(Q2872459)

SAND-like domain superfamily

1 reference

Zinc finger, RING/FYVE/PHD-type

1 reference

Autoimmune regulator, AIRE

1 reference

Zinc finger, PHD-finger, protein family

1 reference

HSR domain, protein family

1 reference

Zinc finger, PHD-type, protein family

1 reference

SAND domain, protein family

1 reference

Zinc finger, PHD-type, conserved site, protein family

1 reference

RNA polymerase II transcription regulatory region sequence-specific DNA binding

1 reference

13 November 2019

1 reference

13 November 2019

2 references

1 reference

27 February 2018

The autoimmune regulator (AIRE) is a DNA-binding protein

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43918&geneProductId=UniProtKB:O43918

DNA-binding transcription activator activity, RNA polymerase II-specific

1 reference

8 April 2019

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43918

1 reference

27 February 2018

The autoimmune regulator PHD finger binds to non-methylated histone H3K4 to activate gene expression

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43918&geneProductId=UniProtKB:O43918

transcription coregulator activity

1 reference

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43918&geneProductId=UniProtKB:O43918

translation regulator activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43918

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43918

4 references

8 April 2019

The autoimmune regulator PHD finger binds to non-methylated histone H3K4 to activate gene expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43918

8 April 2019

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43918

8 April 2019

Aire's partners in the molecular control of immunological tolerance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43918

8 April 2019

DAXX is a new AIRE-interacting protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43918

identical protein binding

IPI

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43918

1 reference

8 April 2019

Structure and site-specific recognition of histone H3 by the PHD finger of human autoimmune regulator

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43918

DNA-binding transcription factor activity, RNA polymerase II-specific

RNA polymerase II transcription regulatory region sequence-specific DNA binding

ISM

NAS

3 references

8 April 2019

The autoimmune regulator PHD finger binds to non-methylated histone H3K4 to activate gene expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43918

8 April 2019

Structure and site-specific recognition of histone H3 by the PHD finger of human autoimmune regulator

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43918

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43918

intracellular anatomical structure

cell component

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43918&geneProductId=UniProtKB:O43918

6 references

8 April 2019

Positional cloning of the APECED gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43918

8 April 2019

An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43918

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43918

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43918

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43918

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43918

transcription, DNA-templated

biological process

1 reference

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43918&geneProductId=UniProtKB:O43918

negative thymic T cell selection

1 reference

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43918&geneProductId=UniProtKB:O43918

1 reference

8 April 2019

An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43918

regulation of translation

TAS

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43918

positive regulation of transcription by RNA polymerase II

2 references

27 February 2018

Subcellular localization of the autoimmune regulator protein. characterization of nuclear targeting and transcriptional activation domain

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43918&geneProductId=UniProtKB:O43918

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43918&geneProductId=UniProtKB:O43918

transcription by RNA polymerase II

1 reference

27 February 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43918&geneProductId=UniProtKB:O43918

central tolerance induction to self antigen

1 reference

27 February 2018

Dominant Mutations in the Autoimmune Regulator AIRE Are Associated with Common Organ-Specific Autoimmune Diseases

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43918&geneProductId=UniProtKB:O43918

positive regulation of transcription, DNA-templated

IMP

peripheral T cell tolerance induction

IMP

3 references

central tolerance induction to self antigen

regulation of transcription, DNA-templated

IMP

1 reference

8 April 2019

The autoimmune regulator PHD finger binds to non-methylated histone H3K4 to activate gene expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43918

positive regulation of transcription by RNA polymerase II

humoral immune response

3 references

3 references

8 April 2019

Subcellular localization of the autoimmune regulator protein. characterization of nuclear targeting and transcriptional activation domain

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43918

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43918

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43918

thymus epithelium morphogenesis

3 references

regulation of thymocyte migration

3 references

PBB GE AIRE 208090 s at fs.png
732 × 530; 12 KB

0 references

has part(s)

Zinc finger, PHD-type, conserved site

1 reference

Zinc finger, PHD-finger

1 reference

SAND domain

1 reference

HSR domain

1 reference

Zinc finger, PHD-type

1 reference

https://docs.openalex.org/download-snapshot/snapshot-data-format

Identifiers

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

0 references

Microsoft Academic ID

0 references

0 references

1 reference

26 January 2022

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016