reference

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21 January 2018

Modulation of cellular thermoresistance and actin filament stability accompanies phosphorylation-induced changes in the oligomeric structure of heat shock protein 27

1 reference

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21 January 2018

p38 MAP kinase activation by vascular endothelial growth factor mediates actin reorganization and cell migration in human endothelial cells.

1 reference

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21 January 2018

Placenta growth factor stimulates MAP kinase and mitogenicity but not phospholipase C-gamma and migration of endothelial cells expressing Flt 1

1 reference

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21 January 2018

SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1

1 reference

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21 January 2018

A synthetic inhibitor of the mitogen-activated protein kinase cascade

1 reference

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21 January 2018

Permissive role of nitric oxide in endothelin-induced migration of endothelial cells

1 reference

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21 January 2018

Vascular endothelial growth factor/vascular permeability factor augments nitric oxide release from quiescent rabbit and human vascular endothelium.

1 reference

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21 January 2018

The benzoquinone ansamycin geldanamycin stimulates proteolytic degradation of focal adhesion kinase

1 reference

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21 January 2018

The hsp90-binding antibiotic geldanamycin decreases Raf levels and epidermal growth factor signaling without disrupting formation of signaling complexes or reducing the specific enzymatic activity of Raf kinase

1 reference

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21 January 2018

The amino-terminal domain of heat shock protein 90 (hsp90) that binds geldanamycin is an ATP/ADP switch domain that regulates hsp90 conformation

1 reference

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21 January 2018

ADP-ribosylation of a small size GTP-binding protein in bovine neutrophils by the C3 exoenzyme of Clostridium botulinum and effect on the cell motility

1 reference

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21 January 2018

p38 Mitogen-activated protein kinase is a critical component of the redox-sensitive signaling pathways activated by angiotensin II. Role in vascular smooth muscle cell hypertrophy.

1 reference

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21 January 2018

A role for the p38 mitogen-activated protein kinase pathway in myocardial cell growth, sarcomeric organization, and cardiac-specific gene expression

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21 January 2018

Rho-stimulated contractility drives the formation of stress fibers and focal adhesions

1 reference

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21 January 2018

Focal adhesions, contractility, and signaling

1 reference

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21 January 2018

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1 reference

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21 January 2018

Inhibition of cell spreading by expression of the C-terminal domain of focal adhesion kinase (FAK) is rescued by coexpression of Src or catalytically inactive FAK: a role for paxillin tyrosine phosphorylation

1 reference

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21 January 2018

The Sch9 protein kinase regulates Hsp90 chaperone complex signal transduction activity in vivo

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21 January 2018

Inhibition of heat shock protein HSP90-pp60v-src heteroprotein complex formation by benzoquinone ansamycins: essential role for stress proteins in oncogenic transformation

1 reference

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21 January 2018

The Vascular Endothelial Growth Factor Receptor Flt-1 Mediates Biological Activities

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21 January 2018

Suramin is a Potent Inhibitor of Vascular Endothelial Growth Factor. A Contribution to the Molecular Basis of its Antiangiogenic Action

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21 January 2018

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