(Q28646948)

3 February 2017

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Europe PubMed Central

title

Calcium channel alpha2delta subunits: differential expression, function, and drug binding (English)

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3 February 2017

1

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author name string

Else Marais

series ordinal

2

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3 February 2017

Franz Hofmann

series ordinal

3

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3 February 2017

publication date

1 December 2003

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Journal of Bioenergetics and Biomembranes

3 February 2017

published in

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3 February 2017

volume

35

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3 February 2017

issue

6

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3 February 2017

page(s)

639–647

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Nomenclature of voltage-gated calcium channels

3 February 2017

cites work

1 reference

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Functional properties of a new voltage-dependent calcium channel alpha(2)delta auxiliary subunit gene (CACNA2D2)

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Subunits of purified calcium channels. Alpha 2 and delta are encoded by the same gene

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Seizure disorders in mutant mice: relevance to human epilepsies

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Cloning and deletion mutagenesis of the alpha2 delta calcium channel subunit from porcine cerebral cortex. Expression of a soluble form of the protein that retains [3H]gabapentin binding activity

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Subunit interaction sites in voltage-dependent Ca2+ channels: role in channel function.

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Primary structure of the gamma subunit of the DHP-sensitive calcium channel from skeletal muscle

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Inactivation of gating currents of L-type calcium channels. Specific role of the alpha 2 delta subunit

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Tissue-specific expression of splice variants of the mouse voltage-gated calcium channel alpha2/delta subunit

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Molecular cloning and characterization of the human voltage-gated calcium channel alpha(2)delta-4 subunit

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Dual function of the voltage-dependent Ca2+ channel alpha 2 delta subunit in current stimulation and subunit interaction.

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Subunit regulation of the neuronal alpha 1A Ca2+ channel expressed in Xenopus oocytes

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12 December 2020

Absence of modulation of the expressed calcium channel alpha1G subunit by alpha2delta subunits.

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Stable co-expression of calcium channel alpha 1, beta and alpha 2/delta subunits in a somatic cell line

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12 December 2020

Tissue-specific expression and gabapentin-binding properties of calcium channel alpha2delta subunit subtypes

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Allosteric modulation of [(3)H]gabapentin binding by ruthenium red

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12 December 2020

Isolation of the [3H]gabapentin-binding protein/alpha 2 delta Ca2+ channel subunit from porcine brain: development of a radioligand binding assay for alpha 2 delta subunits using [3H]leucine

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Dissection of functional domains of the voltage-dependent Ca2+ channel alpha2delta subunit.

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12 December 2020

An in vitro electrophysiological study on the effects of phenytoin, lamotrigine and gabapentin on striatal neurons

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Identification and functional characterization of a calcium channel gamma subunit

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12 December 2020

The effect of gabapentin on neuropathic pain

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12 December 2020

Ducky mouse phenotype of epilepsy and ataxia is associated with mutations in the Cacna2d2 gene and decreased calcium channel current in cerebellar Purkinje cells

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12 December 2020

Ca2+ current enhancement by alpha 2/delta and beta subunits in Xenopus oocytes: contribution of changes in channel gating and alpha 1 protein level

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12 December 2020

Structural characterization of the dihydropyridine-sensitive calcium channel alpha 2-subunit and the associated delta peptides

1 reference

12 December 2020

Extracellular interaction of the voltage-dependent Ca2+ channel alpha2delta and alpha1 subunits

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12 December 2020

Absence of the gamma subunit of the skeletal muscle dihydropyridine receptor increases L-type Ca2+ currents and alters channel inactivation properties

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12 December 2020

Inhibition of neuronal Ca(2+) influx by gabapentin and subsequent reduction of neurotransmitter release from rat neocortical slices

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Influence of L-type Ca channel alpha 2/delta-subunit on ionic and gating current in transiently transfected HEK 293 cells

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Gabapentin: pharmacokinetics, efficacy, and safety

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12 December 2020

The novel anticonvulsant drug, gabapentin (Neurontin), binds to the alpha2delta subunit of a calcium channel

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Neuronal distribution and functional characterization of the calcium channel alpha2delta-2 subunit

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The mouse stargazer gene encodes a neuronal Ca2+-channel gamma subunit.

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Structural requirement of the calcium-channel subunit alpha2delta for gabapentin binding

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12 December 2020

Effects of phenytoin, carbamazepine, and gabapentin on calcium channels in hippocampal granule cells from patients with temporal lobe epilepsy

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Stimulus-dependent modulation of [(3)H]norepinephrine release from rat neocortical slices by gabapentin and pregabalin

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Gabapentin inhibits calcium currents in isolated rat brain neurons

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Sequence and expression of mRNAs encoding the alpha 1 and alpha 2 subunits of a DHP-sensitive calcium channel

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A G-to-A single nucleotide polymorphism in the human alpha 2 delta 2 calcium channel subunit gene that maps at chromosome 3p21.3.

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12 December 2020

Gamma-aminobutyric acid type B receptors with specific heterodimer composition and postsynaptic actions in hippocampal neurons are targets of anticonvulsant gabapentin action.

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12 December 2020

Molecular diversity of the calcium channel alpha2delta subunit

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12 December 2020

Voltage-dependent Ca2+ channel alpha2delta auxiliary subunit: structure, function and regulation.

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12 December 2020

Cloning a calcium channel alpha2delta-3 subunit gene from a putative tumor suppressor gene region at chromosome 3p21.1 in conventional renal cell carcinoma

1 reference

12 December 2020

The ducky mutation in Cacna2d2 results in altered Purkinje cell morphology and is associated with the expression of a truncated alpha 2 delta-2 protein with abnormal function

1 reference

12 December 2020

Modulation of human neuronal alpha 1E-type calcium channel by alpha 2 delta-subunit.

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12 December 2020

Subunit regulation of the human brain alpha 1E calcium channel

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12 December 2020

The alpha 1 and alpha 2 polypeptides of the dihydropyridine-sensitive calcium channel differ in developmental expression and tissue distribution.

1 reference

12 December 2020

Calcium channel alpha(2)delta subunits-structure and Gabapentin binding

1 reference

12 December 2020

The alpha 2/delta subunit of voltage sensitive Ca2+ channels is a single transmembrane extracellular protein which is involved in regulated secretion

1 reference

12 December 2020

The effect of alpha2-delta and other accessory subunits on expression and properties of the calcium channel alpha1G.

1 reference

12 December 2020

Inhibition of neuronal Ca(2+) influx by gabapentin and pregabalin in the human neocortex

1 reference

12 December 2020