(Q28755947)

English

Single cell analysis reveals regulated hierarchical T cell antigen receptor signaling thresholds and intraclonal heterogeneity for individual cytokine responses of CD4+ T cells

scientific article (publication date: 29 August 1997)

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scholarly article

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Single cell analysis reveals regulated hierarchical T cell antigen receptor signaling thresholds and intraclonal heterogeneity for individual cytokine responses of CD4+ T cells (English)

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author name string

Y Itoh

1

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R N Germain

2

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publication date

29 August 1997

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Journal of Experimental Medicine

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186

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5

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757-66

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The role of the CD28 receptor during T cell responses to antigen

2 references

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T cell receptor antagonist peptides induce positive selection

1 reference

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Interleukin 2 production, not the pattern of early T-cell antigen receptor-dependent tyrosine phosphorylation, controls anergy induction by both agonists and partial agonists

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Models of T cell anergy: is there a common molecular mechanism?

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Peptide-major histocompatibility complex class II complexes with mixed agonist/antagonist properties provide evidence for ligand-related differences in T cell receptor-dependent intracellular signaling

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Evidence for protein tyrosine kinase involvement in ligand-induced TCR/CD3 internalization and surface redistribution

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1 reference

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Zeta phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists

1 reference

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Serial triggering of many T-cell receptors by a few peptide-MHC complexes

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Single cell analysis of cytokine gene coexpression during CD4+ T-cell phenotype development.

1 reference

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Extent of T cell receptor ligation can determine the functional differentiation of naive CD4+ T cells

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Identifiers

10.1084/JEM.186.5.757

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