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TGN1412: From Discovery to Disaster
scientific article (publication date: 2010)
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title
TGN1412: From Discovery to Disaster
(English)
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pmc&retmode=json&id=2964774
retrieved
20 March 2017
author name string
Attarwala H
series ordinal
1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pmc&retmode=json&id=2964774
retrieved
20 March 2017
publication date
2010
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pmc&retmode=json&id=2964774
retrieved
20 March 2017
published in
Journal of Young Pharmacists
1 reference
stated in
PubMed
volume
2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pmc&retmode=json&id=2964774
retrieved
20 March 2017
issue
3
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pmc&retmode=json&id=2964774
retrieved
20 March 2017
page(s)
332-336
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pmc&retmode=json&id=2964774
retrieved
20 March 2017
cites work
Safety of biologics, lessons learnt from TGN1412
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964774
retrieved
20 March 2017
Topological requirements and signaling properties of T cell-activating, anti-CD28 antibody superagonists
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964774
retrieved
20 March 2017
Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964774
retrieved
7 April 2017
The TeGenero incident and the Duff Report conclusions: a series of unfortunate events or an avoidable event?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964774
retrieved
3 June 2018
CD28 superagonists: what makes the difference in humans?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964774
retrieved
3 June 2018
Preparing for first-in-man studies: the challenges for translational immunology post-TGN1412.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964774
retrieved
3 June 2018
Manipulation of regulatory T-cell number and function with CD28-specific monoclonal antibodies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964774
retrieved
3 June 2018
Further lessons from the TGN1412 tragedy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964774
retrieved
3 June 2018
Mitochondrial injury. Lessons from the fialuridine trial
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964774
retrieved
3 June 2018
Fialuridine accumulates in DNA of dogs, monkeys, and rats following long-term oral administration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964774
retrieved
3 June 2018
Hepatic failure and lactic acidosis due to fialuridine (FIAU), an investigational nucleoside analogue for chronic hepatitis B.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964774
retrieved
3 June 2018
Ethical flaws in the TeGenero trial.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964774
retrieved
26 November 2018
Lessons from TGN1412.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964774
retrieved
26 November 2018
TGN1412: scrutinizing preclinical trials of antibody-based medicines.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964774
retrieved
26 November 2018
Allergy test might have avoided drug-trial disaster
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964774
retrieved
26 November 2018
Expansion of functional endogenous antigen-specific CD4+CD25+ regulatory T cells from nonobese diabetic mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964774
retrieved
26 November 2018
Phase I antibody risks, trial safety examined
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21042496
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Depletion of mitochondrial DNA, destruction of mitochondria, and accumulation of lipid droplets result from fialuridine treatment in woodchucks (Marmota monax)
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21042496
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Mitochondrial toxicity--new adverse drug effects
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21042496
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Review of Sofia Gruskin, Michael A. Grodin, George J. Annas, and Stephen P. Marks (eds.), Perspectives on Health and Human Rights. Oxford, UK: Routledge, 2005. 672 pp. $36.95, paperback
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21042496
retrieved
12 December 2020
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Identifiers
DOI
10.4103/0975-1483.66810
2 references
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pmc&retmode=json&id=2964774
retrieved
20 March 2017
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
668979
OpenCitations bibliographic resource ID
668979
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
668979
PMC publication ID
2964774
2 references
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pmc&retmode=json&id=2964774
retrieved
20 March 2017
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
668979
PubMed publication ID
21042496
2 references
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pmc&retmode=json&id=2964774
retrieved
20 March 2017
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
668979
ResearchGate publication ID
47645732
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