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Aire's partners in the molecular control of immunological tolerance
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title
Aire's partners in the molecular control of immunological tolerance
(English)
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main subject
immunology
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based on heuristic
inferred from title
author
Matthieu Giraud
series ordinal
2
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Jakub Abramson
series ordinal
1
object named as
Jakub Abramson
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author name string
Christophe Benoist
series ordinal
3
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Diane Mathis
series ordinal
4
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language of work or name
English
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publication date
8 January 2010
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published in
Cell
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volume
140
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page(s)
123-35
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issue
1
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cites work
APECED-causing mutations in AIRE reveal the functional domains of the protein
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https://api.crossref.org/works/10.1016%2FJ.CELL.2009.12.030
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DNA-PK contributes to the phosphorylation of AIRE: importance in transcriptional activity
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https://api.crossref.org/works/10.1016%2FJ.CELL.2009.12.030
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Pre-mRNA processing reaches back to transcription and ahead to translation
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https://api.crossref.org/works/10.1016%2FJ.CELL.2009.12.030
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Control of inducible gene expression by signal-dependent transcriptional elongation
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SR proteins function in coupling RNAP II transcription to pre-mRNA splicing.
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Recognition of trimethylated histone H3 lysine 4 facilitates the recruitment of transcription postinitiation factors and pre-mRNA splicing
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FACT-mediated exchange of histone variant H2AX regulated by phosphorylation of H2AX and ADP-ribosylation of Spt16.
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https://api.crossref.org/works/10.1016%2FJ.CELL.2009.12.030
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Crosstalk between histone modifications during the DNA damage response.
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https://api.crossref.org/works/10.1016%2FJ.CELL.2009.12.030
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RNA polymerase II targets pre-mRNA splicing factors to transcription sites in vivo
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DNA topoisomerase IIalpha is required for RNA polymerase II transcription on chromatin templates
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The SAND domain structure defines a novel DNA-binding fold in transcriptional regulation
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https://api.crossref.org/works/10.1016%2FJ.CELL.2009.12.030
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The autoimmune regulator PHD finger binds to non-methylated histone H3K4 to activate gene expression
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Nuclear speckles: a model for nuclear organelles
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The splicing factor SC35 has an active role in transcriptional elongation
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The inner nuclear envelope as a transcription factor resting place
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Repair of ionizing radiation-induced DNA double-strand breaks by non-homologous end-joining
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https://api.crossref.org/works/10.1016%2FJ.CELL.2009.12.030
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Chromosomal clustering of genes controlled by the aire transcription factor
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https://api.crossref.org/works/10.1016%2FJ.CELL.2009.12.030
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Promiscuous gene expression patterns in single medullary thymic epithelial cells argue for a stochastic mechanism
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Transcriptional impact of Aire varies with cell type
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Ectopic expression of peripheral-tissue antigens in the thymic epithelium: probabilistic, monoallelic, misinitiated
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https://api.crossref.org/works/10.1016%2FJ.CELL.2009.12.030
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Aire employs a histone-binding module to mediate immunological tolerance, linking chromatin regulation with organ-specific autoimmunity.
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https://api.crossref.org/works/10.1016%2FJ.CELL.2009.12.030
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Subcellular expression of autoimmune regulator is organized in a spatiotemporal manner
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https://api.crossref.org/works/10.1016%2FJ.CELL.2009.12.030
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The autoimmune regulator protein has transcriptional transactivating properties and interacts with the common coactivator CREB-binding protein
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https://api.crossref.org/works/10.1016%2FJ.CELL.2009.12.030
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Medullary but not cortical thymic epithelial cells present soluble antigens to helper T cells
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https://api.crossref.org/works/10.1016%2FJ.CELL.2009.12.030
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Growth of epithelial cells in the thymic medulla is under the control of mature T cells
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https://api.crossref.org/works/10.1016%2FJ.CELL.2009.12.030
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Proliferative arrest and rapid turnover of thymic epithelial cells expressing Aire
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AIRE activated tissue specific genes have histone modifications associated with inactive chromatin
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Projection of an immunological self shadow within the thymus by the aire protein
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FACT facilitates transcription-dependent nucleosome alteration
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https://api.crossref.org/works/10.1016%2FJ.CELL.2009.12.030
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7 January 2021
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A topoisomerase IIbeta-mediated dsDNA break required for regulated transcription.
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Reciprocal binding of PARP-1 and histone H1 at promoters specifies transcriptional outcomes
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AIRE recruits P-TEFb for transcriptional elongation of target genes in medullary thymic epithelial cells
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https://api.crossref.org/works/10.1016%2FJ.CELL.2009.12.030
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Positive and negative selection of T cells
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https://api.crossref.org/works/10.1016%2FJ.CELL.2009.12.030
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A central role for central tolerance
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https://api.crossref.org/works/10.1016%2FJ.CELL.2009.12.030
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Aire
1 reference
stated in
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reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2009.12.030
retrieved
7 January 2021
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Mechanisms of an autoimmunity syndrome in mice caused by a dominant mutation in Aire
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https://api.crossref.org/works/10.1016%2FJ.CELL.2009.12.030
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Numerical analysis of etoposide induced DNA breaks
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https://api.crossref.org/works/10.1016%2FJ.CELL.2009.12.030
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Identifiers
DOI
10.1016/J.CELL.2009.12.030
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PubMed ID
20085707
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ResearchGate publication ID
41087811
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