(Q28730115)

3

0 references

David Hinrichs

4

0 references

Keith Wegmann

5

0 references

Gary L Zhang

6

0 references

Mark Hall

7

0 references

James T Rosenbaum

Creative Commons Attribution 4.0 International

8

0 references

language of work or name

English

0 references

publication date

2012

0 references

published in

PLOS One

0 references

volume

7

0 references

issue

5

0 references

page(s)

e36589

0 references

copyright license

start time

4 May 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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1 reference

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GOLPH3 modulates mTOR signalling and rapamycin sensitivity in cancer

17 March 2017

1 reference

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Differential responses of human regulatory T cells (Treg) and effector T cells to rapamycin

17 March 2017

1 reference

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mTOR regulates memory CD8 T-cell differentiation

17 March 2017

1 reference

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TOR signaling in growth and metabolism

17 March 2017

1 reference

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Regulation of immune cells by local-tissue oxygen tension: HIF1 alpha and adenosine receptors

17 March 2017

1 reference

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Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

17 March 2017

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Rapamycin (AY-22,989), a new antifungal antibiotic. I. Taxonomy of the producing streptomycete and isolation of the active principle

17 March 2017

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Autophagy-dependent anticancer immune responses induced by chemotherapeutic agents in mice

17 March 2017

1 reference

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Termination of autophagy and reformation of lysosomes regulated by mTOR

7 April 2017

1 reference

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Activation of OX40 prolongs and exacerbates autoimmune experimental uveitis

7 April 2017

1 reference

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mTOR signaling and metabolic regulation of T cells: new potential therapeutic targets in autoimmune diseases.

3 June 2018

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Cytokines in autoimmune uveitis

3 June 2018

1 reference

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Characterization of the metabolic phenotype of rapamycin-treated CD8+ T cells with augmented ability to generate long-lasting memory cells

3 June 2018

1 reference

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Amplification of the angiogenic signal through the activation of the TSC/mTOR/HIF axis by the KSHV vGPCR in Kaposi's sarcoma

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3344911

Sirolimus enhances the magnitude and quality of viral-specific CD8+ T-cell responses to vaccinia virus vaccination in rhesus macaques

3 June 2018

1 reference

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Regulatory T cells require mammalian target of rapamycin signaling to maintain both homeostasis and alloantigen-driven proliferation in lymphocyte-replete mice

3 June 2018

1 reference

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An oscillatory switch in mTOR kinase activity sets regulatory T cell responsiveness.

3 June 2018

1 reference

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The mammalian target of rapamycin: linking T cell differentiation, function, and metabolism

3 June 2018

1 reference

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mTOR signalling and metabolic regulation of T cell differentiation

3 June 2018

1 reference

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Cutting edge: Rapamycin augments pathogen-specific but not graft-reactive CD8+ T cell responses

3 June 2018

1 reference

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A subretinal matrigel rat choroidal neovascularization (CNV) model and inhibition of CNV and associated inflammation and fibrosis by VEGF trap

3 June 2018

1 reference

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The role of mTOR in memory CD8 T-cell differentiation

3 June 2018

1 reference

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Müller cell-derived VEGF is essential for diabetes-induced retinal inflammation and vascular leakage

3 June 2018

1 reference

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Membrane-bound Fas ligand only is essential for Fas-induced apoptosis

3 June 2018

1 reference

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mTOR: taking cues from the immune microenvironment

3 June 2018

1 reference

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Enhancing CD8 T-cell memory by modulating fatty acid metabolism

3 June 2018

1 reference

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Immunoregulatory functions of mTOR inhibition.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3344911

Sirolimus reduces the incidence and progression of UVB-induced skin cancer in SKH mice even with co-administration of cyclosporine A.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3344911

Repertoire analysis and new pathogenic epitopes of IRBP in C57BL/6 (H-2b) and B10.RIII (H-2r) mice

3 June 2018

1 reference

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New perspectives on effector mechanisms in uveitis

3 June 2018

1 reference

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Cytochrome P450 3A polymorphisms and immunosuppressive drugs: an update

3 June 2018

1 reference

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Pneumonitis associated with sirolimus: clinical characteristics, risk factors and outcome--a single-centre experience and review of the literature.

3 June 2018

1 reference

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Hypoxia-inducible factor 1alpha is regulated by the mammalian target of rapamycin (mTOR) via an mTOR signaling motif

3 June 2018

1 reference

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The role of HIF-1alpha in myeloid cell inflammation

3 June 2018

1 reference

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mTOR--beyond transplantation

3 June 2018

1 reference

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Sirolimus-associated pulmonary toxicity

3 June 2018

1 reference

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Sirolimus-induced pneumonitis: three cases and a review of the literature

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3344911

Negative Regulation of Interleukin-12 Production by a Rapamycin-Sensitive Signaling Pathway: A Brief Communication

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3344911

Activation-induced cell death in T cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3344911

Transplant immunosuppressant agents and their role in autoimmune rheumatic diseases

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3344911

Drug-eluting stents in vascular intervention

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3344911

BCR/ABL induces expression of vascular endothelial growth factor and its transcriptional activator, hypoxia inducible factor-1alpha, through a pathway involving phosphoinositide 3-kinase and the mammalian target of rapamycin.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3344911

Activation-induced cell death

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3344911

Lessons from bcl-2 transgenic mice for immunology, cancer biology and cell death research.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3344911

Experimental autoimmune uveitis and its relationship to clinical ocular inflammatory disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3344911

Fas ligand mediates activation-induced cell death in human T lymphocytes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3344911

Cyclosporin A inhibits activation-induced cell death in T-cell hybridomas and thymocytes.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3344911

Rapamycin pre-treatment protects against apoptosis

3 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0036589

Pharmacogenetics of tacrolimus and sirolimus in renal transplant patients: from retrospective analyses to prospective studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0036589

Anemia after late introduction of sirolimus may correlate with biochemical evidence of a chronic inflammatory state

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0036589

Immunology: A metabolic switch to memory.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0036589

Autophagy enhances the efficacy of BCG vaccine by increasing peptide presentation in mouse dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0036589

A new model of autoimmune disease. Experimental autoimmune uveoretinitis induced in mice with two different retinal antigens

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3344911

Rapamycin selectively blocks interleukin-2-induced proliferating cell nuclear antigen gene expression in T lymphocyte. Evidence for inhibition of CREB/ATF binding activities

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22574188

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Intracellular network of phosphatidylinositol 3-kinase, mammalian target of the rapamycin/70 kDa ribosomal S6 kinase 1, and mitogen-activated protein kinases pathways for regulating mycobacteria-induced IL-23 expression in human macrophages

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22574188