(Q28771722)

14 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23093599%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

title

Targeting the DNA-binding activity of the human ERG transcription factor using new heterocyclic dithiophene diamidines (English)

2 references

14 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23093599%20AND%20SRC:MED&resulttype=core&format=json

ETS transcription factor ERG

16 February 2020

main subject

1 reference

RNA polymerase II cis-regulatory region sequence-specific DNA binding

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Xavier Dezitter

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23093599%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Mohamed A. Ismail

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23093599%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Abdelbasset A. Farahat

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23093599%20AND%20SRC:MED&resulttype=core&format=json

Martine Duterque-Coquillaud

16 February 2020

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23093599%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

author name string

Raja Nhili

1

2 references

14 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23093599%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Paul Peixoto

2

2 references

14 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23093599%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Sabine Depauw

3

2 references

14 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23093599%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Sébastien Flajollet

4

2 references

14 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23093599%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Arvind Kumar

8

2 references

14 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23093599%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Marie-Hélène David-Cordonnier

14

2 references

14 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23093599%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Manoj M Munde

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23093599%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Chad E Stephens

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23093599%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

W David Wilson

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23093599%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

David W Boykin

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23093599%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

language of work or name

English

0 references

publication date

23 October 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23093599%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

published in

Nucleic Acids Research

2 references

14 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23093599%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

volume

41

2 references

14 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23093599%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

issue

1

2 references

14 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23093599%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

page(s)

125-138

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23093599%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution-NonCommercial 3.0 Unported

16 February 2020

copyright license

start time

4 October 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3592449/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Comprehensive study in the inhibitory effect of berberine on gene transcription, including TATA box

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592449

YK-4-279 inhibits ERG and ETV1 mediated prostate cancer cell invasion

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592449

Ecteinascidin 743 interferes with the activity of EWS-FLI1 in Ewing sarcoma cells

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592449

Role of the TMPRSS2-ERG gene fusion in prostate cancer

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592449

Transcription factor Erg regulates angiogenesis and endothelial apoptosis through VE-cadherin

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592449

ELF4 is fused to ERG in a case of acute myeloid leukemia with a t(X;21)(q25–26;q22)

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592449

Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer.

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592449

enoLOGOS: a versatile web tool for energy normalized sequence logos

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592449

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592449

Inhibition of RNA polymerase II transcription in human cells by synthetic DNA-binding ligands

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592449

Erg proteins, transcription factors of the Ets family, form homo, heterodimers and ternary complexes via two distinct domains

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592449

New human erg isoforms generated by alternative splicing are transcriptional activators

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592449

A second Ewing's sarcoma translocation, t(21;22), fuses the EWS gene to another ETS-family transcription factor, ERG

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592449

Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592449

Modulation of NF-κB-dependent gene transcription using programmable DNA minor groove binders

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592449

Targeting a DNA binding motif of the EVI1 protein by a pyrrole-imidazole polyamide

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592449

Novel peptide binds EWS-FLI1 and reduces the oncogenic potential in Ewing tumors

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592449

Abnormal expression of the ERG transcription factor in prostate cancer cells activates osteopontin

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592449

Identification of an inhibitor of the EWS-FLI1 oncogenic transcription factor by high-throughput screening.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592449

Water-mediated binding of agents that target the DNA minor groove

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592449

Histone deacetylase inhibitors, valproic acid and trichostatin-A induce apoptosis and affect acetylation status of p53 in ERG-positive prostate cancer cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592449

Dicationic phenyl-2,2'-bichalcophenes and analogues as antiprotozoal agents

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592449

Genome-wide analysis of ETS-family DNA-binding in vitro and in vivo

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592449

A complex task? Direct modulation of transcription factors with small molecules

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592449

Novel diamidino-substituted derivatives of phenyl benzothiazolyl and dibenzothiazolyl furans and thiophenes: synthesis, antiproliferative and DNA binding properties.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592449

Detection of FUS-ERG chimeric transcript in two cases of acute myeloid leukemia with t(16;21)(p11.2;q22) with unusual characteristics

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592449

A small molecule blocking oncogenic protein EWS-FLI1 interaction with RNA helicase A inhibits growth of Ewing's sarcoma

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592449

Minor groove binding compounds that jump a gc base pair and bind to adjacent AT base pair sites

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592449

Defining the molecular action of HDAC inhibitors and synergism with androgen deprivation in ERG-positive prostate cancer

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592449

Direct inhibition of the DNA-binding activity of POU transcription factors Pit-1 and Brn-3 by selective binding of a phenyl-furan-benzimidazole dication

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592449

Genome-wide analyses reveal properties of redundant and specific promoter occupancy within the ETS gene family

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592449

Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening, induces antitumor activity

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592449

Frequency of the TMPRSS2:ERG gene fusion is increased in moderate to poorly differentiated prostate cancers

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592449

Programmable oligomers for minor groove DNA recognition

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592449

Stromelysin-1 expression is activated in vivo by Ets-1 through palindromic head-to-head Ets binding sites present in the promoter.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592449

Molecular biology of the Ets family of transcription factors

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592449

Transcription factors as targets for cancer therapy

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592449

Recognition of ATGA sequences by the unfused aromatic dication DB293 forming stacked dimers in the DNA minor groove

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592449

Interaction of murine ets-1 with GGA-binding sites establishes the ETS domain as a new DNA-binding motif

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592449

Dual effect of echinomycin on hypoxia-inducible factor-1 activity under normoxic and hypoxic conditions

3 June 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKS971

TMPRSS2:ERG gene fusion associated with lethal prostate cancer in a watchful waiting cohort.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKS971

ERG is a megakaryocytic oncogene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKS971

High expression of the ETS transcription factor ERG predicts adverse outcome in acute T-lymphoblastic leukemia in adults.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKS971

ERG expression is an independent prognostic factor and allows refined risk stratification in cytogenetically normal acute myeloid leukemia: a comprehensive analysis of ERG, MN1, and BAALC transcript levels using oligonucleotide microarrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKS971

Synthesis and biological evaluation of N-substituted benzo[c]phenanthrolines and benzo[c]phenanthrolinones as antiproliferative agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKS971

DNA binding specificity studies of four ETS proteins support an indirect read-out mechanism of protein-DNA recognition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKS971

The transcription factor Erg regulates expression of histone deacetylase 6 and multiple pathways involved in endothelial cell migration and angiogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKS971

Linear and circular dichroism of drug-nucleic acid complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKS971

The Ewing Family of Tumors -- A Subgroup of Small-Round-Cell Tumors Defined by Specific Chimeric Transcripts

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKS971

An efficient synthesis of 5,5′-diaryl-2,2′-bichalcophenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKS971

The E3 ubiquitin ligase complex component COP1 regulates PEA3 group member stability and transcriptional activity

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/23093599

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The ETS-domain: a new DNA-binding motif that recognizes a purine-rich core DNA sequence

1 reference

https://pubmed.ncbi.nlm.nih.gov/23093599

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

2 references

14 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23093599%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23093599%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

2 references

14 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23093599%20AND%20SRC:MED&resulttype=core&format=json