(Q28817472)

English

Discovery and Mechanistic Characterization of Selective Inhibitors of H2S-producing Enzyme: 3-Mercaptopyruvate Sulfurtransferase (3MST) Targeting Active-site Cysteine Persulfide

scientific article (publication date: 12 January 2017)

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scholarly article

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Discovery and Mechanistic Characterization of Selective Inhibitors of H2S-producing Enzyme: 3-Mercaptopyruvate Sulfurtransferase (3MST) Targeting Active-site Cysteine Persulfide (English)

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Mercaptopyruvate sulfurtransferase

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GOA release 2020-03-11

8

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28079151%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

9

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9 June 2020

13

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Europe PubMed Central

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9 June 2020

14

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9 June 2020

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Kenjiro Hanaoka

1

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9 June 2020

Kiyoshi Sasakura

2

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9 June 2020

Yusuke Suwanai

3

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9 June 2020

Sachiko Toma-Fukai

4

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9 June 2020

Kazuhito Shimamoto

5

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9 June 2020

Yoko Takano

6

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9 June 2020

Norihiro Shibuya

7

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9 June 2020

Tasuku Ueno

10

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9 June 2020

Yuki Ogasawara

11

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9 June 2020

Yukihiro Tsuchiya

12

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9 June 2020

Chao Wang

15

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9 June 2020

Masanobu Uchiyama

16

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9 June 2020

Hirotatsu Kojima

17

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9 June 2020

Takayoshi Okabe

18

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Europe PubMed Central

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9 June 2020

Yasuteru Urano

19

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Europe PubMed Central

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9 June 2020

Toshiyuki Shimizu

20

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9 June 2020

Tetsuo Nagano

21

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9 June 2020

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publication date

12 January 2017

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Scientific Reports

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9 June 2020

7

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Europe PubMed Central

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9 June 2020

40227

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9 June 2020

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Creative Commons Attribution 4.0 International

12 January 2017

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April 2022 Public Data File from Crossref

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Biogenesis of reactive sulfur species for signaling by hydrogen sulfide oxidation pathways

1 reference

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16 March 2017

Antioxidant enzyme, 3-mercaptopyruvate sulfurtransferase-knockout mice exhibit increased anxiety-like behaviors: a model for human mercaptolactate-cysteine disulfiduria

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16 March 2017

Structure and Kinetic Analysis of H2S Production by Human Mercaptopyruvate Sulfurtransferase

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16 March 2017

Structure-activity characterization of sulfide:quinone oxidoreductase variants

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REFMAC5 for the refinement of macromolecular crystal structures

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Crystal structure of sulfide:quinone oxidoreductase from Acidithiobacillus ferrooxidans: insights into sulfidotrophic respiration and detoxification

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16 March 2017

H2S as a physiologic vasorelaxant: hypertension in mice with deletion of cystathionine gamma-lyase

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16 March 2017

3-Mercaptopyruvate sulfurtransferase produces hydrogen sulfide and bound sulfane sulfur in the brain

1 reference

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16 March 2017

Refinement of macromolecular structures by the maximum-likelihood method

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16 March 2017

The "rhodanese" fold and catalytic mechanism of 3-mercaptopyruvate sulfurtransferases: crystal structure of SseA from Escherichia coli

1 reference

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16 March 2017

The crystal structure of Leishmania major 3-mercaptopyruvate sulfurtransferase. A three-domain architecture with a serine protease-like triad at the active site

1 reference

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16 March 2017

Specific interaction of lipoate at the active site of rhodanese

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16 March 2017

The crystal structure of a sulfurtransferase from Azotobacter vinelandii highlights the evolutionary relationship between the rhodanese and phosphatase enzyme families

1 reference

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16 March 2017

Processing of X-ray diffraction data collected in oscillation mode

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7 April 2017

Biosynthesis and Reactivity of Cysteine Persulfides in Signaling

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3 June 2018

Identification of H2S3 and H2S produced by 3-mercaptopyruvate sulfurtransferase in the brain

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3 June 2018

Reaction of Hydrogen Sulfide with Disulfide and Sulfenic Acid to Form the Strongly Nucleophilic Persulfide.

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3 June 2018

Reactive cysteine persulfides and S-polythiolation regulate oxidative stress and redox signaling

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3 June 2018

Polysulfides link H2S to protein thiol oxidation.

1 reference

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3 June 2018

Learning from our mistakes: the 'unknown knowns' in fragment screening

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3 June 2018

Selectivity of commonly used pharmacological inhibitors for cystathionine β synthase (CBS) and cystathionine γ lyase (CSE).

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3 June 2018

H₂S signalling through protein sulfhydration and beyond

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3 June 2018

Emerging role of hydrogen sulfide in health and disease: critical appraisal of biomarkers and pharmacological tools

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3 June 2018

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3 June 2018

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3 June 2018

Vascular endothelium expresses 3-mercaptopyruvate sulfurtransferase and produces hydrogen sulfide.

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3 June 2018

Models of S/pi interactions in protein structures: comparison of the H2S benzene complex with PDB data.

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3 June 2018

Menadione effect on l-cysteine desulfuration in U373 cells.

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3 June 2018

L-cysteine inhibits insulin release from the pancreatic beta-cell: possible involvement of metabolic production of hydrogen sulfide, a novel gasotransmitter

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3 June 2018

The rhodanese/Cdc25 phosphatase superfamily. Sequence-structure-function relations

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3 June 2018

Role of amino acid residues in the active site of rat liver mercaptopyruvate sulfurtransferase. CDNA cloning, overexpression, and site-directed mutagenesis

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3 June 2018

3-Mercaptopyruvate sulfurtransferase: rapid equilibrium-ordered mechanism with cyanide as the acceptor substrate.

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3 June 2018

The covalent and tertiary structure of bovine liver rhodanese

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3 June 2018

H2S: a universal defense against antibiotics in bacteria

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21 January 2018

Involvement of reactive persulfides in biological bismethylmercury sulfide formation

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21 January 2018

Polysulfides are possible H2S-derived signaling molecules in rat brain.

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21 January 2018

Affinity labeling of a catalytic site, cysteine(247), in rat mercaptopyruvate sulfurtransferase by chloropyruvate as an analog of a substrate

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21 January 2018

On the importance of anion-π interactions in the mechanism of sulfide:quinone oxidoreductase

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21 January 2018

The expression and activity of cystathionine-γ-lyase and 3-mercaptopyruvate sulfurtransferase in human neoplastic cell lines.

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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26 November 2018

Hydrogen sulfide is a novel mediator of lipopolysaccharide-induced inflammation in the mouse

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26 November 2018

The activity of 3-mercaptopyruvate sulfurtransferase in erythrocytes from patients with polycythemia vera

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of a highly selective fluorescence probe for hydrogen sulfide

1 reference

https://pubmed.ncbi.nlm.nih.gov/28079151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of three alpha-keto acids on 3-mercaptopyruvate sulfurtransferase activity

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specificity studies of 3-Mercaptopyruvate sulfurtransferase

1 reference

https://pubmed.ncbi.nlm.nih.gov/28079151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SREP40227

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28079151%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28079151%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28079151%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

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